Endometrioid carcinoma of the ovary and endometriosis: the association in postmenopausal women

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Ovarian endometriosis was present in 26% of endometrioid carcinomas, particularly in postmenopausal women with Grade 1 or 2 tumors, suggesting a potential for malignant transformation.

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Abstract

Histologic material from 42 patients with endometrioid carcinomas of the ovary was reviewed. Ovarian endometriosis was present in 11 cases (26%) and 8 of these patients were postmenopausal. The exact site of transition from benign to malignant epithelium was observed in 4 cases. The clinical characteristics of patients with associated endometriosis were not significantly different from those without this finding except that endometriosis was present only in patients with Grade 1 or Grade 2 carcinomas. These data suggest that ovarian endometriosis in the postmenopausal patient has the potential to undergo malignant transformation and, when detected, should be removed surgically.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Endometriosis Menopause Ovarian Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma Adult Aged Aged, 80 and over Cell Transformation, Neoplastic Cell Transformation, Neoplastic Endometriosis Endometriosis Endometriosis Female Humans Middle Aged Ovarian Neoplasms Ovarian Neoplasms

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Source provenance

europepmc
last seen: 2026-09-04T06:17:57.233406+00:00
pubmed
last seen: 2026-05-13T22:11:44.647872+00:00
unpaywall
last seen: 2026-09-04T06:34:25.427880+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine