The clinical value of serum CA125 in diagnosis of endometriosis caused pelvic pain

Ming Gao
In: Zhongguo jiceng yiyao · 2013 · vol. 20(09) , pp. 1304–1306 · doi:10.3760/cma.j.issn.1008-6706.2013.09.012 · W3031697798
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This study found that serum CA125 levels significantly correlate with the severity of endometriosis, increasing in stages III and IV compared to stages I and II.

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This retrospective study analyzed clinical data from 305 patients with endometriosis to evaluate the correlation between serum CA125 levels and disease staging according to the American Fertility Society classification. The results demonstrated that serum CA125 concentrations were significantly higher in stage III and IV cases compared to stages I and II, with positive rates increasing progressively across the stages. Although pain symptoms varied significantly among different stages, the study concluded that CA125 detection serves as a valuable tool for staging and assessing prognosis in these patients. This paper is centrally about endometriosis — specifically the diagnostic utility of serum CA125 levels in relation to disease stage and pelvic pain.

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Abstract

Objective To study the correlation of serum CA125 level and differentiation of endometriosis (EMs) and pelvic pain due to Ems.Methods The clincal data of 305 EMs patients were retrospectively analyzed,and they were divided into I,Ⅱ,Ⅲ,Ⅳ four stage according to r-AFS.The relevance of preoperative serum CA125 and differentiation of Ems and pelvic pain were assessed and statistically analyzed.Results The serum CA125 level was higher in Ⅲ,Ⅳ stage (69.4 ± 5.7) U/ml,(171 ± 11.5) U/ml than that in Ⅰ,Ⅱ stage (14.8 ± 1.2) U/ml,(36.3 ±3.0) U/ml,there was statistically significant difference (P ＜ 0.05).The positive rate of CA125 increased progressively (12.1％,21.5％,40.2％,63.9％),but the difference was not statistically significant(P ＞ 0.05).The pain syndromes in the clinical features of differentiation of Ems had obvious difference (P ＜ 0.05).Conclusion The serum CA125 detecting can be used in differentiation of Ems,and it has important value in diagnosis and prognosis of EMs. Key words: Cancer antigen 125 ;  Endometriosis
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血清糖类抗原125对子宫内膜异位症所致盆腔疼痛的诊断价值 The clinical value of serum CA125 in diagnosis of endometriosis caused pelvic pain 摘要目的 探讨血清糖类抗原125 (CA125)与子宫内膜异位症分期及盆腔疼痛的关系.方法 回顾性分析305例子宫内膜异位症患者的临床资料,根据美国生育学会制定的评分体系对子宫内膜异位症进行分期.统计不同分期患者术前血清CA125水平,评价术前血清CA125水平在子宫内膜异位症分期及临床特征的相关性.结果 Ⅲ、Ⅳ期子宫内膜异位症患者血清CA125水平(69.4±5.7) U/ml、(171 ± 11.5)U/ml,明显高于Ⅰ、Ⅱ期的(14.8±1.2) U/ml、(36.3±3.0) U/ml,差异均有统计学意义(P＜0.05).CA125阳性率在EMs分期中依次升高(12.1％、21.5％、40.2％、63.9％)；不同分期的疼痛症状差异有统计学意义(P＜0.05).结论 血清CA125检测可用于子宫内膜异位症的分期,在子宫内膜异位症的诊断、预后判断中具有重要的应用价值. 更多相关知识 abstractsObjective To study the correlation of serum CA125 level and differentiation of endometriosis (EMs) and pelvic pain due to Ems.Methods The clincal data of 305 EMs patients were retrospectively analyzed,and they were divided into I,Ⅱ,Ⅲ,Ⅳ four stage according to r-AFS.The relevance of preoperative serum CA125 and differentiation of Ems and pelvic pain were assessed and statistically analyzed.Results The serum CA125 level was higher in Ⅲ,Ⅳ stage (69.4 ± 5.7) U/ml,(171 ± 11.5) U/ml than that in Ⅰ,Ⅱ stage (14.8 ± 1.2) U/ml,(36.3 ±3.0) U/ml,there was statistically significant difference (P ＜ 0.05).The positive rate of CA125 increased progressively (12.1％,21.5％,40.2％,63.9％),but the difference was not statistically significant(P ＞ 0.05).The pain syndromes in the clinical features of differentiation of Ems had obvious difference (P ＜ 0.05).Conclusion The serum CA125 detecting can be used in differentiation of Ems,and it has important value in diagnosis and prognosis of EMs. More相关知识 - 浏览0 - 被引4 - 下载0 相似文献 - 中文期刊 - 外文期刊 - 学位论文 - 会议论文

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