The Value of Co-examination of CA_(125) and Solubility Fas, Fas-L in Adenomyosis

Objective:To co-examine the serum level of CA125, sFas and sFasL in patients with adenomyosis, and to discuss the clinical value of sFas and sFasL in adenomyosis. Methods:By ECL and ELISA technique, we determined the serum level of CA125 , sFas and sFasL in 30 cases of adenomyosis, then compared with 20 cases of hysteromyoma. Results: (1) After operation, the level of CA125 , sFas and sFasL in adenomyosis were significantly decreased, but there was no significant difference in hysteromyoma. (2) Before opreration, the level of CA125 , sFas and sFasL in adenomyosis greatly increased. (3)5 days after operation, the level of CA125, and sFasL in adenomyosis still increased than those in hysteromyoma, but the level of sFas of both was similar. Conclusion: (1) There was relationship between serum sFas,sFasL and the occurrence and development of adenomyosis. (2) sFasL could be a new serum marker of the diagnosis of adenomyosis, and play more important role in the observation of curative effect and the relapse estimation of the adenomyosis.