Non-Invasive Imaging Modalities for Stem Cells Tracking in Osteoarthritis

The administration of stem cells in regenerative medicine has emerged as a potential treatment option for many diseases. The privation of an impressive cure for joint pathologies such as knee osteoarthritis (OA) has increased concern in stem cell (SC)-based therapies. Many questions remain about the survival and biology of SC after transplantation. Current progression in molecular biology and imaging has accredited winsome non-invasive SC monitoring in living subjects. Over time, these methods have been updated to assess the viability and biology of SC transplantation. The use of nanoparticles has become important in many aspects of SCs tracking. Given that different tracking strategies are being used for clinical trials, it is important to choose the best one. In this review, various imaging methods, which were assimilated to monitor the viability and biology of SC after injection in osteoarthritis, were discussed.