The Heart Excitation Simulation Utility (HE-SU)
preprint
OA: closed
Abstract
Accurate modeling of cardiac excitation propagation requires detailed representation of both the myocardial structure and the ventricular conduction system. Traditional imaging methods like MRI and CT provide anatomical data but fail to capture the anisotropic properties essential for realistic simulations. This work presents an integrated modeling and simulation environment, HE-SU (Heart Excitation Simulation Utility), which employs pre-processed Diffusion Tensor Imaging (DTI) data to reconstruct myocardial fiber architecture and conduction pathways. The simulation is based on the Monodomain reaction-diffusion equation using the Aliev-Panfilov adaptation of the FitzHugh-Nagumo model. The software enables the adjustment of conductivity parameters and visualizes the propagation of excitation in 3D, supporting exportable reports for further analysis. This tool is valuable for researchers studying cardiac electrophysiology and the impact of anisotropic tissue properties on body surface potential mapping (BSPM).
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- europepmc
- last seen: 2026-05-20T01:45:00.602351+00:00