Eisenmenger´s sydrome with complete AV septal defect in a 55-year-old woman

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This paper reports a clinical case of a 55-year-old woman with nonspecific atrioventricular septal defect (AVSD) diagnosed at 5 months of age after cardiac arrest, with progressive dyspnea and peripheral cyanosis leading to heart failure and pulmonary hypertension. The authors describe that at age 18, she was diagnosed with Eisenmenger’s syndrome due to complete AVSD, characterized by an ostium primum atrial septal defect, an inlet ventricular septal defect, and a common atrial-ventricular valve, and she was subsequently medicated to control pulmonary hypertension and cardiac failure. A key limitation is that this is a single preprint case report, with no broader study design or comparative analysis. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Nonspecific atrioventricular septal defect (AVSD) diagnosed at 5 months of age, after cardiac arrest. Progressive dyspnea, peripheral cyanosis, with development of heart failure and pulmonary hypertension. At 18 years, confirmation of Eisenmenger´s syndrome, (complete AVSD: ASD- ostium primum; inlet ventricular septal defect and common AV valve).  
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Eisenmenger´s sydrome with complete AV septal defect in a 55-year-old woman | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 3 September 2025 V2 Latest version Share on Eisenmenger´s sydrome with complete AV septal defect in a 55-year-old woman Authors : Ana Neves 0000-0002-5542-4412 [email protected] , Filipa Ferreira , and Helder Pereira Authors Info & Affiliations https://doi.org/10.22541/au.166075922.20208182/v2 475 views 135 downloads Contents Abstract Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Nonspecific atrioventricular septal defect (AVSD) diagnosed at 5 months of age, after cardiac arrest. Progressive dyspnea, peripheral cyanosis, with development of heart failure and pulmonary hypertension. At 18 years, confirmation of Eisenmenger´s syndrome, (complete AVSD: ASD- ostium primum; inlet ventricular septal defect and common AV valve). CLINICAL CASE REPORT Author - Dr.ª Ana Martins Neves (Internal Medicine) – Unidade Local Saúde Norte Alentejano (Portalegre) Title “Eisenmenger´s syndrome with complete AV septal defect in a 55-year-old woman“ Conflict of interests The authors whose names are listed immediately below certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript. Main author Dr.ª Ana Martins Neves (Internal Medicine) – Unidade Local Saúde Norte Alentejano (Portalegre) Other authors Dr. Filipa Ferreia (Cardiology) Hospital Garcia de Orta (Almada) Dr. Helder Pereira (Cardiology) Hospital Garcia de Orta (Almada) Written informed consent was obtained from the patient to publish this report in accordance with journal´s patient consent policy. Case report A nonspecific atrioventricular septal defect (AVSD) was diagnosed at 5 months of age, after cardiac arrest. Through the years, the patient showed progressive dyspnea, peripheral cyanosis, with development of heart failure and pulmonary hypertension. At 18 years, it was given the diagnosis of Eisenmenger´s syndrome, with a complete AVSD. This type of AVSD, is characterized by atrial septal defect (ADS)- ostium primum (Figure 1; 2); inlet ventricular septal defect (Figure 1; 2) and common atrial-ventricular valve (Figure 2; 3). Nowadays, the patient is medicated to control pulmonary hypertension and cardiac failure. Congenital malformations must be diagnosed early to avoid serious complications such as heart failure and pulmonary hypertension. That´s why it´s so important to detect and study early cardiorespiratory symptoms (cyanosis; dyspnea; heart murmurs). Doctors are responsible to care and to do their best to provide quality and a possibility to life with better conditions. We must be alert. Figure 1. Eisenmenger´s syndrome – Atrial septal defect (ASD) type “ostium primum” and inlet ventricular defect. Figure 2. Eisenmenger´s syndrome - ASD (“ostium primum”) and inlet ventricular defect Figure 3. Eisenmenger´s syndrome - complete atrioventricular septal defect with a common atrial-ventricular valve. Information & Authors Information Version history V1 Version 1 17 August 2022 V2 Version 2 03 September 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords cardiovascular disorders critical care medicine paediatrics and adolescent medicine Authors Affiliations Ana Neves 0000-0002-5542-4412 [email protected] Unidade Local de Saúde do Norte Alentejano EPE View all articles by this author Filipa Ferreira Hospital Garcia de Orta EPE View all articles by this author Helder Pereira Hospital Garcia de Orta EPE View all articles by this author Metrics & Citations Metrics Article Usage 475 views 135 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Ana Neves, Filipa Ferreira, Helder Pereira. Eisenmenger´s sydrome with complete AV septal defect in a 55-year-old woman. Authorea . 03 September 2025. DOI: https://doi.org/10.22541/au.166075922.20208182/v2 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. 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