Observational study of HSG with laparoscopic correlation in infertility patients

In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2018 · vol. 7(5) , pp. 1903 · doi:10.18203/2320-1770.ijrcog20181926 · W2800314317
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AI-generated summary by gemini-2.5-flash-lite, 2026-06-08

This study evaluated 61 infertility patients with HSG and correlated findings with laparoscopy in 25, finding HSG to have 90% sensitivity and 60% specificity for tubal block, suggesting HSG as an initial test with laparoscopy for confirmation and etiological investigation.

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This observational retrospective correlation study evaluated 61 infertility/subfertility patients by hysterosalpingography (HSG), with a subset of 25 undergoing diagnostic laparoscopy for comparison. HSG was reported as normal in 42 (68.8%) and abnormal in 19 (31.14%), with abnormalities including Müllerian abnormalities and unilateral/bilateral tubal occlusion; compared with laparoscopy, HSG had sensitivity of 90% and specificity of 60%, with positive and negative predictive values of 60% and 90%, respectively. The authors note a key limitation that only 25/61 patients had laparoscopy confirmation, and laparoscopy found causes among blocked tubes including peri-adnexal adhesions, endometriosis in 1 case, suspected intra-tubal block in 2 cases, and pelvic inflammatory disease in 3 cases. Relevance to endometriosis: endometriosis was detected/suspected as a cause of tubal block on laparoscopy (endometriosis detected in 1 blocked tube and suspected intra-tubal block in 2), though the paper’s main focus is the diagnostic accuracy of HSG versus laparoscopy in infertility.

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Abstract

Background: Uterine abnormalities contribute to 10% of infertility cases and 50% of women with recurrent early pregnancy loss whereas fallopian tube abnormalities contribute to 20% of such cases.Methods: Total 61 patients of infertility and subfertility undergoing evaluation and treatment at our centre were selected for HSG. Total 25 patients from this group have undergone diagnostic laparoscopy, their findings were correlated with HSG findings retrospectively.Results: All the patients in the study group were either primary or secondary infertility patients. Of the 61 patients of infertility, 49 were in primary infertility group and 12 were in secondary infertility group. The age of patients was between 23 and 35 years. The average duration of primary infertility was 5 years and secondary infertility was 3.5years. Total 61 patients underwent HSG, 42(68.8%) patients had normal findings and 19(31.14%) patients had abnormal findings. In abnormal findings 4(6.55%) were Mullerian abnormalities and 15(24.59%) were either unilateral or bilateral tubal block. Total 25 patients underwent diagnostic laparoscopy out of 61 patients. The sensitivity of HSG was 90% and specificity was 60 % with positive predictive value of 60% and negative predictive value of 90% as compared to diagnostic laparoscopy. Tubal block was defined as any form of tubal occlusion detected at HSG and finally confirmed on laparoscopy. In our laparoscopy findings, peri-adnexal adhesions were found in 5 (20%) of the blocked tubes on laparoscopy. Endometriosis was detected in 1 (4%) of the blocked tubes and suspected intra-tubal block in 2 (8%).Pelvic inflammatory disease was found to contribute in 3 (12%).Conclusions: HSG demonstrates high sensitivity in our study. So, it should be used as the initial investigation for identifying uterine abnormality and tubal patency. As the specificity is less, we suggest that laparoscopy is necessary to recognize those cases of tubal block, which were unrecognized or wrongly recognized on HSG. In addition, the patients who were found to have tubal block on HSG, laparoscopy helps in finding the cause of infertility like existence of peritubal adhesions and endometriosis that can guide appropriate therapy.
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Background

Uterine abnormalities contribute to 10% of infertility cases and 50% of women with recurrent early pregnancy loss whereas fallopian tube abnormalities contribute to 20% of such cases.

Methods

Total 61 patients of infertility and subfertility undergoing evaluation and treatment at our centre were selected for HSG. Total 25 patients from this group have undergone diagnostic laparoscopy, their findings were correlated with HSG findings retrospectively.

Results

All the patients in the study group were either primary or secondary infertility patients. Of the 61 patients of infertility, 49 were in primary infertility group and 12 were in secondary infertility group. The age of patients was between 23 and 35 years. The average duration of primary infertility was 5 years and secondary infertility was 3.5years. Total 61 patients underwent HSG, 42(68.8%) patients had normal findings and 19(31.14%) patients had abnormal findings. In abnormal findings 4(6.55%) were Mullerian abnormalities and 15(24.59%) were either unilateral or bilateral tubal block. Total 25 patients underwent diagnostic laparoscopy out of 61 patients. The sensitivity of HSG was 90% and specificity was 60 % with positive predictive value of 60% and negative predictive value of 90% as compared to diagnostic laparoscopy. Tubal block was defined as any form of tubal occlusion detected at HSG and finally confirmed on laparoscopy. In our laparoscopy findings, peri-adnexal adhesions were found in 5 (20%) of the blocked tubes on laparoscopy. Endometriosis was detected in 1 (4%) of the blocked tubes and suspected intra-tubal block in 2 (8%).Pelvic inflammatory disease was found to contribute in 3 (12%).

Conclusions

HSG demonstrates high sensitivity in our study. So, it should be used as the initial investigation for identifying uterine abnormality and tubal patency. As the specificity is less, we suggest that laparoscopy is necessary to recognize those cases of tubal block, which were unrecognized or wrongly recognized on HSG. In addition, the patients who were found to have tubal block on HSG, laparoscopy helps in finding the cause of infertility like existence of peritubal adhesions and endometriosis that can guide appropriate therapy. Metrics

References

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