Expression of livin and PCNA in adenomyosis

Objective To study the expression of livin,an apoptosis inhibitor gene,and expression of PCNA in adenomyosis.Methods Expression of PCNA protein and livin protein were detected by immunohistochemistry staining in humans ectopic and eutopic endometrial cells(from 30 women with adenomyosis) and eutopic endometrial cells(from 25 women without adenomyosis).Results PCNA expression in eutopic endometrium of adenomyosis was stronger than that in control group,and was lower than that in ectopic endometrium of adenomyosis(P0.05).There was no livin expression in eutopic endometrium and control group of adenomyosis,Livin expression in ectopic endometrium of adenomyosis was strong(P0.05).[WTHZ]Conclusion The apoptosis is inhibited while proliferation is improved,which is related to adenomyosis.