Toxocara cati and other parasitic enteropathogens: more commonly found in owned cats with gastrointestinal signs than in clinically healthy ones

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Ursache, Adriana Györke, Viorica Mircean, Mirabela Oana Dumitrache, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-153658/v2 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 13 Feb, 2021 Read the published version in Pathogens → Version 2 posted You are reading this latest preprint version Show more versions Abstract Gastrointestinal parasites are involved in the health and wellbeing of cats and some of them, due to their zoonotic character represent a problem for the public health. This study aimed to assess the prevalence of parasitic infections in cats with digestive symptoms . Faecal samples collected from 137 cats were analysed by the flotation method using sodium chloride saturated solution. The overall prevalence of gastrointestinal (GI) parasites was 56.6%. GI parasites were significantly (p=0.005) more common in cats with digestive symptoms (69.8%) than in clinically healthy ones (23.0%). Toxocara cati (40.2%) was the most frequently identified GI parasite, followed by Cystoisospora spp. (10.2%), Ancylostoma tubaeforme (3.7%), Taenia spp. (2.2), Giardia duodenalis (2.2%), and Toxoplasma gondii -like oocysts (0.7%). T. cati (53.3%, p <0.0001) and Cystoisospora spp. (15.6%, p<0.001) were significantly more frequently diagnosed in cats with digestive symptoms. Lack of deworming in the last three months (OR: 15.9), outdoor access (OR: 13.8), the presence of digestive symptoms (OR: 5.4), and young age (OR: 4.2) were identified as risk factors for T. cati infection by logistic regression analysis. Regardless of the age, symptoms like vomiting, diarrhoea, and inappetence were positively associated with T. cati . Parasitology T. cati enteropathogens parasites gastrointestinal signs cats risk factors Figures Figure 1 Introduction In the last years, the number of cats increased considerably in the urban areas worldwide. It is considered that the proven benefits of companion animals to the mental, emotional, and physical health of humans [1] might play an important role in this dynamic. By the year 2019, in Europe, approximately 106.4 million cats were estimated to be raised as pets and Romania is one of the countries with a considerable interest for feline companionship, with 47% of the households owning at least one cat [2,3]. Gastrointestinal disorders are a common concern of the owner when bringing the cat to the veterinary clinics for a health check-up [4,5]. The identification of the underlaying cause can be a challenge for clinicians, but it is desirable for an efficient and complete therapeutic protocol and management. Among dietary and stress-related problems or intestinal primary disorders, various pathogens such as viruses, bacteria, and parasites can be responsible for the development of gastrointestinal (GI) signs in companion animals [6,7]. Parasitic enteropathogens, both protozoa and helminths, are numerous and one of the causes for gastrointestinal disturbances expressed by diarrhoea, vomiting and/or changes in appetite [8,9], therefore faecal testing must be taken into consideration for differential diagnosis whenever digestive clinical signs are present [10]. Moreover, it is necessary to protect human-animal interaction by limiting the exposure to various infectious agents that can represent a risk to both cats and humans such as Toxocara cati , hookworms, Giardia duodenalis , Toxoplasma gondii , Dipilidium caninum and Echinoccocus multilocularis [11,12]. Toxocara cati is a nematode frequently found in the intestine of domestic cats worldwide, with differences in prevalence based on geographical areas, laboratory methods used for diagnostics and structure of the tested feline population [13]. Cats can get infected by oral route with T. cati infective eggs from the environment, through lactogenic transmission of larvae from the queen to the kittens or by consumption of paratenic hosts, such as mice or birds, that contain somatic larvae [14]. Patent infections contribute to the environmental contamination through faeces, as hundreds of thousands of Toxocara spp. un-embryonated eggs per animal are released daily [15]. Besides the veterinary importance, T. cati represents a threat to public health, being able to cause human toxocariasis , a severe condition which has four major forms of development: visceral toxocariasis, neurotoxocariasis, ocular toxocariasis, and covert toxocariasis [16]. T. cati is less incriminated than T. canis , but its zoonotic potential should not be underestimated [17]. Humans can contaminate by ingesting embryonated eggs from the environment and consumption of unwashed fruits or vegetables and by ingesting infective larvae through consumption of raw meat [18,19]. T. cati may be an important soil-transmitted helminth especially in children. This can be due to the increased number of free-ranging cats and their behaviour of defecating near playgrounds, sandpits, and different urban outdoor public areas [20]. It is necessary to continuously assess the prevalence of zoonotic gastrointestinal parasites such as T. cati in domestic cats along with the parasitic contamination of the environment, to have a realistic picture regarding the risk for animal and public health. Also, epidemiological studies regarding correlations between clinical signs and involvement of enteropathogens such as T. cati are desirable in providing a better understanding of medical aspects among feline populations for veterinarians. In this frame, this study aimed to evaluate the prevalence of T. cati and other parasitic enteropathogens in cats with GI signs, but also to identify the risk factors associated with the parasitic infection. Results The age of the cats from this study was between 4 weeks and 15 years with an average of 26.03 ( ± 3.68) months; 66 (48.2%) cats were under 6 months old (2.96 ± 0.19 months), 39 (28.5%) were between 6 months and 2 years old (14.64 ± 1.18 months), and 32 (23.4%) individuals were over 2 years old (77.23 ± 8.19 months). The ratio between males and females was 1.05. Most of the cats were mixed breed (128/137). Ninety-six (70.1%) out of 137 cats had outdoor access, and only 74 (54.0%) cats were dewormed in the last three months. More than half (65.7%) of cats referred to our laboratory presented one or more digestive signs as vomiting ( n =21), diarrhoea ( n =78), or inappetence ( n =31). Digestive signs were more common in outdoor cats (78.8%), kittens (63.3%), and in un-dewormed cats (53.3%). Seventy-two (52.6%) out of 137 examined faecal samples from owned cats referred to our laboratory were positive for at least one GI parasite; they were significantly more common in cats with digestive symptoms ( n =61; 67.8%) than in clinically healthy ones ( n =11; 23.0%) (p<0.005). T. cati (40.2%) was significantly ( x 2 =131.14, p < 0.00001) the most frequently found GI parasite, followed by Cystoisospora spp. (10.2%), Aelurostrongylus abstrusus (4.4%), Ancylostoma tubaeforme (3.7%), Giardia duodenalis (2.2%), Taenia spp. (2.2%), Toxoplasma gondii -like (0.7%), and Capillaria aerophila (0.7%). Cystoisospora spp., G. duodenalis, and T. gondii -like were exclusively, and T. cati was predominantly identified in cats with digestive symptoms. Overall, and in cats with digestive signs single infection was significantly ( p < 0.00001) more prevalent than mixed infection (Table 1). Nevertheless, 14 out of 17 mixed infections were registered in symptomatic cats, and in 12 out of 17 mixed infections was involved T. cati. T. cati and Cystoiospora spp. was the most commonly found co-infection (5.8%) and the only one significantly involved in cats with digestive symptoms (8.9%, p<0.05). This association was registered only in outdoor cats and mainly in kittens (7/8) (unshown data). Lungworms A. abstrusus and C. aerophila in cats with digestive symptoms were identified in co-infection with T. cati (unshown data). Forty-eight (53.3%) out of 90 cats with digestive symptoms were infected with T. cati , and the prevalence was significantly higher ( p ˂0.00001) in symptomatic cats comparing with healthy ones (14.9%) (Table 1). According to the age category, 57.9% of kittens with digestive signs were infected with T. cati, 50.0% of young cats, and 36.4% of adult cats (Table 2). However, there was a decreasing trend of T. cati in symptomatic cats with age this was not statistically significant [ x 2 (2,90)=1.85, p =0.40]. Indoor and dewormed cats with digestive signs were less commonly infected with T. cati and the prevalence was not significantly different from those without clinical signs (Table 2). Table 1. Frequency, prevalence [ n (%)], and 95% confidence interval of GI parasites identified in owned cats with or without digestive symptoms Parasite Total ( n =137) Cats with digestive symptoms ( n =90) Clinically healthy cats ( n =47) P n (%) 95% CI n (%) 95% CI n (%) 95% CI T. cati 55 (40.2)*** 31.9-48.9 48 (53.3) 42.5-64.0 7 (14.9) 6.2-28.3 0.0000 Cystoisospora spp. 14 (10.2) 5.7-16.6 14 (15.6) 8.8-24.7 0 - 0.0009 G. duodenalis 3 (2.2) 0.5-6.3 3 (3.3) 0.7-9.4 0 - 0.1401 A. tubaeforme 5 (3.7) 1.2-8.3 4 (4.4) 1.2-11.0 1 (2.1) 0.1-11.3 0.2783 Taenia spp. 3 (2.2) 0.5-16.6 1 (1.1) 0.0-6.0 2 (4.3) 0.5-14.5 0.1547 T. gondii- like 1 (0.7) 0.0-4.0 1 (1.1) 0.0-6.0 0 - 0.3284 A. abstrusus 6 (4.4) 1.6-9.3 2 (2.2) 0.3-7.8 4 (8.5) 2.4-20.9 0.0615 C. aerophila 1 (0.7) 0.0-4.0 1 (1.1) 0.0-6.0 0 - 0.3284 Single infection 55 (40.1) 31.9-48.9 47 (52.2) 41.4-62.9 8 (17.0) 7.7-30.8 0.0000 Mixed infection 17 (12.4) 7.4-19.1 14 (15.6) 8.8-24.7 3 (6.4) 1.3-17.5 0.0635 Total 72 (52.6) 43.9-61.1 61 (67.8) 57.1-77.3 11 (23.0) 12.3-38.0 0.0000 Table 2. Prevalence of T. cati by each variable in cats with and without digestive symptoms (diarrhea, vomiting, and inappetence) Total (n=137) Cats with digestive symptoms ( n =90) Clinically healthy cats ( n =47) P n (%) 95% CI n (%) 95% CI n (%) 95% CI Age 2 years 6 (18.8) 7.2-36.4 4 (36.4) 10.9-69.2 2 (9.5) 1.2-30.4 0.05 Gender Females 30 (47.8) 32.6-57.4 26 (65.0) 48.3-79.4 4 (14.8) 4.2-33.7 0.0000 Males 25 (35.7) 24.6-48.1 22 (44.0) 30.0-58.8 3 (15.0) 3.2-37.9 0.01 Outdoor access Yes 53 (55.2)*** 44.7-65.4 46 (64.8) 52.5-75.8 7 (28.0) 12.1-49.4 0.0009 No 2 (4.9) 0.6-16.5 2 (10.5) 1.3-33.1 0 - 0.10 Dewormed in the last 3 months Yes 10 (13.5) 6.7-23.5 8 (19.1) 8.6-34.1 2 (6.3) 0.8-20.8 0.06 No 45 (71.4)*** 58.7-82.1 40 (83.3) 69.8-95.5 5 (33.3) 11.8-61.6 0.0002 * p ˂0.01; ** p ˂0.001; *** p > 0.0001 In kittens and young cats, diarrhoea (47/48) was significantly [ x 2 (2,144)=55.03, p <0.00001] the most frequent digestive symptom in cats infected with T. cati as unique (24/48) symptom or in combination (23/48) with other digestive symptoms [vomiting (12/48), and inappetence (22/48)] (Figure 1). Lack of deworming in the last three months (OR: 15.9), outdoor access (OR: 13.8), the presence of digestive symptoms (OR: 5.4), and young age (OR: 4.2) were identified as risk factors for T. cati infection in owned cats by logistic regression analysis (Table 3). Table 3. Risk factors for T. cati infection in domestic owned cats OR 95% CI p Age 0-24 months old 4.2 1.03 - 17.15 0.05 > 24 months old Ref. Gender Males 0.55 0.20 - 1.52 0.25 Females Ref. Outdoor access Yes 13.82 2.45 - 78.04 0.003 No Ref. Dewormed in the last 3 months No 15.85 5.43 - 46.24 0.00001 Yes Ref. Digestive symptoms No Ref. Yes 5.37 1.60 - 18.01 0.006 Discussion Gastrointestinal parasites are often diagnosed in companion animals; they affect the health and well-being of dogs and cats, and some of them are also of public health interest. Therefore, epidemiological studies are important in continuously updating data regarding prevalence and associated risk factors for parasitic diseases. Regardless of the presence or absence of digestive symptoms, the overall prevalence of GI parasites in owned cats from this study was high (52.6%), and four zoonotic parasites were identified ( Giardia spp., Toxoplasma -like, T. cati , and hookworms). T. cati was the most prevalent GI parasite (40.2%), and significantly more prevalent in symptomatic (53.3%), than in asymptomatic owned cats (14.9%). Different studies have been identified T. cati as the most frequently found parasite in domestic cats [13,24]. In Europe, T. cati prevalence varies between 7.2% and 83.3% with an average prevalence of 17.8% [11,24-26]. The prevalence of T. cati in household/owned and asymptomatic cats in Romania lies in the reported average for Europe according to this study and a previous one (20.3%) [27]. However, the prevalence of T.cati positive cats may differ depending on geographical regions, rural or urban areas, and exposure to risk factors. In western European countries are reported lower prevalences comparing with southern, central, and eastern European countries [24,25]. Numerous studies aimed to establish the correlation between exposure to different risk factors and infection with T. cati in cats. In the current study, outdoor access and lack of deworming were identified as the main risk factors, but also the age and presence of digestive clinical signs. Cats with outdoor access were 13.82 times more susceptible of being T. cati positive than indoor cats. This emphasizes the possibility of free-roaming and predatory behaviour significantly increasing the risk for infection also for cats with owners. This risk factor was assessed also by other authors [24,27,28] and a positive correlation was observed between the time a cat spends outdoor and the probability of a T. cati patent infection to occur [13]. Cats without an anthelmintic treatment in the last three months before sample collection were 15.9 more likely to be infected with T. cati. Prevalence of patent infection decreases if the frequency of anthelmintic treatment per year increases as shown in the study of Beugnet et al. [24]. Other studies did not find a positive association between patent T. cati infection and the time past from the last deworming of the cats, but suggest further investigations in this direction [13]. The European Scientific Council Companion Animal Parasites (ESCCAP) recommends a deworming frequency of four times a year and faecal examinations, but also a prevention and control management that can be adapted to individuals depending on exposure to risk factors. Kittens should start receiving deworming treatment every two weeks starting at three weeks of age until two weeks after weaning and monthly until they are six months. Moreover, for adult cats exposed to the infection through paratenic hosts from free roaming and outside access, a monthly treatment is recommended [29]. Cats of all ages are prone to patent infections with T. cati , therefore have the potential to be sources of contamination [30]. Nevertheless, in the current study, young age (0-2 years) represented a risk factor, with an increased rate of infection in kittens (51.5%). This is similar with the results obtain in other studies [13,27,31]. However, cats over 2 years should not be neglected as a potential reservoir for T. cati as the prevalence was still high (18.8%) probably due to the predatory behaviour of outdoor cats (40%) [30]. T. cati larvae that harbor in different tissues or organs of the paratenic hosts, such as small mammals or birds [32] once ingested by the definitive host, they develop and reach adult stages in the small intestines [17]. Gender was not found to be a risk factor and the same results were obtained by others [11,33]. Multiparasitism has significant relevance for the course of the disease, and also gives information about which antiparasitic medication should be chosen according to the cat’s age and risks of exposure. T. cati was found in 16 out of 17 cases of mixed infections, and the most prevalent mixed infection was between T. cati and Cystoisospora spp in outdoor kittens. Clinical signs are one of the main reasons of owners concerns and therefore for a vet consult. Few studies were made on correlations between gastrointestinal symptoms and various pathogens in feline populations. Their results are of both epidemiological and clinical importance since they can give the proper tools for veterinarians in establishing the most appropriate diagnostic and therapeutic protocols based on risk factors and clinical aspects of each individual. In this study, the involvement of parasites, especially of T. cati in cats with or without digestive symptoms was assessed. Parasitic pathogens were involved in a high percentage of cats with digestive symptoms (67.8%). Increased prevalence of parasites in cats with gastrointestinal symptoms was also found by others [34]. More than half of the cats (53.3%) that were brought with gastrointestinal signs were positive for T. cati infection. Contrary, in other studies Giardia spp. was more frequently found in cats with diarrheic faeces [6,34]. However, a higher prevalence of T. cati (5-30%) was found in unowned cats with diarrhoea coming from different settlements [35]. In this study, the presence of digestive symptoms and associated risk factors for feline toxocarosis (young age, outdoor access, lack of deworming) strongly suggests the infection with T. cati in cats. It was observed that regardless of the age of cats, diarrhoea can be significantly linked to T. cati patent infection. Besides the clinical and therapeutic implications that this correlation has, it can be assumed that zoonotic potential may be increased in cats with diarrhoea. A high prevalence of toxocarosis was seen also in cats with inappetence, therefore, this symptom can also be suggestive for T. cati . Furthermore, the involvement of the parasite increased with the number of associated digestive symptoms. Although age can be a risk factor, the implication of T. cati as a pathogen involved in digestive symptoms was not influenced by the cat’s age. That emphasizes that the parasite should not be excluded from the list of differential diagnoses in gastrointestinal disturbances even for older cats. An overall high percentage of parasitic pathogens were found in cats, but more importantly, in ones with digestive symptoms. Some of the identified parasites represent a concern in both animal and human health. Identifying correlations between patent infections with T. cati , clinical manifestations and various associated factors in cats is of real interest for establishing the proper diagnosis and developing efficient measures for treatment and control for feline infection, environmental contamination, and most importantly the zoonotic risk that this parasitic disease represents. The results of this study confirm the high rate of infection with T. cati and involvement of other parasitic enteropathogens in the aetiology of gastrointestinal symptoms in cats. Faecal testing is highly recommended as a routine examination in clinically healthy animals and as an important diagnostic tool in individuals with digestive signs, that could also reduce environment and human contamination. Materials and Methods Animals, samples, questionnaires, and samples analysis Over a three year period, 137 cats that were presented at the Emergency and Critical Care Department of the Veterinary Medicine Faculty were tested microscopically for intestinal parasites at the Parasitology and Parasitic Diseases Department (University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca – Faculty of Veterinary Medicine) for differential diagnosis or a periodical health check-up. Approximately 3-5 grams of faeces per sample were analysed using a flotation method in hypersaturated sodium chloride solution (sp. gr. 1.20) and examined after 30 minutes under a light microscope at a magnification of x10, x20, and x40 when necessary. Identification of parasitic elements (cysts, oocysts, eggs) was based on morphological characteristics [21,22]. Each cat owner received a questionnaire to fill in identification data for cats. The information was later used to assess possible risk factors that can influence the distribution of parasites:age, breed, and gender, the reason of presentation, digestive clinical signs, living condition (indoor, outdoor), and deworming status in the last three months. Statistical analysis Frequency, prevalence, and its 95% confidence interval were calculated for total infection, each parasite, co-infection, and studied variables. The variables were represented by age, gender, living condition, presence or absence of digestive signs, and deworming status. According to the age, cats were divided into three groups as follows: 0-6 months old (kittens), between 6 months and 2 years old (young cats), and over 2 years old (adult cats). Chi-square test was used to establish the differences in prevalence among studied variables. Risk factors associated with feline infection with T. cati were analysed by binary and multinomial logistic regression analysis. Statistical significance was established for a p -value equal to or less than 0.05. The statistical analysis was done with Epi Info TM 7 software (CDC, USA) [23]. Declarations Author Contributions: ALU conceptualization, data curation, formal analysis, investigation, methodology, writing - original draft & editing; AG data curation, statistical analysis, supervision, validation, visualization, writing - review & editing; VM data curation, validation; MOD writing - review & editing; ARC clinical examination, data and sample collection; VC supervision, validation. Funding: Institutional Review Board Statement: Not applicable. Informed Consent Statement: Not applicable. Data Availability Statement: Data sharing not applicable Acknowledgments: Not applicable. Conflicts of Interest: The authors declare no conflict of interest. References Barker, S.B.; Wolen, A.R. The benefits of human–companion animal interaction: A review. Med. Vet. 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Veterinary and public health aspects of Toxocara Vet. Parasitol. 2013 , 193 , 398-403, doi: 10.1016/j.vetpar.2012.12.035. Barutzki, D.; Schaper, R. Endoparasites in dogs and cats in Germany 1999–2002. Res. 2003 , 90 , S148-S150, doi: 10.1007/s00436-003-0922-6. Strube, C.; Heuer, L.; Janecek, E. 2013. Toxocara infections in paratenic hosts. Vet. Parasitol. 2013 , 193 , 375-389, doi: 10.1016/j.vetpar.2012.12.033. Zanzani, S.A.; Gazzonis, A.L.; Scarpa, P.; Berrilli, F.; Manfredi, M.T. Intestinal parasites of owned dogs and cats from metropolitan and micropolitan areas: prevalence, zoonotic risks, and pet owner awareness in northern Italy. BioMed Res. Int . 2014 , 2014, 1-10, 10.1155/2014/696508. López-Arias, Á.; Villar, D.; López-Osorio, S.; Calle-Vélez, D.; Chaparro-Gutiérrez, J.J. Giardia is the most prevalent parasitic infection in dogs and cats with diarrhea in the city of Medellín, Colombia. Parasitol. Reg. Stud. Reports 2019 , 18 , 100335, doi: 10.1016/j.vprsr.2019.100335. Andersen, L.A.; Levy, J.K.; McManus, C.M.; McGorray, S.P.; Leutenegger, C.M., Piccione, J.; Blackwelder, L.K. Tucker, S.J. Prevalence of enteropathogens in cats with and without diarrhea in four different management models for unowned cats in the southeast United States. J. 2018 , 236 , 49-55, doi: 10.1016/j.tvjl.2018.04.008. Cite Share Download PDF Status: Published Journal Publication published 13 Feb, 2021 Read the published version in Pathogens → Version 2 posted You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-153658","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":8899216,"identity":"160a09f6-d6cb-4954-96eb-a8493cd99c39","order_by":0,"name":"Aurora L. Ursache","email":"","orcid":"","institution":"University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Aurora","middleName":"L.","lastName":"Ursache","suffix":""},{"id":8899217,"identity":"d4480153-442d-4e3b-bd96-df1f9d36bd0e","order_by":1,"name":"Adriana Györke","email":"data:image/png;base64,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","orcid":"https://orcid.org/0000-0001-6453-2370","institution":"University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Adriana","middleName":"","lastName":"Györke","suffix":""},{"id":8899218,"identity":"66c22ca6-0fb6-40e3-bb40-02ade75459e6","order_by":2,"name":"Viorica Mircean","email":"","orcid":"","institution":"University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Viorica","middleName":"","lastName":"Mircean","suffix":""},{"id":8899219,"identity":"2ae5bd87-01aa-4730-a867-d5bd209a2f32","order_by":3,"name":"Mirabela Oana Dumitrache","email":"","orcid":"","institution":"University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Mirabela","middleName":"Oana","lastName":"Dumitrache","suffix":""},{"id":8899220,"identity":"1254f5f3-ccb5-48a1-8877-1897c11f7b3f","order_by":4,"name":"Andrei Răzvan Codea","email":"","orcid":"","institution":"University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Andrei","middleName":"Răzvan","lastName":"Codea","suffix":""},{"id":8899221,"identity":"57b5be04-3e38-40bb-9537-05560ae8b8f7","order_by":5,"name":"Vasile Cozma","email":"","orcid":"","institution":"University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Vasile","middleName":"","lastName":"Cozma","suffix":""}],"badges":[],"createdAt":"2021-01-23 05:47:30","currentVersionCode":2,"declarations":{"humanSubjects":false,"vertebrateSubjects":false,"conflictsOfInterestStatement":true,"humanSubjectEthicalGuidelines":false,"humanSubjectConsent":false,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":false,"coiExplicitlySet":false},"doi":"10.21203/rs.3.rs-153658/v2","doiUrl":"https://doi.org/10.21203/rs.3.rs-153658/v2","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.3390/pathogens10020198","type":"published","date":"2021-02-13T06:37:28+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":5285619,"identity":"1f0c5a93-c850-44c2-851a-e51dc4a74f7c","added_by":"auto","created_at":"2021-01-27 00:17:24","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":7367,"visible":true,"origin":"","legend":"Digestive clinical signs identified in owned cats infected with T. cati by age group (D – diarrhea; I – innapetence; V - vomiting)","description":"","filename":"1.png","url":"https://assets-eu.researchsquare.com/files/rs-153658/v2/9df9d79b672aea26892b0b9b.png"},{"id":59828101,"identity":"9aff9ec8-4b53-4657-9f72-6c51b5812ad8","added_by":"auto","created_at":"2024-07-08 06:37:33","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":776064,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-153658/v2/98b3249f-e423-4d71-b507-ca90fd924579.pdf"}],"financialInterests":"","formattedTitle":"\u003cp\u003e\u003cem\u003eToxocara cati \u003c/em\u003eand other parasitic enteropathogens: more commonly found in owned cats with gastrointestinal signs than in clinically healthy ones\u003c/p\u003e","fulltext":[{"header":"Introduction","content":"\u003cp\u003eIn the last years, the number of cats increased considerably in the urban areas worldwide. It is considered that the proven benefits of companion animals to the mental, emotional, and physical health of humans [1] might play an important role in this dynamic. By the year 2019, in Europe, approximately 106.4 million cats were estimated to be raised as pets and Romania is one of the countries with a considerable interest for feline companionship, with 47% of the households owning at least one cat [2,3]. Gastrointestinal disorders are a common concern of the owner when bringing the cat to the veterinary clinics for a health check-up [4,5]. The identification of the underlaying cause can be a challenge for clinicians, but it is desirable for an efficient and complete therapeutic protocol and management. Among dietary and stress-related problems or intestinal primary disorders, various pathogens such as viruses, bacteria, and parasites can be responsible for the development of gastrointestinal (GI) signs in companion animals [6,7]. Parasitic enteropathogens, both protozoa and helminths, are numerous and one of the causes for gastrointestinal disturbances expressed by diarrhoea, vomiting and/or changes in appetite [8,9], therefore faecal testing must be taken into consideration for differential diagnosis whenever digestive clinical signs are present [10]. Moreover, it is necessary to protect human-animal interaction by limiting the exposure to various infectious agents that can represent a risk to both cats and humans such as \u003cem\u003eToxocara cati\u003c/em\u003e, hookworms, \u003cem\u003eGiardia duodenalis\u003c/em\u003e, \u003cem\u003eToxoplasma gondii\u003c/em\u003e, \u003cem\u003eDipilidium caninum\u003c/em\u003e and \u003cem\u003eEchinoccocus multilocularis \u003c/em\u003e[11,12].\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eToxocara cati \u003c/em\u003eis a nematode frequently found in the intestine of domestic cats worldwide, with differences in prevalence based on geographical areas, laboratory methods used for diagnostics and structure of the tested feline population [13].\u003c/p\u003e\n\u003cp\u003eCats can get infected by oral route with \u003cem\u003eT. cati\u003c/em\u003e infective eggs from the environment, through lactogenic transmission of larvae from the queen to the kittens or by consumption of paratenic hosts, such as mice or birds, that contain somatic larvae [14]. Patent infections contribute to the environmental contamination through faeces, as hundreds of thousands of \u003cem\u003eToxocara\u003c/em\u003e spp. un-embryonated eggs per animal are released daily [15].\u003c/p\u003e\n\u003cp\u003eBesides the veterinary importance, \u003cem\u003eT. cati\u003c/em\u003e represents a threat to public health, being able to cause human toxocariasis\u003cem\u003e, \u003c/em\u003ea severe condition which has four major forms of development: visceral toxocariasis, neurotoxocariasis, ocular toxocariasis, and covert toxocariasis [16]. \u003cem\u003eT. cati\u003c/em\u003e is less incriminated than \u003cem\u003eT. canis\u003c/em\u003e, but its zoonotic potential should not be underestimated [17]. Humans can contaminate by ingesting embryonated eggs from the environment and consumption of unwashed fruits or vegetables and by ingesting infective larvae through consumption of raw meat [18,19]. \u003cem\u003eT. cati\u003c/em\u003e may be an important soil-transmitted helminth especially in children. This can be due to the increased number of free-ranging cats and their behaviour of defecating near playgrounds, sandpits, and different urban outdoor public areas [20].\u003c/p\u003e\n\u003cp\u003eIt is necessary to continuously assess the prevalence of zoonotic gastrointestinal parasites such as \u003cem\u003eT. cati\u003c/em\u003e in domestic cats along with the parasitic contamination of the environment, to have a realistic picture regarding the risk for animal and public health. Also, epidemiological studies regarding correlations between clinical signs and involvement of enteropathogens such as \u003cem\u003eT. cati\u003c/em\u003e are desirable in providing a better understanding of medical aspects among feline populations for veterinarians. In this frame, this study aimed to evaluate the prevalence of \u003cem\u003eT. cati\u003c/em\u003e and other parasitic enteropathogens in cats with GI signs, but also to identify the risk factors associated with the parasitic infection.\u003c/p\u003e"},{"header":"Results","content":"\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003eThe age of the cats from this study was between 4 weeks and 15 years with an average of 26.03 (\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: Symbol;\"\u003e\u0026plusmn;\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e3.68) months; 66 (48.2%) cats were under 6 months old (2.96\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: Symbol;\"\u003e\u0026plusmn;\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e0.19 months), 39 (28.5%) were between 6 months and 2 years old (14.64\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: Symbol;\"\u003e\u0026plusmn;\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e1.18 months), and 32 (23.4%) individuals were over 2 years old (77.23\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: Symbol;\"\u003e\u0026plusmn;\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e8.19 months). The ratio between males and females was 1.05. Most of the cats were mixed breed (128/137). Ninety-six (70.1%) out of 137 cats had outdoor access, and only 74 (54.0%) cats were dewormed in the last three months. More than half (65.7%) of cats referred to our laboratory presented one or more digestive signs as vomiting (\u003cem\u003en\u003c/em\u003e=21), diarrhoea (\u003cem\u003en\u003c/em\u003e=78), or inappetence (\u003cem\u003en\u003c/em\u003e=31). Digestive signs were more common in outdoor cats (78.8%), kittens (63.3%), and in un-dewormed cats (53.3%).\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003eSeventy-two (52.6%) out of 137 examined faecal samples from owned cats referred to our laboratory were positive for at least one GI parasite; they were significantly more common in cats with digestive symptoms (\u003cem\u003en\u003c/em\u003e=61; 67.8%) than in clinically healthy ones (\u003cem\u003en\u003c/em\u003e=11; 23.0%) (p\u0026lt;0.005). \u003cem\u003eT. cati \u003c/em\u003e(40.2%) was significantly (\u003cem\u003ex\u003c/em\u003e\u003csup\u003e2\u003c/sup\u003e=131.14, \u003cem\u003ep\u003c/em\u003e\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: Symbol;\"\u003e\u0026lt;\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e0.00001) the most frequently found GI parasite, followed by\u003cem\u003e Cystoisospora \u003c/em\u003espp. (10.2%), \u003cem\u003eAelurostrongylus abstrusus \u003c/em\u003e(4.4%), \u003cem\u003eAncylostoma tubaeforme \u003c/em\u003e(3.7%), \u003cem\u003eGiardia duodenalis \u003c/em\u003e(2.2%), \u003cem\u003eTaenia\u003c/em\u003e spp. (2.2%), \u003cem\u003eToxoplasma gondii\u003c/em\u003e-like (0.7%), and \u003cem\u003eCapillaria aerophila \u003c/em\u003e(0.7%). \u003cem\u003eCystoisospora \u003c/em\u003espp., \u003cem\u003eG. duodenalis, \u003c/em\u003eand \u003cem\u003eT. gondii\u003c/em\u003e-like were exclusively, and \u003cem\u003eT. cati was \u003c/em\u003epredominantly identified in cats with digestive symptoms. Overall, and in cats with digestive signs single infection was significantly (\u003cem\u003ep\u003c/em\u003e\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: Symbol;\"\u003e\u0026lt;\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e0.00001) more prevalent than mixed infection (Table 1). Nevertheless, 14 out of 17 mixed infections were registered in symptomatic cats, and in 12 out of 17 mixed infections was involved \u003cem\u003eT. cati. T. cati\u003c/em\u003e and \u003cem\u003eCystoiospora\u003c/em\u003e spp. was the most commonly found co-infection (5.8%) and the only one significantly involved in cats with digestive symptoms (8.9%, p\u0026lt;0.05). This association was registered only in outdoor cats and mainly in kittens (7/8) (unshown data). Lungworms \u003cem\u003eA. abstrusus \u003c/em\u003eand \u003cem\u003eC. aerophila\u003c/em\u003e in cats with digestive symptoms were identified in co-infection with \u003cem\u003eT. cati \u003c/em\u003e(unshown data).\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003eForty-eight (53.3%) out of 90 cats with digestive symptoms were infected with \u003cem\u003eT. cati\u003c/em\u003e, and the prevalence was significantly higher (\u003cem\u003ep\u003c/em\u003e˂0.00001) in symptomatic cats comparing with healthy ones (14.9%) (Table 1). According to the age category, 57.9% of kittens with digestive signs were infected with \u003cem\u003eT. cati, \u003c/em\u003e50.0% of young cats, and 36.4% of adult cats (Table 2). However, there was a decreasing trend of \u003cem\u003eT. cati \u003c/em\u003ein symptomatic cats with age this was not statistically significant [\u003cem\u003ex\u003c/em\u003e\u003csup\u003e2\u003c/sup\u003e(2,90)=1.85, \u003cem\u003ep\u003c/em\u003e=0.40]. Indoor and dewormed cats with digestive signs were less commonly infected with \u003cem\u003eT. cati \u003c/em\u003eand the prevalence was not significantly different from those without clinical signs (Table 2).\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: 150%;\"\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Times New Roman',serif;\"\u003eTable 1. \u003c/span\u003e\u003c/strong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Times New Roman',serif;\"\u003eFrequency, prevalence [\u003cem\u003en\u003c/em\u003e(%)], and 95% confidence interval of GI parasites identified in owned cats with or without digestive symptoms \u003c/span\u003e\u003c/p\u003e\n\u003ctable style=\"border-collapse: collapse; border: none; margin-left: 6.75pt; margin-right: 6.75pt;\" width=\"860\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.8pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 20.8pt;\" rowspan=\"2\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eParasite\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 141.75pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt; height: 20.8pt;\" colspan=\"2\" width=\"189\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eTotal \u003c/span\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e(\u003cem\u003en\u003c/em\u003e=137)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 177.15pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt; height: 20.8pt;\" colspan=\"2\" width=\"236\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eCats with digestive symptoms \u003c/span\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e(\u003cem\u003en\u003c/em\u003e=90)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 148.85pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt; height: 20.8pt;\" colspan=\"2\" width=\"198\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eClinically healthy cats \u003c/span\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e(\u003cem\u003en\u003c/em\u003e=47)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt; height: 20.8pt;\" rowspan=\"2\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.9pt;\"\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.9pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003en (%)\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.9pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e95% CI\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.9pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003en (%)\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.9pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e95% CI\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.9pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003en (%)\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.9pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e95% CI\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eT. cati\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e55 (40.2)***\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e31.9-48.9\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e48 (53.3)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e42.5-64.0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e7 (14.9)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e6.2-28.3\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.0000\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eCystoisospora \u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003espp.\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e14 (10.2)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e5.7-16.6\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e14 (15.6)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e8.8-24.7\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e-\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.0009\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eG. duodenalis\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e3 (2.2)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.5-6.3\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e3 (3.3)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.7-9.4\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e-\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.1401\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eA. tubaeforme\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e5 (3.7)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1.2-8.3\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e4 (4.4)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1.2-11.0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1 (2.1)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.1-11.3\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.2783\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eTaenia \u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003espp.\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e3 (2.2)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.5-16.6\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1 (1.1)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.0-6.0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e2 (4.3)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.5-14.5\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.1547\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 22.7pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 22.7pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eT. gondii-\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003elike\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 22.7pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1 (0.7)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 22.7pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.0-4.0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 22.7pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1 (1.1)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 22.7pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.0-6.0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 22.7pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 22.7pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e-\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 22.7pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.3284\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eA. abstrusus\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e6 (4.4)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1.6-9.3\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e2 (2.2)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.3-7.8\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e4 (8.5)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e2.4-20.9\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.0615\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eC. aerophila\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1 (0.7)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.0-4.0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1 (1.1)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.0-6.0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e-\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.3284\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eSingle infection\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e55 (40.1)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e31.9-48.9\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e47 (52.2)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e41.4-62.9\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e8 (17.0)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e7.7-30.8\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.0000\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eMixed infection\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e17 (12.4)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e7.4-19.1\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e14 (15.6)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e8.8-24.7\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e3 (6.4)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1.3-17.5\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.0635\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 17.2pt;\"\u003e\n\u003ctd style=\"width: 106.1pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"141\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eTotal\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 77.95pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e72 (52.6)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e43.9-61.1\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.4pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e61 (67.8)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 88.75pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"118\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e57.1-77.3\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 78.0pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"104\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e11 (23.0)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.85pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"94\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e12.3-38.0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 70.9pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 17.2pt;\" width=\"95\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.0000\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: 150%;\"\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eTable 2.\u003c/span\u003e\u003c/strong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e Prevalence of \u003cem\u003eT. cati \u003c/em\u003eby each variable in cats with and without digestive symptoms (diarrhea, vomiting, and inappetence) \u003c/span\u003e\u003c/p\u003e\n\u003ctable style=\"border-collapse: collapse; border: none;\" width=\"860\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" rowspan=\"2\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 170.1pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt;\" colspan=\"2\" width=\"227\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eTotal (n=137)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 163.0pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt;\" colspan=\"2\" width=\"217\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eCats with digestive symptoms \u003c/span\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e(\u003cem\u003en\u003c/em\u003e=90)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 155.95pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt;\" colspan=\"2\" width=\"208\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eClinically healthy cats \u003c/span\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e(\u003cem\u003en\u003c/em\u003e=47)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt;\" rowspan=\"2\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: center; line-height: normal;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003en (%)\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e95% CI\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003en (%)\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e95% CI\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003en (%)\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: 150%;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e95% CI\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 644.75pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" colspan=\"8\" width=\"860\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eAge\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e\u0026lt;6 months \u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e34 (51.5)**\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e38.9-64.0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e33 (57.9)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e44.1-70.9\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1 (11.1)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.3-48.3\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.006\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e6months-2years\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e15 (38.5)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e23.4-55.4\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e11 (50.0)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e28.2-71.8\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e4 (23.5)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e6.8-49.9\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.05\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e\u0026gt;2 years\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e6 (18.8)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e7.2-36.4\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e4 (36.4)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e10.9-69.2\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e2 (9.5)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1.2-30.4\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.05\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 644.75pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" colspan=\"8\" width=\"860\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eGender\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eFemales\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e30 (47.8)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e32.6-57.4\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e26 (65.0)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e48.3-79.4\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e4 (14.8)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e4.2-33.7\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.0000\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eMales\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e25 (35.7)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e24.6-48.1\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e22 (44.0)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e30.0-58.8\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e3 (15.0)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e3.2-37.9\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.01\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 644.75pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" colspan=\"8\" width=\"860\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eOutdoor access\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e53 (55.2)***\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e44.7-65.4\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e46 (64.8)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e52.5-75.8\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e7 (28.0)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e12.1-49.4\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.0009\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e2 (4.9)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.6-16.5\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e2 (10.5)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e1.3-33.1\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e-\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.10\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 644.75pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" colspan=\"8\" width=\"860\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eDewormed in the last 3 months\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e10 (13.5)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e6.7-23.5\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e8 (19.1)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e8.6-34.1\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e2 (6.3)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e0.8-20.8\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.06\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 91.9pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e45 (71.4)***\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 85.05pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"113\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e58.7-82.1\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 56.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"76\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e40 (83.3)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 106.3pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"142\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e69.8-95.5\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e5 (33.3)\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 92.15pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"123\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003e11.8-61.6\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 63.8pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt;\" width=\"85\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.0002\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"text-align: justify;\"\u003e\u003cspan style=\"letter-spacing: -0.1pt;\"\u003e*\u003c/span\u003e\u003cem\u003e\u003cspan style=\"letter-spacing: -.1pt;\"\u003ep\u003c/span\u003e\u003c/em\u003e\u003cspan style=\"letter-spacing: -.1pt;\"\u003e˂0.01; ** \u003cem\u003ep\u003c/em\u003e˂0.001; *** \u003cem\u003ep\u003c/em\u003e\u003c/span\u003e\u003cspan style=\"font-family: Symbol; letter-spacing: -.1pt;\"\u003e\u0026gt;\u003c/span\u003e\u003cspan style=\"letter-spacing: -.1pt;\"\u003e0.0001\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 107%; font-family: 'Calibri',sans-serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003eIn kittens and young cats, diarrhoea (47/48) was significantly [\u003cem\u003ex\u003c/em\u003e\u003csup\u003e2\u003c/sup\u003e(2,144)=55.03, \u003cem\u003ep\u003c/em\u003e\u0026lt;0.00001] the most frequent digestive symptom in cats infected with \u003cem\u003eT. cati \u003c/em\u003eas unique (24/48) symptom or in combination (23/48) with other digestive symptoms [vomiting (12/48), and inappetence (22/48)] (Figure 1). \u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003eLack of deworming in the last three months (OR: 15.9), outdoor access (OR: 13.8), the presence of digestive symptoms (OR: 5.4), and young age (OR: 4.2) were identified as risk factors for \u003cem\u003eT. cati \u003c/em\u003einfection in owned cats by logistic regression analysis (Table 3).\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; line-height: 150%;\"\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 150%; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Times New Roman',serif;\"\u003eTable 3.\u003c/span\u003e\u003c/strong\u003e\u003cspan style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Times New Roman',serif;\"\u003e Risk factors for \u003cem\u003eT. cati \u003c/em\u003einfection in domestic owned cats\u003c/span\u003e\u003c/p\u003e\n\u003ctable style=\"border-collapse: collapse; border: none;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eOR\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e95% CI\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border: solid windowtext 1.0pt; border-left: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cem\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003ep\u003c/span\u003e\u003c/em\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 462.75pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" colspan=\"4\" width=\"617\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eAge\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0-24 months old\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e4.2\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e1.03 - 17.15\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.05\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 12.45pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 12.45pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: Symbol;\"\u003e\u0026gt;\u003c/span\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e 24 months old\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 12.45pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eRef.\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 12.45pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 12.45pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 462.75pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" colspan=\"4\" width=\"617\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eGender\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eMales\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.55\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.20 - 1.52\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.25\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eFemales\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eRef.\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 462.75pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" colspan=\"4\" width=\"617\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eOutdoor access\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e13.82\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e2.45 - 78.04\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.003\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eRef.\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.85pt;\"\u003e\n\u003ctd style=\"width: 462.75pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.85pt;\" colspan=\"4\" width=\"617\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eDewormed in the last 3 months\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e15.85\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e5.43 - 46.24\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.00001\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eRef.\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 462.75pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" colspan=\"4\" width=\"617\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eDigestive symptoms\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003eRef.\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr style=\"height: 11.3pt;\"\u003e\n\u003ctd style=\"width: 115.65pt; border: solid windowtext 1.0pt; border-top: none; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; letter-spacing: -.1pt;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.65pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e5.37\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e1.60 - 18.01\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd style=\"width: 115.7pt; border-top: none; border-left: none; border-bottom: solid windowtext 1.0pt; border-right: solid windowtext 1.0pt; padding: 0in 5.4pt 0in 5.4pt; height: 11.3pt;\" width=\"154\"\u003e\n\u003cp style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif;\"\u003e0.006\u003c/span\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003eGastrointestinal parasites are often diagnosed in companion animals; they affect the health and well-being of dogs and cats, and some of them are also of public health interest. Therefore, epidemiological studies are important in continuously updating data regarding prevalence and associated risk factors for parasitic diseases. Regardless of the presence or absence of digestive symptoms, the overall prevalence of GI parasites in owned cats from this study was high (52.6%), and four zoonotic parasites were identified (\u003cem\u003eGiardia\u003c/em\u003e spp., \u003cem\u003eToxoplasma\u003c/em\u003e-like, \u003cem\u003eT. cati\u003c/em\u003e, and hookworms). \u003cem\u003eT. cati\u003c/em\u003e was the most prevalent GI parasite (40.2%), and significantly more prevalent in symptomatic (53.3%), than in asymptomatic owned cats (14.9%). Different studies have been identified \u003cem\u003eT. cati\u003c/em\u003e as the most frequently found parasite in domestic cats [13,24]. In Europe, \u003cem\u003eT. cati \u003c/em\u003eprevalence varies between 7.2% and 83.3% with an average prevalence of 17.8% [11,24-26]. The prevalence of \u003cem\u003eT. cati \u003c/em\u003ein household/owned and asymptomatic cats in Romania lies in the reported average for Europe according to this study and a previous one (20.3%) [27]. However, the prevalence of \u003cem\u003eT.cati\u003c/em\u003e positive cats may differ depending on geographical regions, rural or urban areas, and exposure to risk factors. In western European countries are reported lower prevalences comparing with southern, central, and eastern European countries [24,25].\u003c/p\u003e\n\u003cp\u003eNumerous studies aimed to establish the correlation between exposure to different risk factors and infection with \u003cem\u003eT. cati\u003c/em\u003e in cats. In the current study, outdoor access and lack of deworming were identified as the main risk factors, but also the age and presence of digestive clinical signs.\u003c/p\u003e\n\u003cp\u003eCats with outdoor access were 13.82 times more susceptible of being \u003cem\u003eT. cati\u003c/em\u003e positive than indoor cats. This emphasizes the possibility of free-roaming and predatory behaviour significantly increasing the risk for infection also for cats with owners. This risk factor was assessed also by other authors [24,27,28] and a positive correlation was observed between the time a cat spends outdoor and the probability of a \u003cem\u003eT. cati\u003c/em\u003e patent infection to occur [13]. Cats without an anthelmintic treatment in the last three months before sample collection were 15.9 more likely to be infected with \u003cem\u003eT. cati. \u003c/em\u003ePrevalence of patent infection decreases if the frequency of anthelmintic treatment per year increases as shown in the study of Beugnet et al. [24]. Other studies did not find a positive association between patent \u003cem\u003eT. cati\u003c/em\u003e infection and the time past from the last deworming of the cats, but suggest further investigations in this direction [13]. The European Scientific Council Companion Animal Parasites (ESCCAP) recommends a deworming frequency of four times a year and faecal examinations, but also a prevention and control management that can be adapted to individuals depending on exposure to risk factors. Kittens should start receiving deworming treatment every two weeks starting at three weeks of age until two weeks after weaning and monthly until they are six months. Moreover, for adult cats exposed to the infection through paratenic hosts from free roaming and outside access, a monthly treatment is recommended [29].\u003c/p\u003e\n\u003cp\u003eCats of all ages are prone to patent infections with \u003cem\u003eT. cati\u003c/em\u003e, therefore have the potential to be sources of contamination [30]. Nevertheless, in the current study, young age (0-2 years) represented a risk factor, with an increased rate of infection in kittens (51.5%). This is similar with the results obtain in other studies [13,27,31]. However, cats over 2 years should not be neglected as a potential reservoir for \u003cem\u003eT. cati \u003c/em\u003eas the prevalence was still high (18.8%) probably due to the predatory behaviour of outdoor cats (40%) [30]. \u003cem\u003eT. cati \u003c/em\u003elarvae that harbor in different tissues or organs of the paratenic hosts, such as small mammals or birds [32] once ingested by the definitive host, they develop and reach adult stages in the small intestines [17]. Gender was not found to be a risk factor and the same results were obtained by others [11,33].\u003c/p\u003e\n\u003cp\u003eMultiparasitism has significant relevance for the course of the disease, and also gives information about which antiparasitic medication should be chosen according to the cat\u0026rsquo;s age and risks of exposure. \u003cem\u003eT. cati\u003c/em\u003e was found in 16 out of 17 cases of mixed infections, and the most prevalent mixed infection was between \u003cem\u003eT. cati\u003c/em\u003e and\u003cem\u003e Cystoisospora\u003c/em\u003e spp in outdoor kittens.\u003c/p\u003e\n\u003cp\u003eClinical signs are one of the main reasons of owners concerns and therefore for a vet consult. Few studies were made on correlations between gastrointestinal symptoms and various pathogens in feline populations. Their results are of both epidemiological and clinical importance since they can give the proper tools for veterinarians in establishing the most appropriate diagnostic and therapeutic protocols based on risk factors and clinical aspects of each individual. In this study, the involvement of parasites, especially of \u003cem\u003eT. cati\u003c/em\u003e in cats with or without digestive symptoms was assessed. Parasitic pathogens were involved in a high percentage of cats with digestive symptoms (67.8%). Increased prevalence of parasites in cats with gastrointestinal symptoms was also found by others [34].\u003c/p\u003e\n\u003cp\u003eMore than half of the cats (53.3%) that were brought with gastrointestinal signs were positive for \u003cem\u003eT. cati\u003c/em\u003e infection. Contrary, in other studies \u003cem\u003eGiardia\u003c/em\u003e spp. was more frequently found in cats with diarrheic faeces [6,34]. However, a higher prevalence of \u003cem\u003eT. cati\u003c/em\u003e (5-30%) was found in unowned cats with diarrhoea coming from different settlements [35]. In this study, the presence of digestive symptoms and associated risk factors for feline toxocarosis (young age, outdoor access, lack of deworming) strongly suggests the infection with \u003cem\u003eT. cati\u003c/em\u003e in cats. It was observed that regardless of the age of cats, diarrhoea can be significantly linked to \u003cem\u003eT. cati\u003c/em\u003e patent infection. Besides the clinical and therapeutic implications that this correlation has, it can be assumed that zoonotic potential may be increased in cats with diarrhoea. A high prevalence of toxocarosis was seen also in cats with inappetence, therefore, this symptom can also be suggestive for \u003cem\u003eT. cati\u003c/em\u003e. Furthermore, the involvement of the parasite increased with the number of associated digestive symptoms. Although age can be a risk factor, the implication of \u003cem\u003eT. cati\u003c/em\u003e as a pathogen involved in digestive symptoms was not influenced by the cat\u0026rsquo;s age. That emphasizes that the parasite should not be excluded from the list of differential diagnoses in gastrointestinal disturbances even for older cats.\u003c/p\u003e\n\u003cp\u003eAn overall high percentage of parasitic pathogens were found in cats, but more importantly, in ones with digestive symptoms. Some of the identified parasites represent a concern in both animal and human health. Identifying correlations between patent infections with \u003cem\u003eT. cati\u003c/em\u003e, clinical manifestations and various associated factors in cats is of real interest for establishing the proper diagnosis and developing efficient measures for treatment and control for feline infection, environmental contamination, and most importantly the zoonotic risk that this parasitic disease represents.\u003c/p\u003e\n\u003cp\u003eThe results of this study confirm the high rate of infection with \u003cem\u003eT. cati\u003c/em\u003e and involvement of other parasitic enteropathogens in the aetiology of gastrointestinal symptoms in cats. Faecal testing is highly recommended as a routine examination in clinically healthy animals and as an important diagnostic tool in individuals with digestive signs, that could also reduce environment and human contamination.\u003c/p\u003e"},{"header":"Materials and Methods","content":"\u003cp\u003e\u003cstrong\u003e\u003cem\u003eAnimals, samples, questionnaires, and samples analysis \u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eOver a three year period, 137 cats that were presented at the Emergency and Critical Care Department of the Veterinary Medicine Faculty were tested microscopically for intestinal parasites at the Parasitology and Parasitic Diseases Department (University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca \u0026ndash; Faculty of Veterinary Medicine) for differential diagnosis or a periodical health check-up. Approximately 3-5 grams of faeces per sample were analysed using a flotation method in hypersaturated sodium chloride solution (sp. gr. 1.20) and examined after 30 minutes under a light microscope at a magnification of x10, x20, and x40 when necessary. Identification of parasitic elements (cysts, oocysts, eggs) was based on morphological characteristics [21,22].\u003c/p\u003e\n\u003cp\u003eEach cat owner received a questionnaire to fill in identification data for cats. The information was later used to assess possible risk factors that can influence the distribution of parasites:age, breed, and gender, the reason of presentation, digestive clinical signs, living condition (indoor, outdoor), and deworming status in the last three months.\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eStatistical analysis\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFrequency, prevalence, and its 95% confidence interval were calculated for total infection, each parasite, co-infection, and studied variables. The variables were represented by age, gender, living condition, presence or absence of digestive signs, and deworming status. According to the age, cats were divided into three groups as follows: 0-6 months old (kittens), between 6 months and 2 years old (young cats), and over 2 years old (adult cats). Chi-square test was used to establish the differences in prevalence among studied variables. Risk factors associated with feline infection with \u003cem\u003eT. cati\u003c/em\u003e were analysed by binary and multinomial logistic regression analysis. Statistical significance was established for a \u003cem\u003ep\u003c/em\u003e-value equal to or less than 0.05. The statistical analysis was done with Epi Info\u003csup\u003eTM\u003c/sup\u003e 7 software (CDC, USA) [23].\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eAuthor Contributions: \u003c/strong\u003eALU conceptualization, data curation, formal analysis, investigation, methodology, writing - original draft \u0026amp; editing; AG data curation, statistical analysis, supervision, validation, visualization, writing - review \u0026amp; editing; VM data curation, validation; MOD writing - review \u0026amp; editing; ARC clinical examination, data and sample collection; VC supervision, validation.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFunding:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eInstitutional Review Board Statement: \u003c/strong\u003eNot applicable.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eInformed Consent Statement: \u003c/strong\u003eNot applicable.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eData Availability Statement: \u003c/strong\u003eData sharing not applicable\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcknowledgments: \u003c/strong\u003eNot applicable.\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConflicts of Interest:\u003c/strong\u003e \u0026nbsp;The authors declare no conflict of interest.\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli\u003eBarker, S.B.; Wolen, A.R. The benefits of human\u0026ndash;companion animal interaction: A review. \u003cem\u003e Med. Vet. Educ.\u003c/em\u003e \u003cstrong\u003e2008\u003c/strong\u003e, \u003cem\u003e35\u003c/em\u003e, 487-496, doi:10.3138/jvme.35.4.487.\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.statista.com/statistics/516041/cat-population-europe-europe/\"\u003ehttps://www.statista.com/statistics/516041/cat-population-europe-europe/\u003c/a\u003e (accessed on October 28, 2020)\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.statista.com/statistics/515464/cat-ownership-european-union-eu-by-country/\"\u003ehttps://www.statista.com/statistics/515464/cat-ownership-european-union-eu-by-country/\u003c/a\u003e (accessed on 28 October, 2020)\u003c/li\u003e\n\u003cli\u003eLund, E.M.; Armstrong, P.J.; Kirk, C.A.; Kolar, L.M.; Klausnor, J.S. Health status and population characteristics of dogs and cats examined at private veterinary practices in the United States. \u003cem\u003e Am. Vet. Med. 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Reports\u003c/em\u003e \u003cstrong\u003e2019\u003c/strong\u003e, \u003cem\u003e18\u003c/em\u003e, 100335, doi: 10.1016/j.vprsr.2019.100335.\u003c/li\u003e\n\u003cli\u003eAndersen, L.A.; Levy, J.K.; McManus, C.M.; McGorray, S.P.; Leutenegger, C.M., Piccione, J.; Blackwelder, L.K. Tucker, S.J. Prevalence of enteropathogens in cats with and without diarrhea in four different management models for unowned cats in the southeast United States. \u003cem\u003e J. \u003c/em\u003e\u003cstrong\u003e2018\u003c/strong\u003e\u003cem\u003e, 236\u003c/em\u003e, 49-55, doi: 10.1016/j.tvjl.2018.04.008.\u003c/li\u003e\n\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"T. cati, enteropathogens, parasites, gastrointestinal signs, cats, risk factors","lastPublishedDoi":"10.21203/rs.3.rs-153658/v2","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-153658/v2","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eGastrointestinal parasites are involved in the health and wellbeing of cats and some of them, due to their zoonotic character represent a problem for the public health. This study aimed to assess the prevalence of parasitic infections in cats with digestive symptoms\u003cem\u003e.\u003c/em\u003e Faecal samples collected from 137 cats were analysed by the flotation method using sodium chloride saturated solution. The overall prevalence of gastrointestinal (GI) parasites was 56.6%. GI parasites were significantly (p=0.005) more common in cats with digestive symptoms (69.8%) than in clinically healthy ones (23.0%). \u003cem\u003eToxocara cati\u003c/em\u003e (40.2%) was the most frequently identified GI parasite, followed by \u003cem\u003eCystoisospora\u003c/em\u003e spp. (10.2%), \u003cem\u003eAncylostoma tubaeforme\u003c/em\u003e (3.7%), \u003cem\u003eTaenia\u003c/em\u003e spp. (2.2), \u003cem\u003eGiardia duodenalis\u003c/em\u003e (2.2%), and \u003cem\u003eToxoplasma gondii\u003c/em\u003e-like oocysts (0.7%). \u003cem\u003eT. cati\u003c/em\u003e (53.3%, \u003cem\u003ep\u003c/em\u003e\u0026lt;0.0001) and \u003cem\u003eCystoisospora\u003c/em\u003e spp. (15.6%, p\u0026lt;0.001) were significantly more frequently diagnosed in cats with digestive symptoms. Lack of deworming in the last three months (OR: 15.9), outdoor access (OR: 13.8), the presence of digestive symptoms (OR: 5.4), and young age (OR: 4.2) were identified as risk factors for \u003cem\u003eT. cati\u003c/em\u003e infection by logistic regression analysis. Regardless of the age, symptoms like vomiting, diarrhoea, and inappetence were positively associated with \u003cem\u003eT. cati\u003c/em\u003e.\u0026nbsp;\u003c/p\u003e\u003cp\u003e\u003cbr\u003e\u003c/p\u003e","manuscriptTitle":"Toxocara cati and other parasitic enteropathogens: more commonly found in owned cats with gastrointestinal signs than in clinically healthy ones","msid":"","msnumber":"","nonDraftVersions":[{"code":2,"date":"2021-01-27 00:17:22","doi":"10.21203/rs.3.rs-153658/v2","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}},{"code":1,"date":"2021-01-25 18:45:30","doi":"10.21203/rs.3.rs-153658/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"426522e0-486e-4d04-9487-9cf1094fd53b","owner":[],"postedDate":"January 27th, 2021","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":2051300,"name":"Parasitology"}],"tags":[],"updatedAt":"2024-07-08T06:37:28+00:00","versionOfRecord":{"articleIdentity":"rs-153658","link":"https://doi.org/10.3390/pathogens10020198","journal":{"identity":"pathogens","isVorOnly":true,"title":"Pathogens"},"publishedOn":"2021-02-13 06:37:28","publishedOnDateReadable":"February 13th, 2021"},"versionCreatedAt":"2021-01-27 00:17:22","video":"","vorDoi":"10.3390/pathogens10020198","vorDoiUrl":"https://doi.org/10.3390/pathogens10020198","workflowStages":[]},"version":"v2","identity":"rs-153658","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-153658","identity":"rs-153658","version":["v2"]},"buildId":"WrCJVZZCHTDjtuVLN7oU0","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}