Efficacy of Traditional Chinese Medicine Combined with Artificial Insemination in Patients Undergoing Laparoscopic Surgery for Endometriosis

Objective To investigate the clinical efficacy of traditional Chinese medicine combined with artificial insemination in patients undergoing laparoscopic surgery for endometriosis.Methods Fifty patients who underwent laparoscopic surgery for endometriosis were randomly divided into two groups,with 25 patients in each group.Patients in control group were injected with 3.6 mg sustained release goserelin implants into anterior abdominal wall on postoperative day 28 for 3 times.Patients in treatment group were postoperatively given comprehensive therapy with traditional Chinese medicine(oral application,enema and external application) for 3 months.Artificial insemination was performed after treatment for 3 months in both groups.The relief of dysmenorrheal,changes in CA125 and EMAb levels,associated symptoms(anal pain,algopareunia,bradymenorrhea and excessive menstrual volume),ovulation rate,live birth rate,and abortion rate were compared between the two groups.Results There were no significant differences in the degree of dysmenorrheal,changes in CA125 and EMAb levels and associated symptoms between the two groups before treatment.After treatment,the dysmenorrhea and associated symptoms were obviously improved and serum CA125 levels and positive EMAb rates were remarkably decreased(all P0.05),but no significant differences were found between the two groups(all P0.05).In addition,there no were obvious differences in cumulative pregnancy rate,abortion rate and live birth rate between the two groups after 3 cycles of artificial insemination(all P0.05).Conclusion Traditional Chinese medicine combined with artificial insemination has an ideal analgesic effect in patients undergoing laparoscopic surgery for endometriosis and can inhibit ectopic endometrial activity and alleviate dysmenorrheal without adverse reactions.