Endometrial Osseous Metaplasia: A Retrospective Analysis and Systematic Review

Endometrial osseous metaplasia is a rare condition defined as the presence of heterotopic bone in the endometrium. A retrospective, monocentric analysis was conducted, including patients with endometrial osseous metaplasia, and a systematic review of the literature was performed. The retrospective analysis included 10 cases. Most patients (n = 9) were of reproductive age and had a history of miscarriage. The main symptoms were infertility (n = 4) and menstrual cycle disorders (n = 4). The size and the uterine site of the metaplasia varied. It is crucial not to underestimate it, especially in infertile patients with anamnesis of recurrent miscarriages. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.

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