Epidemiologische Faktoren bei verschiedenen klinischen Formen der Endometriose – eine Fall-Fall-Untersuchung

The study aimed to divide a population of endometriosis patients into clinically meaningful subgroups based on the presence and localization of different disease forms and to compare patients’ characteristics across these groups. Using a retrospective case-case analysis of 1076 German and Austrian women with an operative first diagnosis captured in the IEEP web-based system, the authors created 15 subgroups using four criteria (peritoneal endometriosis, endometrioma, deep infiltrating endometriosis, and adenomyosis), then consolidated them into five broader groups. They found significant differences in mean age at first diagnosis (p<0.001), with women with isolated peritoneal endometriosis diagnosed about three years younger than those with adenomyosis (32.5 vs 35.9 years), and also significant differences in pregnancy rates and number of live births (both p<0.001). This paper is centrally about endometriosis — it uses epidemiologic/clinical subgrouping across peritoneal disease, endometrioma, deep infiltrating endometriosis, and includes adenomyosis as one classification criterion.

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