Efficacy evaluation for adenomyosis after high intensity focused ultrasound treatment

Objective To evaluate the efficacy,adverse events and influence for life quality of high intensity focused ultrasound( HIFU) for the treatment of adenomyosis. Methods Eighty-four female patients with adenomyosis were treated with the HIFU. The efficacy of ablation was evaluated by enhanced magnetic resonance imaging( MRI). The adverse event after treatment were recorded. Health-relatedquality of life of the patients were evaluated at 1 month,3 and 6 months after treatment using the MOS 36-item short form health survey( SF-36) health survey questionnaire. Results The dysmenorrhea symptom was improved in 80 patients and the total effective rate was 95. 2%. The dysmenorrhea scores were decreased significantly 1 month,3 and 6 months after operation compared with that before operation( P 0. 01). The ablation ratio of adenomyosis lesion detected by the enhanced MRI was( 73. 2 ± 17. 5) % after treatment. All side effects after treatment were under the B-level of the standard classification of Society of Interventional Radiology. Regarding SF-36 subscale scores,at 1 month,3 and 6 months there was improvement in physical functioning,social functioning,role physical,bodily pain,vitality,and role emotional subscales( P 0. 01). Conclusion HIFU treatment on adenomyosis can ablation the focus,release the clinical symptoms and improve the life quality quickly with few adverse events as a new expectant treatment.