Surface Plasmon Resonance (SPR) based biosensor using MXene as a BRE layer and Magnesium Oxide (MgO) as an Adhesion layer

Surface Plasmon Resonance (SPR) based biosensor using MXene as a BRE layer and Magnesium Oxide (MgO) as an Adhesion layer | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Surface Plasmon Resonance (SPR) based biosensor using MXene as a BRE layer and Magnesium Oxide (MgO) as an Adhesion layer AKASH SRIVASTAVA, Y.K. Prajapati This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-172711/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 08 Jul, 2021 Read the published version in Journal of Materials Science: Materials in Electronics → Version 1 posted You are reading this latest preprint version Abstract In this paper a plasmonic sensor consist of bimetallic layer of Ag and Au, a nono-thin layer of two dimension material MXene and a thin layer of Magnesium oxide (MgO) is proposed to operate in visible region. By using Kretschmann configuration based structure and transfer matrix method, the change in the refractive index of liquid Biosample have been observed at a fixed incident wavelength. By using the distinctive properties of Ti 3 C 2 T x MXene and MgO we have investigated the performance of Surface Plasmon Resoance (SPR) biosensor. Significant performance parameters like Sensitivity, Figure of Merit (FoM) and Detection Accuracy (DA) calculated for different cases to prove the capability of proposed sensing structure. We also compared the sensitivity and sharpness of SPR curve obtained when using conventional adhesion layers like titanium (Ti), chromium (Cr), tantalum (Ta). A detailed investigation is carried out to observe the role of polymer as an adhesion layer and its thickness impact on FoM and resonance angle sharpness. The concept of Long range SPR (LR-SPR) and Short range SPR (SR-SPR) also discussed. Electronic Materials and Devices Surface Plasmon Resonace (SPR) Oxide adhesion layer OSLR polymer Sensitivity Figure of Merit Long Range-SPR (LR-SPR) Figures Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Full Text Due to technical limitations, full-text HTML conversion of this manuscript could not be completed. However, the latest manuscript can be downloaded and accessed as a PDF. Cite Share Download PDF Status: Published Journal Publication published 08 Jul, 2021 Read the published version in Journal of Materials Science: Materials in Electronics → Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-172711","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":14256183,"identity":"fe25dec4-ba54-47c3-90e6-548a47c08048","order_by":0,"name":"AKASH SRIVASTAVA","email":"data:image/png;base64,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","orcid":"https://orcid.org/0000-0002-2085-8085","institution":"MNNIT Allahabad: Motilal Nehru National Institute of Technology","correspondingAuthor":true,"prefix":"","firstName":"AKASH","middleName":"","lastName":"SRIVASTAVA","suffix":""},{"id":14256184,"identity":"66cb0313-0325-463d-9265-871711416b0a","order_by":1,"name":"Y.K. Prajapati","email":"","orcid":"","institution":"Motilal Nehru National Institute of Technology","correspondingAuthor":false,"prefix":"","firstName":"Y.K.","middleName":"","lastName":"Prajapati","suffix":""}],"badges":[],"createdAt":"2021-01-28 10:29:22","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-172711/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-172711/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1007/s10854-021-06436-x","type":"published","date":"2021-07-08T15:01:21+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":6532721,"identity":"8508ec77-8313-4fd1-b7fc-a81a8d4ee07c","added_by":"auto","created_at":"2021-03-02 20:18:44","extension":"jpg","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":38320,"visible":true,"origin":"","legend":"Schematic diagram of proposed SPR based sensor","description":"","filename":"f1.jpg","url":"https://assets-eu.researchsquare.com/files/rs-172711/v1/4a223d1f6efa7a1cab8ae0cf.jpg"},{"id":6532589,"identity":"053b7e7e-6db8-4a27-9d0f-0d09d55f911d","added_by":"auto","created_at":"2021-03-02 20:15:44","extension":"jpg","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":83398,"visible":true,"origin":"","legend":"Adhesion layer effect of SPR based biosensor (a) comparison of SPR angle when MgO (oxide) used as a adhesion layer with metallic thin film based sensor (b) shift in resonance angle with and without using oxide adhesion layer","description":"","filename":"f2.jpg","url":"https://assets-eu.researchsquare.com/files/rs-172711/v1/6f305c90459cf031e675de1d.jpg"},{"id":6532722,"identity":"270b8f85-1fab-483c-ade3-6f4daca0b155","added_by":"auto","created_at":"2021-03-02 20:18:44","extension":"jpg","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":43852,"visible":true,"origin":"","legend":"variation of sensitivity with respect to analyte refractive index","description":"","filename":"f3.jpg","url":"https://assets-eu.researchsquare.com/files/rs-172711/v1/b5aad0ae2d6b98b0d251430c.jpg"},{"id":6532592,"identity":"9fc58890-7505-4f9d-a2db-ca53eae25910","added_by":"auto","created_at":"2021-03-02 20:15:44","extension":"jpg","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":41985,"visible":true,"origin":"","legend":"Limit of detection (LOD) variation with sugar concentration. Here the reference value of concentration from 0% ","description":"","filename":"f4.jpg","url":"https://assets-eu.researchsquare.com/files/rs-172711/v1/9bccc4129b130c7b3d0e3950.jpg"},{"id":6532595,"identity":"06e6d2d8-6f1a-4136-a545-4c41f4b8f4a0","added_by":"auto","created_at":"2021-03-02 20:15:45","extension":"jpg","order_by":5,"title":"Figure 5","display":"","copyAsset":false,"role":"figure","size":40508,"visible":true,"origin":"","legend":"modes of surface plasmon in Insulator metal insulator (IMI) type structure","description":"","filename":"f5.jpg","url":"https://assets-eu.researchsquare.com/files/rs-172711/v1/e27afeb264b76347c6bfb372.jpg"},{"id":6532594,"identity":"2ec27353-c7e5-4a21-862d-ef1ebeb5c0a9","added_by":"auto","created_at":"2021-03-02 20:15:44","extension":"jpg","order_by":6,"title":"Figure 6","display":"","copyAsset":false,"role":"figure","size":53338,"visible":true,"origin":"","legend":"resonance angle analysis for liquid analyte between C- SPR and LR-SPR","description":"","filename":"f6.jpg","url":"https://assets-eu.researchsquare.com/files/rs-172711/v1/253899912e0b9665a52a4990.jpg"},{"id":6532723,"identity":"7d7fcad8-b888-4302-81e7-696266dc7688","added_by":"auto","created_at":"2021-03-02 20:18:44","extension":"jpg","order_by":7,"title":"Figure 7","display":"","copyAsset":false,"role":"figure","size":76323,"visible":true,"origin":"","legend":"Polymer adhesion layer thickness dependent SPR angle(a) Resonance angle position by changing polymer layer thickness (b) performance parameter analysis","description":"","filename":"f7.jpg","url":"https://assets-eu.researchsquare.com/files/rs-172711/v1/5c4ef41caf0879a6d9e9d35d.jpg"},{"id":13673599,"identity":"8841c9e9-9cca-414a-aba3-a939ae89255d","added_by":"auto","created_at":"2021-09-17 11:18:09","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":445747,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-172711/v1/9cf6ed0b-2427-4ff6-9c91-e01d812241dd.pdf"}],"financialInterests":"","formattedTitle":"Surface Plasmon Resonance (SPR) based biosensor using MXene as a BRE layer and Magnesium Oxide (MgO) as an Adhesion layer","fulltext":[{"header":"Full Text","content":"Due to technical limitations, full-text HTML conversion of this manuscript could not be completed. However, the latest manuscript can be downloaded and \u003ca href='/article/rs-172711/latest.pdf' target='_blank'\u003e accessed as a PDF.\u003c/a\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":true,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Surface Plasmon Resonace (SPR), Oxide adhesion layer, OSLR polymer, Sensitivity, Figure of Merit, Long Range-SPR (LR-SPR)","lastPublishedDoi":"10.21203/rs.3.rs-172711/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-172711/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eIn this paper a plasmonic sensor consist of bimetallic layer of Ag and Au, a nono-thin layer of two dimension material MXene and a thin layer of Magnesium oxide (MgO) is proposed to operate in visible region. By using Kretschmann configuration based structure and transfer matrix method, the change in the refractive index of liquid Biosample have been observed at a fixed incident wavelength. By using the distinctive properties of Ti\u003csub\u003e3\u003c/sub\u003eC\u003csub\u003e2\u003c/sub\u003eT\u003csub\u003ex\u003c/sub\u003e MXene and MgO we have investigated the performance of Surface Plasmon Resoance (SPR) biosensor. Significant performance parameters like Sensitivity, Figure of Merit (FoM) and Detection Accuracy (DA) calculated for different cases to prove the capability of proposed sensing structure. We also compared the sensitivity and sharpness of SPR curve obtained when using conventional adhesion layers like titanium (Ti), chromium (Cr), tantalum (Ta). A detailed investigation is carried out to observe the role of polymer as an adhesion layer and its thickness impact on FoM and resonance angle sharpness. The concept of Long range SPR (LR-SPR) and Short range SPR (SR-SPR) also discussed.\u003c/p\u003e","manuscriptTitle":"Surface Plasmon Resonance (SPR) based biosensor using MXene as a BRE layer and Magnesium Oxide (MgO) as an Adhesion layer","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2021-03-02 20:15:39","doi":"10.21203/rs.3.rs-172711/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"91184b69-2f77-4037-9496-2d4c8ce55195","owner":[],"postedDate":"March 2nd, 2021","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":2721048,"name":"Electronic Materials and Devices"}],"tags":[],"updatedAt":"2021-08-17T16:09:25+00:00","versionOfRecord":{"articleIdentity":"rs-172711","link":"https://doi.org/10.1007/s10854-021-06436-x","journal":{"identity":"journal-of-materials-science-materials-in-electronics","isVorOnly":false,"title":"Journal of Materials Science: Materials in Electronics"},"publishedOn":"2021-07-08 15:01:21","publishedOnDateReadable":"July 8th, 2021"},"versionCreatedAt":"2021-03-02 20:15:39","video":"","vorDoi":"10.1007/s10854-021-06436-x","vorDoiUrl":"https://doi.org/10.1007/s10854-021-06436-x","workflowStages":[]},"version":"v1","identity":"rs-172711","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-172711","identity":"rs-172711","version":["v1"]},"buildId":"J0_U0BvcaRcwD8yVFaRlm","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}