Hat die Ausprägung, Ausdehnung und Lokalisation der peritonealen Endometriose einen prädiktiven Wert für Schmerzsymptomatik und Sterilität?

B. Afflerbach, R. Callies, U. Rohr, Ludwig Kiesel, Pedro‐Antonio Regidor
In: Geburtshilfe und Frauenheilkunde · 2002 · vol. 62(8) , pp. 772–776 · doi:10.1055/s-2002-33719 · W281486230
Observational OA: closed CC0
Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by qwen3.7-flash, 2026-09-03 ⓘ

This study evaluated the predictive value of peritoneal endometriosis extent, localization, and revised-AFS stage for pain symptoms and sterility in patients undergoing medical or surgical therapy.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-23 · read from full text ⓘ

This study investigated whether the extent, localization, and revised-AFS scoring of peritoneal endometriosis predict chronic pelvic pain or sterility in 117 patients treated between 1994 and 1995. Researchers analyzed clinical data collected via questionnaires to determine correlations between disease stage, lesion location, and symptoms such as dysmenorrhea, dyspareunia, and infertility. The analysis revealed no statistically significant relationship between the severity of these symptoms or the likelihood of sterility and the anatomical characteristics of the endometriotic lesions. This paper is centrally about endometriosis — specifically evaluating the predictive value of disease staging and localization for pain and fertility outcomes.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Der Zusammenhang zwischen der Ausprägung der Endometriose, der Lokalisation im Bereich des kleinen Beckens und dem klinischen Erscheinungsbild ist immer noch unklar. Das Ziel der vorliegenden Arbeit ist es, die Ausdehnung sowie die typischen Symptome der Endometriose (Dysmenorrhöen, Dyspareunien und azyklische Beckenschmerzen) vor und nach der medikamentösen und chirurgischen Therapie darzustellen sowie eine statistisch signifikante Beziehung zwischen der Intensität der Beschwerden, der Sterilität und dem Stadium der Endometriose nach dem revised-AFS-Score zu finden. Darüber hinaus wurde in diesem Zusammenhang die Lokalisation der Endometriosis genitalis externa untersucht, um den prädiktiven Wert des revised-AFS-Scores und der Lokalisation der Endometriose in Bezug auf die Schmerzen und die Sterilität der Patientin zu beurteilen.
Full text 6,697 characters · extracted from oa-doi-fallback · 5 sections · click to expand

Material

und Methoden Insgesamt wurden 117 Patientinnen ausgewählt, die in den Jahren 1994 und 1995 im Zentrum für Frauenheilkunde der Universitätskliniken Essen aufgrund einer Endometriose behandelt wurden. Die klinischen Daten der Patientinnen wurden mit Hilfe eines Endometriosefragebogens aufgenommen. Anschließend erfolgten statistische Analysen in sechs Patientinnengruppen. Ergebnisse Die Ergebnisse zeigen, dass es zwischen der Ausprägung der Endometriose nach dem revised-AFS-Score, der Lokalisation der Endometrioseherde und dem klinischen Erscheinungsbild der Erkrankung mit Schmerzen und Sterilität keine statistisch signifikanten Zusammenhänge gibt. Schlussfolgerung Die Ausprägung der Endometriose nach dem revised-AFS-Score und die Lokalisation im Bereich des kleinen Beckens besitzen keinen prädiktiven Wert für die Schmerz- und Sterilitätsproblematik der Patientin.

Abstract

Objective The relationship between the revised-AFS-Score of endometriosis and its localization in the pelvis concerning the severity of pelvic pain and sterility is still unknown. The aim of this investigation was to represent the typical symptoms of endometriosis (dysmenorrhea, dyspareunia and pelvic pain), to show the improvement of endometriosis after medical and surgical treatment and to find a significant correlation between the severity of pelvic pain, sterility and the extent of the disease. Furthermore the relationship between the localization of endometriotic lesions in the pelvis and the severity of symptoms and sterility was investigated. The intention was to assess the predictive value of the revised-AFS-Score and the localization of endometriosis for pelvic pain and sterility.

Material and methods

A total of 117 patients who were treated for endometriosis in 1994 and 1995 were included into the investigation. A questionnaire was completed and the patients were divided into six groups. Within the groups the statistical analysis was realized.

Results

The findings of the analysis show that there is no significant correlation between the extent of endometriosis and its localization in the pelvis concerning the severity of pelvic pain and sterility.

Conclusion

The revised-AFS-Score and the localization of endometriotic lesions in the pelvis have no predictive value for pelvic pain and sterility. Schlüsselwörter Endometriose - Revised-AFS-Score - Lokalisation - Schmerzen - Sterilität Key words Endometriosis - Revised-AFS-Score - Localization - Pain - Sterility Literatur - 1 Ranney B. Etiology, prevention, and inhibition of endometriosis. Clin Obstet Gynecol. 1980; 23 875-882 - 2 Römer T, Putz A. Der Teufelskreis der Endometriose. Zentralbl Gynäkol. 1999; 121 305-311 - 3 Sampson J A. Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol. 1927; 14 422-469 - 4 Kistner R W. Endometriosis and infertility. Clin Obstet Gynecol. 1979; 22 101-119 - 5 The American Fertility Society . Revised American Fertility Society classification of endometriosis:1985. Fertil Steril. 1985; 43 351-352 - 6 Regidor P A, Regidor M, Kato K, Bier U W, Bühler K, Schindler A E. Long-term follow-up on the treatment of endometriosis with the GnRH-agonist buserelinacetate. Long-term follow-up data (up to 98 months) of 42 patients with endometriosis who were treated with GnRH-agonist buserelinacetate (Suprecur®), were evaluated in respect of recurrence of pain symptoms and pregnancy outcome. Eur J Obstet Gynecol Reprod Biol. 1997; 73 153-160 - 7 Regidor P A, Heck M, Regidor M, Kimmig R, Rohr D U, Schindler A E. Langzeitergebnisse in der Behandlung der Endometriose mit dem GnRH-Agonisten Nafarelinacetat (Synarela®). Geburtsh Frauenheilk. 2002; 62 578-584 - 8 Kienle E, Hillger H, Hübner R, Jost V. Prospektive, randomisierte Studie zur Pharmakodynamik, Pharmakokinetik und Bioäquivalenz des GnRH-Analogons Leuprorelinacetat als 1- und 3-Monats-Depot bei Uterus myomatosus. Geburtsh Frauenheilk. 2001; 61 788-793 - 9 Schindler A E. Kombiniertes chirurgisch-hormonelles Management der Endometriose. Langzeit-Follow-up. Zentralbl Gynäkol. 1999; 121 325-329 - 10 Fedele L, Parazzini F, Bianchi S, Arcaini L, Candiani G B. Stage and localization of pelvic endometriosis and pain. Fertil Steril. 1990; 53 155-158 - 11 Vercellini P, Trespidi L, De Giorgi O, Cortesi I, Parazzini F, Crosignani P G. Endometriosis and pelvic pain: relation to disease stage and localization. Fertil Steril. 1996; 65 299-304 - 12 Perper M M, Nezhat F, Goldstein H, Nezhat C H, Nezhat C. Dysmenorrhea is related to the number of implants in endometriosis patients. Fertil Steril. 1995; 63 500-503 - 13 Guzick D S, Silliman N P, Adamson G D, Buttram V C, Canis M, Malinak L R, Schenken R S. Prediction of pregnancy in infertile women based on the American Society for Reproductive Medicine's revised classification of endometriosis. Fertil Steril. 1997; 67 822-829 - 14 Hadfield R, Mardon H, Barlow D, Kennedy S. Delay in the diagnosis of endometriosis: a survey of women from the USA and the UK. Hum Reprod. 1996; 11 878-880 PD Dr. med. Pedro-Antonio Regidor Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe der Westfälischen Wilhelms-Universität Münster Albert-Schweitzer-Straße 33 48149 Münster Email: [email protected] Email: [email protected]

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosisdie_deep_infiltrating

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
unpaywall
last seen: 2026-10-11T06:28:45.473802+00:00
License: CC0 · commercial use OK