Safety and Efficacy of Dinogest in Long Term Treatment of Endometriosis

Shabina Khan; Sweety Raj; Shreshu Yadav

doi:10.21276/ijcmr.2019.6.9.35

Safety and Efficacy of Dinogest in Long Term Treatment of Endometriosis

Shabina Khan, Sweety Raj, Shreshu Yadav

In: International Journal of Contemporary Medical Research [IJCMR] · 2019 · vol. 6(9) · doi:10.21276/ijcmr.2019.6.9.35 · W3016277756

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Abstract

Endometriosis is a chronic disease characterized by the prolifera tion of endometrial tissue outside the uterine cavity, and it occurs in 6% to 10% of women of reproductive age and in 50% of infertile women. Current research aimed to study the safety and efficacy of dinogest 2mg daily in patients of endometriosis for a period of 12 months. Material and methods: This study was a retrospective non placebo randomized trial done in the department of obstetrics and gynaecology, RMCH. Patient data was collected in a span of 1year i.e; February 2018 to January 2019 and dinogest was given for 12 months thereafter. Total 100 women post surgery (cystectomy) with endometriosis were taken who had been treated with 2mg of dinogest once a day for 12 months. We evaluated changes in endometriosis associated pain, endometrioma size, recurrence rate and adverse events.