Pollutions and Incidence of Liver and Breast Cancer in Damietta Governorate, Egypt: A Multiregional Analysis

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Abstract Cancer stands as a pervasive global health concern, ranking among the leading causes of morbidity and mortality worldwide. This paper addresses this challenge by presenting a focused analysis of liver and breast cancer incidence rates in Damietta Governorate, Egypt, utilizing statistical data from 2021.The study meticulously divided Damietta Governorate into distinct regions for comprehensive analysis. Medical records, comprising 128 cases for liver cancer and 100 cases for breast cancer, were diligently collected from Damietta Cancer Center's Oncology Institute and death records throughout 2021. Incidence rates for both cancers were meticulously analyzed, considering factors such as sex, age, occupation, location, stage, grade, and diagnosis. The results highlighted a significant increase in liver cancer incidence rates by 2021, signaling a growing burden in Damietta Governorate. Similarly, projections indicated an upward trend in breast cancer incidence rates, with distinct variations observed in types like duct carcinoma and infiltrating duct carcinoma across specific regions. Noteworthy differences were also observed in age groups, marital status, and occupation. This study contributes valuable insights into the escalating incidence of liver and breast cancer in Damietta Governorate, emphasizing the urgency of continued monitoring and intervention efforts. The specific nuances in breast cancer types and demographic variations underscore the necessity for targeted strategies to alleviate the escalating burden of these diseases in the region. Ongoing surveillance and effective interventions are paramount to combat the rising incidence of liver and breast cancer in Damietta Governorate. Our results suggest a potential correlation between environmental pollution and cancer incidence rates in Damietta Governorate. Given the region's industrial activities and environmental challenges, the link between pollution and cancer warrants further investigation. Understanding and addressing the impact of pollution on cancer rates is crucial for developing effective prevention and intervention strategies.
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Pollutions and Incidence of Liver and Breast Cancer in Damietta Governorate, Egypt: A Multiregional Analysis | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Pollutions and Incidence of Liver and Breast Cancer in Damietta Governorate, Egypt: A Multiregional Analysis Elhossein A Moawed, Omnia H Gohar, Wael S El–tohamy, Heba O El Sharawy, and 3 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4655729/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Cancer stands as a pervasive global health concern, ranking among the leading causes of morbidity and mortality worldwide. This paper addresses this challenge by presenting a focused analysis of liver and breast cancer incidence rates in Damietta Governorate, Egypt, utilizing statistical data from 2021.The study meticulously divided Damietta Governorate into distinct regions for comprehensive analysis. Medical records, comprising 128 cases for liver cancer and 100 cases for breast cancer, were diligently collected from Damietta Cancer Center's Oncology Institute and death records throughout 2021. Incidence rates for both cancers were meticulously analyzed, considering factors such as sex, age, occupation, location, stage, grade, and diagnosis. The results highlighted a significant increase in liver cancer incidence rates by 2021, signaling a growing burden in Damietta Governorate. Similarly, projections indicated an upward trend in breast cancer incidence rates, with distinct variations observed in types like duct carcinoma and infiltrating duct carcinoma across specific regions. Noteworthy differences were also observed in age groups, marital status, and occupation. This study contributes valuable insights into the escalating incidence of liver and breast cancer in Damietta Governorate, emphasizing the urgency of continued monitoring and intervention efforts. The specific nuances in breast cancer types and demographic variations underscore the necessity for targeted strategies to alleviate the escalating burden of these diseases in the region. Ongoing surveillance and effective interventions are paramount to combat the rising incidence of liver and breast cancer in Damietta Governorate. Our results suggest a potential correlation between environmental pollution and cancer incidence rates in Damietta Governorate. Given the region's industrial activities and environmental challenges, the link between pollution and cancer warrants further investigation. Understanding and addressing the impact of pollution on cancer rates is crucial for developing effective prevention and intervention strategies. Biological sciences/Biochemistry Earth and environmental sciences/Environmental social sciences Damietta Liver cancer Cases Rate Breast Cancer Duct carcinoma Pollution Full Text Additional Declarations No competing interests reported. Supplementary Files Supplementarydata.docx Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4655729","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":334686379,"identity":"694159e6-9451-4ec7-bd87-f969ef56d9d5","order_by":0,"name":"Elhossein A Moawed","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAyUlEQVRIiWNgGAWjYBADxn4GBjYStcxsIFnLhgPEauFnP5344GebjezmG8nPHnyoYJDnFzuAX4tkT+5mw962NONtN9LMDWecYTCcOTsBvxaDA7nbJHi3HU7cdiPBTJq3jSHB4DYBLfbn326T/Lvtf+LmGenfiNNiIJG7TZp324HEDRI5RNoicePtZmPZf8nGM868KZOccUaCsF/4+3M3Pnxzxk62vz19m8SHCht5fmkCWhBAAKxSgljlYPsOkKJ6FIyCUTAKRhIAAPn7RpzviN21AAAAAElFTkSuQmCC","orcid":"","institution":"Damietta University","correspondingAuthor":true,"prefix":"","firstName":"Elhossein","middleName":"A","lastName":"Moawed","suffix":""},{"id":334686380,"identity":"69f9dfa8-4b17-4c3c-96d7-2aa88683c69f","order_by":1,"name":"Omnia H Gohar","email":"","orcid":"","institution":"Damietta Cancer Institute","correspondingAuthor":false,"prefix":"","firstName":"Omnia","middleName":"H","lastName":"Gohar","suffix":""},{"id":334686381,"identity":"9a149d5e-6861-4230-9382-1e60d5544b30","order_by":2,"name":"Wael S El–tohamy","email":"","orcid":"","institution":"Damietta University","correspondingAuthor":false,"prefix":"","firstName":"Wael","middleName":"S","lastName":"El–tohamy","suffix":""},{"id":334686382,"identity":"10533fd6-a7e5-4058-a65a-13b372752d7e","order_by":3,"name":"Heba O El Sharawy","email":"","orcid":"","institution":"Damietta University","correspondingAuthor":false,"prefix":"","firstName":"Heba","middleName":"O El","lastName":"Sharawy","suffix":""},{"id":334686383,"identity":"f0bd249e-b531-4fb8-a560-c0db1fd1844e","order_by":4,"name":"Mohamed M. 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