Targeting the Warburg Effect with Glucosodiene: A Case Report of a 43-year-old Female after Mastectomy of the right breast and axillary clearance with Successful First Case Treatment for Metastatic Triple Negative Breast Cancer (TNBC) of Bone

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This case report details the treatment of a metastatic triple-negative breast cancer patient with glucosodiene, observing normal vital functions and no cellular activity after 15 days of treatment.

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AI-generated deep summary by claude@2026-07, 2026-07-14 · read from full text

This paper reports a single case of a 43-year-old woman with metastatic triple-negative breast cancer involving bone, treated after mastectomy and axillary clearance. The authors describe targeting the Warburg effect using glucosodiene, presenting this as a successful first-case treatment outcome. As a case report, the major limitation is the lack of a comparative study design and evidence generalizable beyond one individual. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Breast cancer is the most common type of cancer among women, and triple-negative breast cancer (TNBC) is a particularly aggressive subtype, representing 15-20% of cases. TNBC lacks estrogen, progesterone, and HER2 receptors, making it challenging to treat. This study explores a novel approach by investigating the metabolic pathways in TNBC, focusing on the alkaline glucose isomer, glucosodiene, as a potential therapy. The Warburg effect, discovered in 1924, serves as the basis for this investigation. The case report presents a 42-year-old female patient with TNBC Patient with MRM, Modified radical mastectomy, With axillary clearance., exhibiting a right breast lump with lymph node metastasis. Diagnostic tests confirmed invasive ductal carcinoma GII with negative hormone receptors and HER2/neu. The patient had previously undergone unsuccessful traditional chemotherapy and presented with bone metastasis. Treatment with glucosodiene for 15 days resulted in normal vital functions and no signs of cellular activity. This case study aims to evaluate an individualized treatment plan for TNBC patients and establish effective follow-up protocols. THE TRIAL IS REGISTERED UNDER CLINICALTRIALS.GOV NUMBER NCT05957939.
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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00
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