Risk Factors Influencing Cerebral Venous Infarction After Meningioma Resection

Abstract Introduction Cerebral venous infarction is a serious complication after meningioma resection. To reduce the incidence of venous infarction, we identified risk factors for postoperative cerebral venous infarction after surgical resection of meningioma in patients with clinical symptoms.Methods The clinical and imaging data of 1127 patients with intracranial meningiomas who underwent resection in our hospital were retrospectively collected and analyzed. Cerebral venous infarction was evaluated by postoperative imaging and clinical manifestations. Univariate and multivariate analyses were performed to identify risk factors associated with cerebral venous infarction.Results Overall, 3.3% (37/1127) of patients experienced symptomatic cerebral venous infarction after meningioma resection. Multivariate analysis revealed superficial meningioma, moderate to severe peritumoral edema, peritumoral critical vein and WHO grade II-III as independent predictors of a postoperative cerebral venous infarction. After timely intervention, the symptoms were clearly alleviated in one month, and the prognosis was good, but injury to key veins could cause irreversible neurological disorders.Conclusions Intraoperative protection of veins is the primary way to prevent cerebral venous infarction. The present study identified several significant and independent risk factors for postoperative venous infarction, thereby enabling the identification of high-risk patients who require special attention during clinical and surgical management.