Дифференциальная диагностика и лечение депрессивных расстройств у женщин в период климактерия

Neuroendocrine reorganization in a menopausal woman is frequently accompanied by the development of the climacteric syndrome with concomitant mental disorders. Furthermore, various mental disorders, depressions in particular, can manifest themselves in this period. The paper presents the results of examining 150 women aged 41 to 65 years who had depressive disorders in menopause. Based on the findings, the author considers depressions of varying genesis occurring in women in the preand postmenopausal periods, their association with menopausal symptoms and social factors. She outlines the differential diagnosis of depressions and the basic principles of their therapy, including indications for and contraindications to hormone replacement therapy and the use of psychotropic drugs.