ANIMAL MODEL AND METHOD FOR PRODUCING THE SAME

2007
OA: closed

Abstract

It is intended to provide an animal model which can reflect a lesion site of human endometriosis more faithfully, a method for producing the same, an animal model which enables noninvasive observation of a transplanted cell, and a method for producing the same. The animal model which has a uniform endometriosis lesion can be produced by introducing an expression vector containing a gene encoding an observation marker such as luciferase into a cell isolated from human, transplanting a cell which has come to express the observation marker under the renal capsule of an immunodeficient mouse such as an NOG mouse, and isolating the cell to be transplanted from the endometrium or a focal site of endometriosis.

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europepmc
last seen: 2026-07-08T06:14:57.058073+00:00