The Diagnostic Value of Serum TSGF and CA_(125) on Ovarian Tumors

Objective:To investigate the diagnostic value of TSGF(Tumor Supplied Group of Factors) and CA 125 on malignant ovarian neoplasm.Methods:Determine the levels of serum TSGF and CA 125 in 30 women cases of ovarian cancers,37 cases of benign ovarian tumor and 16 cases of endometrioses. Compare the diagnostic sensitivity, specificity and coincident ratio of two parameters. Results:The levels of TSGF and CA 125 of malignant group[(79.62±13.58) U/ml,(251.23±272.48) U/ml]are significantly higher than these of the endometriosis group[(58.47±14.51) U/ml,(69.76±109.73) U/ml, P 0.01)]and the benign group[(64.07±7.02) U/ml,(25.29±31.63) U/ml, P 0.01)];The level of CA 125 of malignant group is significantly higher than that of the endometriosis group( P 0.01),but the level of TSGF is not significant in the 2 groups. The positive rates of TSGF and CA 125 in malignant group(63.33%,76.67%)are significantly higher than those in the benign group (18.92%,7.14%, P 0.01)and in the endometriosis group(25.00%,31.25%, P 0.01).The sensitivities of TSGF and CA 125 to malignant ovarian tumor are only 63.33 % and 76.67%,but it will be up to 90.00% with 2 parameters at the same time. Conclusions:The determination of TSGF can be an auxiliary aid in diagnosing ovarian cancers, and can also make up the defect of CA 125 using to distinguish pelvic endometriosis and ovarian cancers; The determination of TSGF together with CA 125 can obviously improve the sensitivity to ovarian cancers.