Association between PM2.5 and its components and antral follicle count: A multicity study in Chinese adults
article
OA: closed
CC0
AI-generated summary
Exposure to PM<sub>2.5</sub> mass and its components (sulfate, nitrate, ammonium, organic matter, and black carbon) was associated with lower antral follicle count in Chinese women of reproductive age.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
Antral follicle count (AFC) is a key biomarker of ovarian reserve, however, its association with fine particulate matter (PM2.5) and its chemical components remains inadequately understood. In this study, we estimated the effects of PM2.5 mass and its components including sulfate (SO42-), nitrate (NO3-), ammonium (NH4+), organic matter (OM), and black carbon (BC) on AFC among women of reproductive age. We included 4053 women seeking infertility treatment in Sichuan and Hubei provinces, China. A multivariable negative binomial mixed-effect model with city as a random effect was employed to estimate the associations between PM2.5 and its components and AFC. Weighted quantile sum regression analysis was performed to evaluate the joint effect of PM2.5 components on AFC. Our findings showed that exposure to PM2.5 mass, SO42-,NO3-,NH4+, OM, and BC was associated with lower AFC. These results suggest that exposure to ambient PM2.5 and its chemical components may impair ovarian reserve. Targeted reduction of specific air pollutants represents a potential strategy to protect female reproductive health.
My notes (saved in your browser only)
Citation neighborhood (no data yet)
We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2025) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.
References (40)
- doi:10.1186/s12940-017-0242-4 via openalex
- doi:10.1080/08958370701402382 via openalex
- doi:10.1016/j.envint.2018.06.027 via openalex
- doi:10.1016/j.fertnstert.2009.04.040 via openalex
- doi:10.1093/aje/kws018 via openalex
- doi:10.4103/0366-6999.207472 via openalex
- doi:10.1126/sciadv.abm9359 via openalex
- doi:10.1021/acs.est.2c06510 via openalex
- doi:10.1016/j.ecoenv.2024.116915 via openalex
- doi:10.3389/fimmu.2016.00003 via openalex
- doi:10.1021/acs.chemrev.5b00067 via openalex
- doi:10.1016/j.envres.2009.03.006 via openalex
- doi:10.1016/j.envint.2024.108863 via openalex
- doi:10.1016/j.envint.2015.10.016 via openalex
- doi:10.1038/s41598-024-53558-3 via openalex
- doi:10.1021/acs.est.9b00449 via openalex
- doi:10.1002/oby.20748 via openalex
- doi:10.1002/smll.202000845 via openalex
- doi:10.1016/j.envint.2023.108382 via openalex
- doi:10.1016/j.jhazmat.2023.132579 via openalex
- doi:10.1093/humupd/dmt057 via openalex
- doi:10.1016/j.fertnstert.2020.09.134 via openalex
- doi:10.1093/humrep/der092 via openalex
- doi:10.1210/er.2009-0006 via openalex
- doi:10.1016/j.fertnstert.2021.05.091 via openalex
- doi:10.1016/j.envpol.2021.116868 via openalex
- doi:10.2174/1381612820666140205145319 via openalex
- doi:10.1021/acs.est.7b00312 via openalex
- doi:10.2471/b09461 via openalex
- doi:10.1016/j.fertnstert.2013.01.103 via openalex
- doi:10.1016/j.atmosres.2015.02.003 via openalex
- doi:10.3389/fimmu.2017.00763 via openalex
- doi:10.1016/j.scitotenv.2023.166744 via openalex
- doi:10.1021/acs.est.1c01863 via openalex
- doi:10.1016/j.envres.2014.10.010 via openalex
- doi:10.1093/eurheartj/ehz151 via openalex
- doi:10.1038/nature13774 via openalex
- doi:10.1097/ede.0000000000001029 via openalex
- doi:10.32614/rj-2017-066 via openalex
- doi:10.1016/j.envres.2021.111162 via openalex
Source provenance
- openalex
- last seen: 2026-05-11T06:52:22.631516+00:00
- unpaywall
- last seen: 2026-08-26T06:23:03.089193+00:00
License: CC0
· commercial use OK