Expression of CD_(44) in rat model with endometriosis

To study the expression of CD44 in rat model with endometriosis, CD44 in normal, eutopic and ectopic endometria from rat model of endometriosis were examined by immunohistochemical study and image analysis. There was no difference between the eutopic endometrial epithelial cells from rats models of endometriosis and the normal control rats models. The epithelial cells of ectopic endometrium from rats models of endometriosis showed a significant higher CD44 expression than eutopic endometrium of endometriotic rats. The abnormal expression of CD44 in ectopic endometria might play a significant role in the pathogenesis of endometriosis.