A Case Report of Skin Necrosis Syndrome in a Child Caused by Extravasation of Concentrated Sodium Chloride

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Abstract

Hypertonic saline is a commonly employed and efficacious approach for mitigating acute elevations in intracranial pressure, which has gained broad acceptance. Although numerous research studies have demonstrated the rationale behind peripheral administration of concentrated sodium chloride with minimal risk of harm, infusion-related adverse effects such as drug leakage, phlebitis, and tissue

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00