STRyper: an open source macOS application for microsatellite genotyping

In the context of population genetics, microsatellite markers analyzed by capillary sequencing remain useful tools for quick genotyping and low-cost studies. This contrasts with the lack of a free application to analyze chromatograms for microsatellite genotyping that is designed for population geneticists. To fill this gap, I have developed STRyper, a macOS application whose source code is published under the General Public License. STRyper only uses macOS libraries, making it very lightweight, responsive, and behaving like a modern application. Its three-pane window enables easy management, searching and viewing of chromatograms imported from .fsa and. hid files, the creation of size standards and of microsatellite marker panels (including bins). The application has unique features allowing DNA ladder and genotype correction by drag-and-drop, and the management of variations in electrophoretic conditions. STRyper is available at https://github.com/jeanlain/STRyper.