Rotenone nanoparticles based on mesoporous silica to improve the stability, translocation and insecticidal activity of rotenone

Rotenone nanoparticles based on mesoporous silica to improve the stability, translocation and insecticidal activity of rotenone | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Rotenone nanoparticles based on mesoporous silica to improve the stability, translocation and insecticidal activity of rotenone Wangjin Xu, Dianjing Shen, xiaojun Chen, Ming Zhao, Tianle Fan, and 3 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3166413/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 19 Sep, 2023 Read the published version in Environmental Science and Pollution Research → Version 1 posted 6 You are reading this latest preprint version Abstract Nanotechnology has been widely applied for pesticide carriers and is considered an important approach to improve the utilization, stability, and prolonged release rates of pesticides. Mesoporous silica nanoparticles (MSNs) are a nanomaterial with adjustable particle and pore sizes, with a high specific surface area and good biocompatibility. Rotenone is a non-systemic botanical insecticide that is easily degraded in the environment. We used a modified soft-template method to prepare MSNs, to which rotenone was loaded using the solvent evaporation method. The prepared rotenone nanopesticide based on mesoporous silica showed considerable drug loading rates of 33.2%. Moreover, the prepared rotenone nanoparticles showed improved photostability and sustained release behavior, which improved the translocation of rotenone in tomato plants. Finally, the rotenone nanoparticles displayed superior insecticidal activity compared to traditional preparations. In summary, the rotenone nanopesticide improved the persistence and utilization rates of rotenone. These findings are of significance in reducing pesticide usage, mitigating environmental pollution, and ensuring food safety. Mesoporous silica nanopesticide botanical insecticide release properties translocation insecticidal activity Full Text Supplementary Files 20230718Supportinginformation.docx Cite Share Download PDF Status: Published Journal Publication published 19 Sep, 2023 Read the published version in Environmental Science and Pollution Research → Version 1 posted Editorial decision: Major Revision 10 Aug, 2023 Reviewers agreed at journal 31 Jul, 2023 Reviewers invited by journal 31 Jul, 2023 Editor invited by journal 31 Jul, 2023 Editor assigned by journal 24 Jul, 2023 First submitted to journal 19 Jul, 2023 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3166413","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":222990515,"identity":"fd430e8f-1218-4fd2-a1f3-1786d8e3d111","order_by":0,"name":"Wangjin Xu","email":"","orcid":"","institution":"Yangzhou University","correspondingAuthor":false,"prefix":"","firstName":"Wangjin","middleName":"","lastName":"Xu","suffix":""},{"id":222990516,"identity":"c084f324-d15f-444e-aa28-ce27f7853206","order_by":1,"name":"Dianjing Shen","email":"","orcid":"","institution":"Yangzhou 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