The effect of zataria multiflora on respiratory symptoms, pulmonary functions, and oxidative stress parameters: a systematic review and meta-analysis

Background: Zataria multiflora Boiss. is a medicinal plant with multiple pharmacological effects. This systematic review aims to review the available randomized controlled trials (RCTs) to assess the effects of zataria multiflora on respiratory symptoms, pulmonary function, and oxidative stress parameters. Materials & Methods We conducted a systematic review by searching the PubMed, Scopus, EMBASE, Cochrane Central for Randomized Clinical Trials. All statistical analyses were performed using STATA. Results Z. multiflora had a significant effect on cough, day wheezing, night wheezing and chest wheezing. Also, significantly improved FEV, FVC, MMEF, and PEF. In addition, significantly reduced MDA levels and increased CAT levels. Conclusion The meta-analysis showed that the consumption of ZT significantly reduced respiratory symptoms compared to the control group. Also, Zataria multiflora might be beneficial in improving pulmonary function. Except MDA, the result of this study indicated that Zataria multiflora did not have any significant effect on oxidative stress parameters.