Zyklusabhängiges T2 Mapping des Uterus junger Frauen bei klinischem Verdacht auf Adenomyose
T2 mapping of the uterus in young women did not reveal significant differences between those with suspected adenomyosis and controls, nor between menstrual and ovulation phases in the myometrium or junctional zone.
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The study investigated whether uterine tissue characterization using cycle-dependent T2 mapping MRI differs between symptomatic young women with a clinical suspicion of adenomyosis and asymptomatic volunteers, comparing scans at menstruation and the calculated ovulation time point. In a multicenter case-control design of 239 participants aged 12–30, the uterus was segmented into endometrium, myometrium (anterior/posterior), and junctional zone (anterior/posterior) for T2 mapping analysis. No significant differences in T2 values were found between the suspected-adenomyosis group and controls across endometrium, myometrium, and junctional zone, although significant endometrium changes occurred between menstruation and ovulation for both groups. This paper is centrally about endometriosis and/or adenomyosis—specifically adenomyosis—evaluating whether T2 mapping can distinguish suspected cases from asymptomatic controls while accounting for menstrual cycle timing.
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