Analysis of Single Knee Model Based on Finite Element Method: Effects of Knee Bending Angle and Load Distribution on Stress and Strain of Tibial Plateau

Analysis of Single Knee Model Based on Finite Element Method: Effects of Knee Bending Angle and Load Distribution on Stress and Strain of Tibial Plateau | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Analysis of Single Knee Model Based on Finite Element Method: Effects of Knee Bending Angle and Load Distribution on Stress and Strain of Tibial Plateau Tao Xiong, LiLi Zhao This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7671278/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background Knee osteoarthritis (OA) pain is often activity-dependent, indicating that joint biomechanics are highly influenced by knee posture and loading conditions. Understanding how tibial plateau stress and strain change dynamically with flexion angle and load distribution is crucial for elucidating the pathogenesis of OA and optimizing non-surgical and surgical interventions. Objective This study aimed to investigate the stress and strain distribution in the tibial plateau under different knee flexion angles and loading conditions using finite element analysis, to provide mechanical insights into the symptomatic progression of OA. Methods A parametric finite element model of a healthy adult knee was developed. Simulations were conducted across various flexion angles (0°, 30°, 45°, 60°) under two load distribution ratios: a normal ratio (60% medial/40% lateral) and an OA-simulated ratio (85% medial/15% lateral). The effects of increasing load magnitude at each angle were also assessed. Results The study revealed a nonlinear relationship between flexion angle and mechanical response. Under normal loading, peak stress increased with flexion, while maximum strain was minimized at 45°. However, under OA-like loading (85/15), the angle for minimum strain shifted to 60°, and a surprising reduction in peak stress was observed at high flexion angles (45° and 60°) despite increased load. This indicates a fundamental shift in load-bearing mechanisms in the diseased knee. Conclusion These findings provide a biomechanical explanation for why OA patients may experience less pain in deep flexion activities (e.g., squatting) despite higher loads, as the stress on the tibial plateau may actually decrease. This study highlights the importance of evaluating knee mechanics throughout the range of motion, rather than solely in a static posture. The results offer valuable insights for planning targeted rehabilitation exercises and for improving the biomechanical rationale behind procedures like high tibial osteotomy. Tibial Plateau Osteoarthritis Finite Element Analysis Biomechanics Knee Flexion Angle Load Distribution Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-7671278","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":527758389,"identity":"c61e429b-84ae-43c4-8257-5618e43f0995","order_by":0,"name":"Tao Xiong","email":"","orcid":"","institution":"Hebei North University","correspondingAuthor":false,"prefix":"","firstName":"Tao","middleName":"","lastName":"Xiong","suffix":""},{"id":527758390,"identity":"d562f3c3-354e-4373-b321-05ee7ba226e2","order_by":1,"name":"LiLi 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Plateau","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Tibial Plateau, Osteoarthritis, Finite Element Analysis, Biomechanics, Knee Flexion Angle, Load Distribution","lastPublishedDoi":"10.21203/rs.3.rs-7671278/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-7671278/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003ch2\u003eBackground\u003c/h2\u003e\u003cp\u003eKnee osteoarthritis (OA) pain is often activity-dependent, indicating that joint biomechanics are highly influenced by knee posture and loading conditions. Understanding how tibial plateau stress and strain change dynamically with flexion angle and load distribution is crucial for elucidating the pathogenesis of OA and optimizing non-surgical and surgical interventions.\u003c/p\u003e\u003ch2\u003eObjective\u003c/h2\u003e\u003cp\u003eThis study aimed to investigate the stress and strain distribution in the tibial plateau under different knee flexion angles and loading conditions using finite element analysis, to provide mechanical insights into the symptomatic progression of OA.\u003c/p\u003e\u003ch2\u003eMethods\u003c/h2\u003e\u003cp\u003eA parametric finite element model of a healthy adult knee was developed. Simulations were conducted across various flexion angles (0\u0026deg;, 30\u0026deg;, 45\u0026deg;, 60\u0026deg;) under two load distribution ratios: a normal ratio (60% medial/40% lateral) and an OA-simulated ratio (85% medial/15% lateral). The effects of increasing load magnitude at each angle were also assessed.\u003c/p\u003e\u003ch2\u003eResults\u003c/h2\u003e\u003cp\u003eThe study revealed a nonlinear relationship between flexion angle and mechanical response. Under normal loading, peak stress increased with flexion, while maximum strain was minimized at 45\u0026deg;. However, under OA-like loading (85/15), the angle for minimum strain shifted to 60\u0026deg;, and a surprising reduction in peak stress was observed at high flexion angles (45\u0026deg; and 60\u0026deg;) despite increased load. This indicates a fundamental shift in load-bearing mechanisms in the diseased knee.\u003c/p\u003e\u003ch2\u003eConclusion\u003c/h2\u003e\u003cp\u003eThese findings provide a biomechanical explanation for why OA patients may experience less pain in deep flexion activities (e.g., squatting) despite higher loads, as the stress on the tibial plateau may actually decrease. This study highlights the importance of evaluating knee mechanics throughout the range of motion, rather than solely in a static posture. The results offer valuable insights for planning targeted rehabilitation exercises and for improving the biomechanical rationale behind procedures like high tibial osteotomy.\u003c/p\u003e","manuscriptTitle":"Analysis of Single Knee Model Based on Finite Element Method: Effects of Knee Bending Angle and Load Distribution on Stress and Strain of Tibial Plateau","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-10-13 16:29:30","doi":"10.21203/rs.3.rs-7671278/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"d71798e2-cd99-4d7e-bc92-b85e3ff60d8c","owner":[],"postedDate":"October 13th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2025-10-28T18:15:29+00:00","versionOfRecord":[],"versionCreatedAt":"2025-10-13 16:29:30","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-7671278","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-7671278","identity":"rs-7671278","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}