Comparison of unilateral and bilateral tubal transfer in gamete intrafallopian transfer (GIFT)

In: Journal of In Vitro Fertilization and Embryo Transfer · 1991 · vol. 8(5) , pp. 276–278 · doi:10.1007/bf01139784 · PMID:1757741 · W2057795346
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This retrospective review found similar clinical pregnancy rates between unilateral and bilateral tubal transfer in GIFT, suggesting unilateral transfer is preferred due to less gamete handling.

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This nonrandomized retrospective study compared unilateral versus bilateral tubal transfer in gamete intrafallopian transfer (GIFT), analyzing 399 tubal gamete transfers performed over 18 months (133 into a single tube and 266 into both tubes), with group assignment made by surgeon judgment based on anatomy, oocyte number, and clinical factors. The clinical pregnancy rate was approximately 24% in each modality, and the multiple pregnancy rate for unilateral transfer (31.3%) was not significantly different from that for bilateral transfer (25%). The authors report advantages of unilateral transfer in terms of less gamete and tissue handling. The paper’s limitations include its nonrandomized design and retrospective nature. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Gamete intrafallopian transfer (GIFT) is traditionally performed by delivering gametes into the ampullary region of either one or two fallopian tubes. The choice is made by the surgeon at the time of laparoscopy based upon the patient's anatomy, the number of oocytes available, and clinical judgment. In this nonrandomized, retrospective review, 399 tubal gamete transfers were performed over a period of 18 months, 133 to a single tube and 266 to both tubes. A clinical pregnancy rate of approximately 24% was observed in each modality. The multiple pregnancy rate of 31.3% for one tube was not significantly different from the 25% seen for two tubes. Unilateral tubal transfer offers the distinct advantages of less gamete and tissue handling. This, along with the apparent same outcome parameters, makes unilateral tubal transfer the preferred method of returning gametes at GIFT.
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Abstract

Gamete intrafallopian, transfer (GIFT) is traditionally performed by delivering gametes into the ampullary region of either one or two fallopian tubes. The choice is made by the surgeon at the time of laparoscopy based upon the patient's anatomy, the number of oocytes available, and clinical judgment. In this nonrandomized, retrospective review, 399 tubal gamete transfers were performed over a period of 18 months, 133 to a single tube and 266 to both tubes. A clinical pregnancy rate of approximately 24% was observed in each modality. The multiple pregnancy rate of 31.3% for one tube was not significantly different from the 25% seen for two tubes. Unilateral tubal transfer offers the distinct advantages of less gamete and tissue handling. This, along with the apparent same outcome parameters, makes unilateral tubal transfer the preferred method of returing gametes at GIFT. Similar content being viewed by others

References

Braeckmans P, Devroey P, Camus P, Kahn I, Staessen C, Smitz J, Van Vaesberghe L, Wisanto A, Van Steirteghem AC: Gamete intrafallopian transfer: Evaluation of 100 consecutive attempts. Hum Reprod 1987;2:201 Haines CJ, O'Shea RT: Unilateral gamete intrafallopian transfer: The preferred method? Fertil Steril 1989; 51:518 O'Shea RT, Haines CJ, Jones WR: Unilateral versus bilateral gamete intrafallopian transfer—A prospective randomised controlled trial. Presented at the 45th annual meeting of the American Fertility Society, San Francisco, CA, November 13–16, 1989, abstract P-220 Penzias AS, Thompson IE, Alper MM, Oskowitz SP, Berger MJ: Successful use of gamete intrafallopian transfer (GIFT) does not reverse the decline in fertility in women over 40 years of age. Obstet Gynecol 1991;77:37–39 Penzias AS, Alper MM, Oskowitz SP, Berger MJ, Thompson IE: Gamete intrafallopian transfer (GIFT): Assessment of the optimal number of oocytes to transfer. Fertil Steril 1991;55:311–313 Bates RG, Fielding PM, Lindsay KS, White NJ, Edmonds DK: Programmed gamete intrafallopian transfer (GIFT). Br J Obstet Gynecol 1988;95:1220 Yee B, Rosen GF, Chacon RR, Soubra S, Stone S: Gamete intrafallopian transfer: The effect of the number of eggs used and the depth of gamete placement on pregnancy initiation. Fertil Steril 1989;52:639–644 Author information Authors and Affiliations Rights and permissions About this article Cite this article Penzias, A.S., Alper, M.M., Oskowitz, S.P. et al. Comparison of unilateral and bilateral tubal transfer in gamete intrafallopian transfer (GIFT). J Assist Reprod Genet 8, 276–278 (1991). https://doi.org/10.1007/BF01139784 Received: Accepted: Issue date: DOI: https://doi.org/10.1007/BF01139784

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