Expressions of Bcl-2 and PCNA in eutopic and ectopic human endometrium
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Bcl-2 protein staining was observed in glandular cells during the proliferative phase of eutopic endometrium, was absent during menstruation, and was highly expressed in endometriosis.
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Abstract
Objective To study the relation between bcl-2,proliferating cell nuclear antigen (PCNA) and endometrium and endometriosis. Methods The expressions of Bcl-2 and PCNA in eutopic endometrium from 46 cases during the menstrual cycle and ectopic endometrium from 15 patients with endometriosis were examined by immunohistochemical mothod. Results The staining of Bcl-2 protein on cytoplasm of glandular cells was mainly seen in proliferative phase. It rarely appeared in secretory phase and absent during menstruation. It appeared highly in endometriosis. Conclusion The expressions of Bcl-2 protein and PCNA protein in eutopic endometrium during the menstrual cycle have periodical changes ,and differ from that in endometriosis.
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- last seen: 2026-06-10T17:14:06.276822+00:00
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