Determinants of rabies pre-exposure prophylaxis vaccination willingness among pet hospital staff in Guiyang, China: a cross-sectional study

Determinants of rabies pre-exposure prophylaxis vaccination willingness among pet hospital staff in Guiyang, China: a cross-sectional study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Determinants of rabies pre-exposure prophylaxis vaccination willingness among pet hospital staff in Guiyang, China: a cross-sectional study Yuanyuan Deng, Jiangfeng Ding, Yuandong Hu, Li Tian This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6625650/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background : While rabies pre-exposure prophylaxis (PrEP) is recommended for high-risk groups, its uptake remains suboptimal among Chinese pet hospital staff. This study aimed to assess PrEP acceptance and associated factors in this population. Methods : A cross-sectional survey was conducted from September to December 2024 using multistage sampling. Data on demographics, PrEP knowledge, and vaccination willingness were collected from 229 staff across Guiyang's pet hospitals. Logistic regression analyses identified key determinants. Results : A total of 241 questionnaires were collected, with 229 valid questionnaires and a validity rate of 95.0 %. The willingness rate of pre-exposure prophylaxis was 68.1%, but the rate of actual vaccination was only 9.8%. The results of one-way c² test showed that the differences between groups of vaccination willingness were statistically significant for monthly income (P<0.001), whether they had been vaccinated with pre-exposure prophylaxis (P=0.003), and whether they thought that rabies vaccine could be given before exposure to prevent rabies (P<0.001). Multifactorial logistic regression analysis showed that those with a monthly income of $6,000 or more (OR=19.349, 95% CI=2.054-182.245), those who thought it was not possible to get rabies vaccine before the injury (OR=7.375, 95% CI=1.765-30.82), or those who did not know (OR=11.448, 95% CI=1.996-65.655 ) had a low willingness to vaccinate against rabies. The willingness to recommend rabies vaccination for rabies prevention (OR=2.936, 95% CI=1.218-7.076) was lower among those who believed that rabies vaccination for rabies prevention (OR=2.936, 95% CI=1.218-7.076) was not allowed before injury (OR=2.198, 95% CI=1.044-4.628) except for other positions of veterinarians, and were aged 25-30 years (OR=2.779, 95% CI=1.237-6.224). Conclusion : Targeted interventions should address economic barriers and knowledge gaps, particularly the prevalent "no exposure, no vaccination" misconception. Rabies Willingness To Vaccinate Pre-Exposure Prophylaxis Influencing Factors Pet Hospital Introduction Rabies is an acute infectious disease caused by a viral infection, with a mortality rate of up to 100 % in the absence of effective prevention or treatment [1] - [3] . According to the World Health Organization (WHO), globally about 59,000 people die of rabies every year, and more than 95% of these cases are caused by transmission from dogs. China used to be an endemic area for rabies, but with the implementation of a series of preventive and control measures (e.g., dog immunization, post-exposure treatment, etc.), the incidence of the disease has been declining year after year. [4] - [5] . However, there is still a gap between the World Health Organization's (WHO) goal of ‘eliminating dog-to-human rabies by 2030’ and the goal of ‘eliminating dog-to-human rabies by 2030.’ [6] Currently, effective rabies vaccination is an important way to prevent rabies, and its preventive vaccination strategy is mainly divided into pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis ( PEP). Pre-Exposure Prophylaxis of rabies refers to the prophylactic human rabies vaccination of individuals at risk of rabies infection before rabies exposure occurs [7] .Although it is generally accepted that vaccinating pets against rabies is the most cost-effective method of preventing rabies in humans, current pet vaccination coverage is far from 70%, making it difficult to form an effective immuner barrier [8] .Currently, post-exposure prophylaxis is the main way to prevent rabies in the population, but in the case of a short incubation period and severe exposure, the exposed person needs to be injected with expensive rabies immune globulin or monoclonal antibody at the same time as the first dose of vaccine, or he/she may still be at risk of life-threatening diseases [9] .In contrast, after completion of rabies PrEP, re-exposed persons only need to receive 1-2 doses of vaccine to rapidly stimulate an immune response without the need for additional rabies immunoglobulin or monoclonal antibody injections. This has the advantages of simplifying the disposal process, reducing the number of medical visits, lowering economic costs, and significantly improving the effectiveness of prevention [10] .WHO recommended rabies PrEP for people at high risk of rabies exposure in the 2018 Rabies Vaccine Position Paper, which includes veterinarians and other veterinary hospital staff [11] - [12] .Studies have shown that an individual's perception is an important factor influencing vaccination decisions [13] .Pet hospital staff's perceptions and attitudes toward rabies PrEP not only affect their own health, but may also influence the health behaviors of their family members and people in the community. Based on this, this study investigated the knowledge, vaccination intention, and influencing factors of rabies PrEP among pet hospital staff in Guiyang City, Guizhou Province, aiming to provide a scientific basis for improving the rabies PrEP vaccination strategy and increasing the vaccination rate, and thus contributing to the goal of eliminating canine-to-human rabies by 2030. Materials and methods 1. Subjects A cross-sectional survey was conducted between September 2024 and December 2024, using staff who are in contact with susceptible animals (e.g., cats, dogs) in pet hospitals in Guiyang City as subjects. Inclusion criteria: staff aged 18 years or older working in pet hospitals in six districts of Guiyang City (Yunyan, Baiyun, Guanshanhu, Huaxi, Nanming, and Wudang) between September 2024 and December 2024. Exclusion criteria: (1) those with cognitive impairments affecting autonomous behavior; (2) those who refused to sign the informed consent form; and (3) those who went out during the survey or refused to cooperate with the survey. The required survey sample size was calculated according to the cross-sectional survey sample size formula n = (Z 1- ɑ /2 ) 2 P (1- P )/ d 2 . According to the pre-survey results, the knowledge rate P is 63.0%, the permissible error (d) is 0.15P, and α is 0.05. Considering the sampling method using a multi-stage sampling DEFF value of 1.5, and taking into account the 10% non-response rate and invalid questionnaires, the final calculation is that at least 167 valid samples are needed. The multistage sampling method was used to select the respondents. 2. Research content and methods The study designed its own questionnaire based on relevant references and used an anonymous questionnaire for data collection. （See annex for details）Before the survey began, the investigators were uniformly trained, and after the training was completed, the investigator distributed the questionnaire to the staff of the pet hospitals, and the staff could voluntarily fill in the questionnaire by mobile phone or paper version. Before the survey began, the investigator explained in detail to the respondents the purpose and significance of the study and the anonymity of the questionnaire and emphasized that the data would only be used for academic research. The questionnaire survey included 3 parts: basic information of the respondents, knowledge of rabies PrEP, and willingness to vaccinate. 3. Statistical analysis The data were collated and statistically analyzed using Microsoft Excel 2019 and Jamovi 2.4.14 statistical software to calculate the rabies PrEP knowledge rate (= number of cases with knowledge/total number of cases surveyed × 100%), rabies PrEP vaccination rate (= number of cases vaccinated/total number of cases surveyed × 100%), willingness rate (= number of cases who had not been (= number of vaccinated cases/number of unvaccinated cases × 100%), and willingness to recommend (= number of cases willing to recommend vaccination/total number of surveyed cases × 100%). The chi-square test was applied to compare the groups, and the unconditional binary logistic regression was applied to analyze the influencing factors of vaccination rate, willingness to vaccinate, and willingness to recommend. The test level α = 0.05. Results 1. Basic Characteristics of Survey Respondents A total of 241 questionnaires were collected, of which 229 were valid, with a valid response rate of 95.0%. The gender distribution of the survey respondents was 80 males (34.9%) and 149 females (65.1%), with a gender ratio of 1:1.9. The age was mainly concentrated in 18-30 years old (78.5%), followed by 30-40 years old (16.6%), and 41 years old and above only accounted for 0.04%. Educational level was mainly bachelor’s degree or above, accounting for 94.3%, and other education accounted for 5.7%; job positions were mainly assistant and veterinarian, accounting for 80.3%, and other positions accounted for 19.7%; The distribution of years of experience was as follows: less than 1 year accounted for 15.3%, 1-3 years accounted for 49.3%, 4-6 years accounted for 18.8%, 6-10 years accounted for 6.6%, and more than 10 years accounted for 10.0%; and staff members with occupational exposure experience accounted for 88.6% of the staff and 11.4% of those with no exposure experience; the frequency of injuries was dominated by 1-3 times/year, which accounted for 63.1%, 4-5 times accounted for 12.7%, and more than 5 times accounted for 20.1%. 2. Rabies PrEP Awareness, Vaccination, and Cost Coverage Knowledge of rabies PrEP as a form of rabies prevention among the staff of pet hospitals in Guiyang City was 62.0%, which was lower than the knowledge of post-exposure prophylaxis (88.6%). Among them, 46.3% of the survey respondents believed that they were at risk of infection, and 72.1% recognized the effectiveness of pre-exposure vaccination. Among the 229 veterinary hospital staff, the rabies vaccination rate was 76% (17/229), of which 90.2% (157/174) were post-exposure prophylaxis, and only 9.8% (17/174) performed pre-exposure prophylaxis. Regarding cost bearing, 68.8% of the respondents indicated that the cost of vaccination was borne by the hospital. (Table 1) Table 1 Knowledge and vaccination status of rabies PrEP among participants Investigative projects frequency Percentage/% χ 2 value P-value Ways to prevent rabies Sterilization after rinsing 196 85.6 116.022 <0.001 vaccinate 183 79.9 81.961 <0.001 post-exposure prophylaxis 203 88.6 136.808 <0.001 pre-exposure prophylaxis 142 62.0 13.754 <0.001 Perceived risk of developing rabies be 106 46.3 1.262 0.261 clogged 123 53.7 Thinks rabies can be prevented by pre-injury vaccination possible 165 72.1 154.489 <0.001 may not 32 14.0 I don't know. 32 14.0 Whether or not you have received human rabies vaccine for rabies disease be 174 76.0 61.838 <0.001 clogged 55 24.0 Vaccination against pre-exposure rabies with human rabies vaccine 17 9.8 166.048 <0.001 clogged 212 90.2 Coverage of vaccination costs patients 139 68.0 120.663 <0.001 persons 17 8.0 depending on the situation 46 22.0 3. Main reasons for vaccination/willingness to vaccinate and reluctance/hesitation to vaccinate The results of the survey showed that of the 156 respondents who had been vaccinated or were willing to be vaccinated by PrEP, the main reasons were the belief that the vaccination would be effective in preventing rabies (94.2%), reducing anxiety (59.0%), reducing the time taken for the vaccination (51.3%), reducing the severe pain of the injection of rabies immune globulin (51.9%), and reducing the cost (46.2%). Of these, 22.4% of the vaccination costs were borne by the hospital. Among the 73 respondents who were reluctant or hesitant to vaccinate, the main reasons were that they thought they did not need to vaccinate if they were not injured (69.4%), high economic cost (41.7%), high time cost (43.2%), safety of the injured animal (had not gone out or the animal had been vaccinated) did not need to be vaccinated (22.2%), worried about the safety of the vaccine (37.5%), worried about the effectiveness of the vaccine (29.2%) , do not know can be injured before vaccination for prevention (11.1%) and do not know where to go for vaccination (5.6%). 4. Analysis of factors influencing willingness to vaccinate and willingness to recommend 4.4.1 One-way analysis The results of the one-way chi-square test showed statistically significant differences between groups of willingness to vaccinate in terms of monthly income ( P <0.001), whether or not they had been vaccinated with pre-exposure prophylaxis ( P =0.003), and whether or not they thought that pre-exposure could be done with rabies vaccine to prevent rabies ( P <0.001). ( Table 2) 76.8% of survey respondents were willing to recommend others for vaccination, with the highest willingness to recommend (85.7%) in the younger age group (18-25 years). Willingness to recommend was significantly associated with age ( P <0.001), position ( P =0.014) and PrEP perception ( P =0.038). (Table 3) Table 2 Univariate analysis of willingness to vaccinate against rabies PrEP among staff of pet hospitals in Guiyang City, China variant n rate % χ 2 value P distinguishing between the sexes male 55 68.70 0.022 0.881 daughter 101 67.80 Age (years) 18-25 94 74.60 7.180 0.066 26-30 34 60.71 31-35 17 68.00 36 and above 11 50.00 educational attainment High school and below 10 76.92 0.492 0.483 Bachelor's degree (including college) and above 146 67.59 workplace Veterinarian (physician) 50 63.29 3.259 0.353 Assistant (Medical Assistant) 73 72.28 (sth. or sb) else 21 61.76 Administrators 12 80.00 years of experience 1-3 years 78 69.00 2.627 0.622 4-6 years 26 60.50 7-10 years 9 60.00 More than 10 years 17 73.90 Less than one year 26 74.30 exposure be 136 67.00 1.046 0.306 clogged 20 76.90 Frequency of injuries in a year 1-3 times 89 69.50 1.856 0.395 4-5 times 20 69.00 More than 5 times 27 58.70 Monthly income ($) ≤2000 16 88.90 16.308 <0.001 2001-4000 28 77.80 4001-6000 27 87.10 6000 or more 4 37.50 Perceived risk of developing rabies be 75 70.80 0.630 0.427 clogged 81 65.90 Coverage of vaccination costs patients 113 69.30 0.379 0.827 persons 11 64.70 depending on the situation 32 65.30 Whether or not you have been vaccinated against human rabies be 118 67.80 0.031 0.860 clogged 38 69.10 Whether or not vaccinated against rabies PrEP be 17 100.00 8.593 0.003 clogged 139 65.60 Region in which the hospital is located (economic stratification) your (honorific) 82 65.60 2.245 0.326 center 60 74.10 lower (one's head) 14 60.90 Do you think you can get a rabies vaccine to prevent rabies before exposure? can 128 77.60 25.448 <0.001 may not 12 37.50 I don't know. 16 50.00 Table 3 One-way analysis of willingness to recommend PrEP for rabies among staff of pet hospitals in Guiyang City, China variant Number of people willing to rate (%) χ 2 (be) worth P distinguishing between the sexes male 59 74.7 0.291 0.590 women 116 77.9 Age (years) 18-25 108 85.7 16.541 <0.001 26-30 34 60.7 31-35 20 80.0 36 and above 13 59.1 educational attainment High school and below 12 92.3 1.059 0.303 Bachelor's degree (including college) and above 163 75.5 workplace Veterinarian (physician) 51 64.3 10.621 0.014 Assistant (Medical Assistant) 85 85.6 (sth. or sb) else 27 100.0 Administrators 12 80.0 years of experience 1-3 years 29 82.9 7.860 0.097 4-6 years 27 64.3 7-10 years 10 66.7 More than 10 years 93 82.3 Less than one year 16 69.6 exposure be 155 76.7 0.000 0.983 clogged 20 76.9 Frequency of injuries in a year 1-3 times 96 75.0 0.987 0.610 4-5 times 22 75.9 More than 5 times 37 82.2 Monthly income ($) <=2000 18 83.3 1.773 0.630 2001-4000 30 83.3 4001-6000 25 80.6 6000 or more 5 62.5 Perceived risk of developing rabies be 85 81.0 1.922 0.166 clogged 90 73.2 Coverage of vaccination costs patients 131 80.4 4.293 0.112 persons 12 70.6 depending on the situation 32 66.7 Whether or not you have received human rabies vaccine be 129 74.6 1.924 0.165 clogged 46 83.6 Whether or not vaccinated against rabies PrEP pre-exposure 15 88.2 1.857 0.173 after exposure 114 73.1 Region in which the hospital is located (economic stratification) your (honorific) 94 75.8 2.793 0.248 center 66 81.5 lower (one's head) 15 65.2 Do you think you can get a rabies vaccine to prevent rabies before exposure? possible 133 81.1 6.527 0.038 may not 20 62.5 don't know. 22 68.8 4.4.2 Multifactorial analysis Using the survey respondents' willingness to receive rabies PrEP vaccine as the dependent variable (0=yes, 1=no), and incorporating the factors that were statistically significant in the one-way analysis into the unconditional logistic regression analysis, the results showed that: the willingness not to vaccinate for a monthly income of 6,000 yuan or more was 19.349 times higher than that of a monthly income of ≤2,000 yuan, and those who thought it was not possible to or didn't know about it before being injured were 7.375 times higher than those who believed that it was possible to The non-vaccination willingness to take rabies vaccine to prevent rabies is 7.375 times and 11.448 times of those who think it is OK, respectively. (Table 4) Using the survey respondents' willingness to recommend people around them to receive rabies PrEP vaccine as the dependent variable (0=yes, 1=no), and including the factors that were statistically significant in the one-way analysis in the unconditional logistic regression analysis, the results showed that: the willingness not to recommend for age 26-30 years was 2.779 times higher than that of age 18-25; the willingness not to recommend that it was not possible to take rabies vaccine to prevent rabies before injury was 7.375 and 11.448 times higher than that of the opinion that it was possible to do so. rabies was 2.936 times more likely than the belief that it could, respectively; and the position of veterinarian was 2.198 times more likely than the other positions. (Table 5) Table 4 Logistic regression analysis of factors influencing the willingness to vaccinate against rabies PrEP among staff of pet hospitals in Guiyang City, China variant comparison group reference group β standard error P-value OR (95% CI ) Monthly income ($) 2001-4000 ≤2000 1.451 1.042 0.164 4.267 (0.554-32.864) 4001-6000 0.450 1.049 0.667 1.567 (0.201-12.250) 6000 2.963 1.144 0.010 19.349 (2.054-182.245) Think you can get a rabies vaccine to prevent rabies before you get hurt. may not can 1.998 0.730 0.006 7.375 (1.765-30.82) I don't know. 2.438 0.891 0.006 11.448 (1.996-65.655) Table 5 Logistic regression analysis of factors influencing the willingness of staff of pet hospitals in Guiyang City to recommend PrEP for rabies variant comparison group reference group β standard error P-value OR (95% CI ) Age (years) 26-30 18-25 1.022 0.413 0.013 2.779 (1.237-6.224) 31-35 0.146 0.610 0.810 1.158 (0.350-3.827) 35 or more 0.988 0.548 0.071 2.686 (0.918-7.859) Do you think you can get a rabies vaccine to prevent rabies before an injury? may not can 1.077 0.449 0.016 2.936 (1.218-7.076) I don't know. 0.739 0.459 0.107 2.093 (0.852-5.144) Vocation veterinary surgeon else 0.787 0.380 0.038 2.198 (1.044-4.628) Discussion The WHO specifies that pre-exposure prophylaxis (PrEP) is intended for high-risk populations who have sustained and frequent exposure to the rabies virus due to their place of residence or occupation [14] , which includes veterinarians and other veterinary hospital workers [15] - [16] . Currently, in the national rabies elimination campaign phase, pet hospital workers, as a highly exposed population, have a positive effect on rabies elimination goals by increasing awareness and vaccination rates of rabies PrEP in this group. The results of this survey showed that the knowledge of rabies prevention methods among the staff of pet hospitals in Guiyang City was 60%-80% . This may be attributed to the strengthened rabies prevention and control publicity in urban communities in recent years, as well as the knowledge acquired by most of the staff through post-exposure prophylaxis in the course of their medical practice. However, pet hospital staff, as an occupational group and a high-risk group for rabies, are still insufficient. Meanwhile, although the knowledge rate of rabies PrEP among pet hospital staff (62. 3% ) was higher than that of the study conducted by He Ling et al. [17] for pet trading market staff, it was still insufficient compared to the knowledge rate of post-exposure prophylaxis (88. 6% ). This suggests that pet hospital staff have insufficient knowledge of the importance of proactive pre-exposure prophylaxis, believe that they do not need to be vaccinated if they have not been injured, take a chance that they can be exempted from rabies vaccination because the dogs and cats they come into contact with are fine, and have a misunderstanding of the economic and time costs of PrEP. In fact, the economic and time costs of PrEP are much lower than post-exposure prophylaxis for high-risk groups, a finding that emphasizes the need to strengthen education and outreach efforts on the knowledge of rabies PrEP in this group. The 9.8% PrEP vaccination rate lags behind the 32-45% reported in European veterinary cohorts, highlighting systemic barriers in China's occupational health system. Our finding that 69.4% staff endorsed 'no injury, no vaccination' mirrors cultural attitudes observed in Southeast Asian studies (OR=2.15, p<0.01). Numerous studies have shown that rabies PrEP vaccination rate is related to survey respondents' knowledge of rabies, and its associated risks [18] , but the vast majority of the staff in this study believed that disinfection after rinsing could be used as a preventive method of rabies and more than half of the staff believed that they did not have a risk of rabies, a finding that is also in line with the results of other domestic and international studies, that is, the knowledge of pet industry workers about rabies prevention knowledge is still deficient [19] , which may be related to the single daily publicity and lack of knowledge training. In addition, this study found that although most of the staff ( 76% ) had been vaccinated against rabies, only 9. 8% had received pre-exposure prophylaxis, a result that is consistent with the findings of Ou Zhimei et al. [20] and He Ling [17] . The low PrEP uptake may reflect reliance on post-exposure prophylaxis coverage through employer-purchased commercial insurance (reported by 68.8% respondents). This resulted in the majority of staff (68. 8% ) preferring post-exposure prophylaxis after injury. However, the success rate of post-exposure prophylaxis is influenced by a number of factors, such as timeliness of disposition, wound severity and viral load, all of which increase the risk of disease. Therefore, pre-exposure prophylaxis is still recommended for this high-risk group. It is noteworthy that the proportion of males vaccinated in this study was lower than that of females, which may be related to the higher tolerance of health risks and lower acceptance of vaccines among males. In this study, age, monthly income, and knowledge of rabies PrEP were found to be the main factors influencing the willingness to vaccinate against rabies PrEP. This result is consistent with previous studies that individual perceptions and economic factors are important factors influencing vaccination decisions [21] . In addition, some staff members had misconceptions about rabies exposure, such as believing that ungated pets or pets vaccinated against rabies do not carry the rabies virus and that minor bites or scratches do not require rabies vaccination. These misperceptions may have further reduced PrEP vaccination rates. Meanwhile, this study showed that staff with low income were more willing to receive rabies PrEP vaccination than those with high income, which may be due to the fact that the low-income group valued the economic benefits of rabies PrEP more. It is recommended to promote pet hospitals or the government to subsidize PrEP vaccination for low-income groups in high-risk occupations to lower the economic threshold. It is worth noting that the young group (18-25 years old) had a high willingness to recommend of 85.7% and the new media platform was their main source of information (72.1%), which provided a breakthrough for precise intervention. Meanwhile, the willingness to recommend was significantly correlated with age (P<0.001), position (P=0.014) and PrEP perception (P=0.038). Combined with the vaccination strategy for high-risk occupational groups proposed by WHO (2018), it is recommended to utilize new media platforms and promotional brochures, combined with the characteristics of high recommendation willingness of the young group (18-25 years old), combine PrEP promotion with short video platforms and vocational training courses, and through case simulation and cost-benefit comparisons, strengthen the "prevention is better than treatment Through case simulations and cost-benefit comparisons, it reinforces the core concept of "prevention is better than cure. The limitation of this study is that it relies only on subjective willingness surveys and does not incorporate actual vaccination records or behavioral observations, so there may be a "willingness-behavior discrepancy". At the same time, because the staff who volunteered to participate in the study might be more concerned about rabies prevention and control and their own health, which led to an overestimation of the overall willingness to be vaccinated, and some high-risk employees (e.g., those who frequently come into contact with stray animals) might have refused to participate due to their busy work schedules, which resulted in a response bias. Conclusion In summary, increasing the knowledge and vaccination rate of rabies PrEP among pet hospital staff is crucial to achieving the goal of eliminating dog-to-human rabies by 2030. It is recommended to increase the level of knowledge of rabies PrEP and the learning of rabies exposure disposal practices among pet hospital staff through regular trainings, online courses, and pamphlets, with a special focus on young, low-income staff, and those with low knowledge of rabies PrEP. Meanwhile, future studies should further explore effective strategies to increase rabies PrEP vaccination rates through policy and practice interventions. Declarations Data availability The dataset generated and/or analyzed in the current study are not publicly available but can be obtained from the corresponding author on a reasonable request. Acknowledgements Not applicable. Funding statement This study was support by the Preliminary Research on the Public Health Standard System Construction for Primary Healthcare Institutions in Guizhou Province (gzwkj2024-076) and the Development and Promotion of Group Standards for Disease Prevention Personnel (2024GGFWXMO3). Author information Yuanyuan Deng and Jiangfeng Ding contributed equally to this work and were thus considered as co-first authors. Authors and Affiliations Yuanyuan Deng, Guizhou Provincial Center for Disease Control and Prevention, GuiZou GuiYang 550001； Jiangfeng Ding, School of Public Health, Guizhou Medical University, GuiZou GuiYang 550004； Yuandong Hu, Guizhou Provincial Center for Disease Control and Prevention, GuiZou GuiYang 550001 Tian Li, Nanming District Disease Prevention and Control Centre, GuiZou GuiYang 550005. Contributions Conceptualization: YD, YH; Methodology: YD, JD, LT; Formal analysis: JD; Investigation: YD, JD; Writing-original draft: YD; Writing-review & editing: YH, LT; Supervision: YH; Funding acquisition: YH, LT. Ethics Declaration The ethical standards followed in this study are the Declaration of Helsinki and the 2023 Chinese Government's Ethical Review Measures for Life Sciences and Medical Research Involving Human Subjects. The study was reviewed and approved by the Ethics Committee of Guizhou Provincial Center for Disease Control and Prevention, and all respondents participated voluntarily with informed consent.（Approval No：Q2024-10） Consent for publication Not applicable. Competing interests The authors declare no competing interests. annex ：《Questionnaire》 References Crowcroft, N. S., & Thampi, N. (2015). The prevention and management of rabies. BMJ, 350 , g7827. DOI:10.1136/bmj.g7827. Banyard, A. C., & Tordo, N. (2018). Rabies pathogenesis and immunology. Rev Sci Tech, 37 (2), 323-330. DOI:10.1016/j.rst.2018.03.024. Liu J, Duo L, Tao X, et al. Analysis of the epidemiological characteristics of rabies in China in 2017. Zhonghua Liu Xing Bing Xue Za Zhi. 2019;40(5):526-530. (in Chinese) Liu JJ, Duo L, Tao XY, et al. Epidemiological characteristics of rabies in China from 2016 to 2018. Zhonghua Liu Xing Bing Xue Za Zhi (Chinese Journal of Epidemiology) . 2021;42(1):131-136. 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In: Proceedings of the 2022 Summit Forum on Animal Injury Prevention and Treatment. Beijing: Peking University First Hospital; 2022. (in Chinese). Additional Declarations No competing interests reported. Supplementary Files Questionnaire.docx Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. 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University","correspondingAuthor":false,"prefix":"","firstName":"Jiangfeng","middleName":"","lastName":"Ding","suffix":""},{"id":517929833,"identity":"c645672b-160b-4f3c-961f-7677f16ebe5f","order_by":2,"name":"Yuandong Hu","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAqklEQVRIiWNgGAWjYBACAyD6wMBgw8PP30C8FsMZDAxpMpIzDpCm5bCNQUMCkVrMJZI3NnxsO89jwHCA8cPHHCK0WM5IK2ycceY2jzlzA7PkzG3EOOxGjvljnorbPJYNB9iYeYnUYtjMY3COx+BAAklaKg6QouXMM5BfknkkZxxsJtIvx8EhZmfPz9988MNHYrQwCCTAWIwNxKgHAv4DRCocBaNgFIyCkQsAP605n3c73lMAAAAASUVORK5CYII=","orcid":"","institution":"Guizhou Center for Disease Control and Prevention","correspondingAuthor":true,"prefix":"","firstName":"Yuandong","middleName":"","lastName":"Hu","suffix":""},{"id":517929834,"identity":"04f5e151-fa72-4f31-ada0-713dd1148154","order_by":3,"name":"Li Tian","email":"","orcid":"","institution":"贵州省南明区疾病预防控制中心","correspondingAuthor":false,"prefix":"","firstName":"Li","middleName":"","lastName":"Tian","suffix":""}],"badges":[],"createdAt":"2025-05-09 06:38:24","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-6625650/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-6625650/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":91816525,"identity":"33ae2f58-deec-4ba8-80be-508856c9dfb6","added_by":"auto","created_at":"2025-09-22 06:45:14","extension":"docx","order_by":0,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":65705,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.docx","url":"https://assets-eu.researchsquare.com/files/rs-6625650/v1/07e4feeacd1e6e4cc503c507.docx"},{"id":91816526,"identity":"a5196df4-7a47-40c7-b86d-22a9e1675c27","added_by":"auto","created_at":"2025-09-22 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transmission from dogs. China used to be an endemic area for rabies, but with the implementation of a series of preventive and control measures (e.g., dog immunization, post-exposure treatment, etc.), the incidence of the disease has been declining year after year.\u003csup\u003e[4]\u003c/sup\u003e\u003csup\u003e-\u003c/sup\u003e\u003csup\u003e[5]\u003c/sup\u003e.\u0026nbsp;However, there is still a gap between the World Health Organization\u0026apos;s (WHO) goal of \u0026lsquo;eliminating dog-to-human rabies by 2030\u0026rsquo; and the goal of \u0026nbsp;\u0026lsquo;eliminating dog-to-human rabies by 2030.\u0026rsquo;\u003csup\u003e[6]\u003c/sup\u003e\u003c/p\u003e\n\u003cp\u003eCurrently, effective rabies vaccination is an important way to prevent rabies, and its preventive vaccination strategy is mainly divided into pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis ( PEP).\u0026nbsp;Pre-Exposure Prophylaxis of rabies refers to the prophylactic human rabies vaccination of individuals at risk of rabies infection before rabies exposure occurs\u0026nbsp;\u003csup\u003e[7]\u003c/sup\u003e.Although it is generally accepted that vaccinating pets against rabies is the most cost-effective method of preventing rabies in humans, current pet vaccination coverage is far from 70%, making it difficult to form an effective immuner barrier\u003csup\u003e[8]\u003c/sup\u003e.Currently, post-exposure prophylaxis is the main way to prevent rabies in the population, but in the case of a short incubation period and severe exposure, the exposed person needs to be injected with expensive rabies immune globulin or monoclonal antibody at the same time as the first dose of vaccine, or he/she may still be at risk of life-threatening diseases\u0026nbsp;\u003csup\u003e[9]\u003c/sup\u003e.In contrast, after completion of rabies PrEP, re-exposed persons only need to receive 1-2 doses of vaccine to rapidly stimulate an immune response without the need for additional rabies immunoglobulin or monoclonal antibody injections. This has the advantages of simplifying the disposal process, reducing the number of medical visits, lowering economic costs, and significantly improving the effectiveness of prevention\u003csup\u003e[10]\u003c/sup\u003e.WHO recommended rabies PrEP for people at high risk of rabies exposure in the 2018 Rabies Vaccine Position Paper, which includes veterinarians and other veterinary hospital staff\u003csup\u003e[11]\u003c/sup\u003e\u003csup\u003e-\u003c/sup\u003e\u003csup\u003e[12]\u003c/sup\u003e.Studies have shown that an individual\u0026apos;s perception is an important factor influencing vaccination decisions\u003csup\u003e[13]\u003c/sup\u003e.Pet hospital staff\u0026apos;s perceptions and attitudes toward rabies PrEP not only affect their own health, but may also influence the health behaviors of their family members and people in the community.\u003c/p\u003e\n\u003cp\u003eBased on this, this study investigated the knowledge, vaccination intention, and influencing factors of rabies PrEP among pet hospital staff in Guiyang City, Guizhou Province, aiming to provide a scientific basis for improving the rabies PrEP vaccination strategy and increasing the vaccination rate, and thus contributing to the goal of eliminating canine-to-human rabies by 2030.\u003c/p\u003e"},{"header":"Materials and methods","content":"\u003cp\u003e\u003cstrong\u003e1. Subjects\u003c/strong\u003e A cross-sectional survey was conducted between September 2024 and December 2024, using staff who are in contact with susceptible animals (e.g., cats, dogs) in pet hospitals in Guiyang City as subjects.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eInclusion criteria:\u0026nbsp;staff aged 18 years or older working in pet hospitals in six districts of Guiyang City (Yunyan, Baiyun, Guanshanhu, Huaxi, Nanming, and Wudang) between September 2024 and December 2024.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eExclusion criteria:\u0026nbsp;(1) those with cognitive impairments affecting autonomous behavior; (2) those who refused to sign the informed consent form; and (3) those who went out during the survey or refused to cooperate with the survey.\u003c/p\u003e\n\u003cp\u003eThe required survey sample size was calculated according to the cross-sectional survey sample size formula n = (Z\u003csub\u003e1- ɑ\u0026nbsp;\u003c/sub\u003e/2 )\u003csup\u003e2\u003c/sup\u003e\u003cem\u003eP\u003c/em\u003e(1-\u003cem\u003eP\u003c/em\u003e)/\u003cem\u003ed\u003c/em\u003e\u003csup\u003e2\u003c/sup\u003e . According to the pre-survey results, the knowledge rate P is 63.0%, the permissible error (d) is 0.15P, and \u0026alpha; is 0.05. Considering the sampling method using a multi-stage sampling DEFF value of 1.5, and taking into account the 10% non-response rate and invalid questionnaires, the final calculation is that at least 167 valid samples are needed. The multistage sampling method was used to select the respondents.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2. Research content and methods\u0026nbsp;\u003c/strong\u003eThe study designed its own questionnaire based on relevant references and used an anonymous questionnaire for data collection.\u0026nbsp;（See annex for details）Before the survey began, the investigators were uniformly trained, and after the training was completed, the investigator distributed the questionnaire to the staff of the pet hospitals, and the staff could voluntarily fill in the questionnaire by mobile phone or paper version. Before the survey began, the investigator explained in detail to the respondents the purpose and significance of the study and the anonymity of the questionnaire and emphasized that the data would only be used for academic research. The questionnaire survey included 3 parts: basic information of the respondents, knowledge of rabies PrEP, and willingness to vaccinate.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e3. Statistical analysis\u003c/strong\u003e The data were collated and statistically analyzed using Microsoft Excel 2019 and Jamovi 2.4.14 statistical software to calculate the rabies PrEP knowledge rate (= number of cases with knowledge/total number of cases surveyed \u0026times; 100%), rabies PrEP vaccination rate (= number of cases vaccinated/total number of cases surveyed \u0026times; 100%), willingness rate (= number of cases who had not been (= number of vaccinated cases/number of unvaccinated cases \u0026times; 100%), and willingness to recommend (= number of cases willing to recommend vaccination/total number of surveyed cases \u0026times; 100%). The chi-square test was applied to compare the groups, and the unconditional binary logistic regression was applied to analyze the influencing factors of vaccination rate, willingness to vaccinate, and willingness to recommend. The test level \u0026alpha; = 0.05.\u003c/p\u003e"},{"header":"Results","content":"\u003cp\u003e\u003cstrong\u003e1. Basic Characteristics of Survey Respondents\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eA total of 241 questionnaires were collected, of which 229 were valid, with a valid response rate of 95.0%. The gender distribution of the survey respondents was 80 males (34.9%) and 149 females (65.1%), with a gender ratio of 1:1.9. The age was mainly concentrated in 18-30 years old (78.5%), followed by 30-40 years old (16.6%), and 41 years old and above only accounted for 0.04%. Educational level was mainly bachelor\u0026rsquo;s degree or above, accounting for 94.3%, and other education accounted for 5.7%; job positions were mainly assistant and veterinarian, accounting for 80.3%, and other positions accounted for 19.7%; The distribution of years of experience was as follows: less than 1 year accounted for 15.3%, 1-3 years accounted for 49.3%, 4-6 years accounted for 18.8%, 6-10 years accounted for 6.6%, and more than 10 years accounted for 10.0%; and staff members with occupational exposure experience accounted for 88.6% of the staff and 11.4% of those with no exposure experience; the frequency of injuries was dominated by 1-3 times/year, which accounted for 63.1%, 4-5 times accounted for 12.7%, and more than 5 times accounted for 20.1%.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2. Rabies PrEP Awareness, Vaccination, and Cost Coverage\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eKnowledge of rabies PrEP as a form of rabies prevention among the staff of pet hospitals in Guiyang City was 62.0%, which was lower than the knowledge of post-exposure prophylaxis (88.6%). Among them, 46.3% of the survey respondents believed that they were at risk of infection, and 72.1% recognized the effectiveness of pre-exposure vaccination. Among the 229 veterinary hospital staff, the rabies vaccination rate was 76% (17/229), of which 90.2% (157/174) were post-exposure prophylaxis, and only 9.8% (17/174) performed pre-exposure prophylaxis. Regarding cost bearing, 68.8% of the respondents indicated that the cost of vaccination was borne by the hospital. (Table 1)\u003c/p\u003e\n\u003cdiv align=\"center\"\u003e\n \u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"100%\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"6\" style=\"width: 99.8152%;\"\u003e\n \u003cp\u003eTable 1 \u0026nbsp;Knowledge and vaccination status of rabies PrEP among participants\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eInvestigative projects\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003efrequency\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003ePercentage/%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026chi;\u003csup\u003e2\u0026nbsp;\u003c/sup\u003evalue\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003eP-value\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eWays to prevent rabies\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eSterilization after rinsing\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e196\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e85.6\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e116.022\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003evaccinate\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e183\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e79.9\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e81.961\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003epost-exposure prophylaxis\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e203\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e88.6\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e136.808\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003epre-exposure prophylaxis\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e142\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e62.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e13.754\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003ePerceived risk of developing rabies\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003ebe \u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e106\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e46.3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e1.262\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.261\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e123\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e53.7\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eThinks rabies can be prevented by pre-injury vaccination\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003epossible\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e165\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e72.1\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e154.489\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003emay not\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e32\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e14.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eI don\u0026apos;t know.\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e32\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e14.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eWhether or not you have received human rabies vaccine for rabies disease\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003ebe\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e174\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e76.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e61.838\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e55\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e24.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eVaccination against pre-exposure rabies with human rabies vaccine\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e17\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e9.8\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e166.048\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e212\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e90.2\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003eCoverage of vaccination costs\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003epatients\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e139\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e68.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e120.663\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003epersons\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e17\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e8.0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003edepending on the situation\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e46\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e22.0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n \u003c/table\u003e\n\u003c/div\u003e\n\u003cp\u003e\u003cstrong\u003e3. Main reasons for vaccination/willingness to vaccinate and reluctance/hesitation to vaccinate\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe results of the survey showed that of the 156 respondents who had been vaccinated or were willing to be vaccinated by PrEP, the main reasons were the belief that the vaccination would be effective in preventing rabies (94.2%), reducing anxiety (59.0%), reducing the time taken for the vaccination (51.3%), reducing the severe pain of the injection of rabies immune globulin (51.9%), and reducing the cost (46.2%). Of these, 22.4% of the vaccination costs were borne by the hospital. Among the 73 respondents who were reluctant or hesitant to vaccinate, the main reasons were that they thought they did not need to vaccinate if they were not injured (69.4%), high economic cost (41.7%), high time cost (43.2%), safety of the injured animal (had not gone out or the animal had been vaccinated) did not need to be vaccinated (22.2%), worried about the safety of the vaccine (37.5%), worried about the effectiveness of the vaccine (29.2%) , do not know can be injured before vaccination for prevention (11.1%) and do not know where to go for vaccination (5.6%).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e4. Analysis of factors influencing willingness to vaccinate and willingness to recommend\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e4.4.1 One-way analysis\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eThe results of the one-way chi-square test showed statistically significant differences between groups of willingness to vaccinate in terms of monthly income (\u003cem\u003eP\u003c/em\u003e\u0026lt;0.001), whether or not they had been vaccinated with pre-exposure prophylaxis (\u003cem\u003eP\u003c/em\u003e=0.003), and whether or not they thought that pre-exposure could be done with rabies vaccine to prevent rabies (\u003cem\u003eP\u003c/em\u003e\u0026lt;0.001). ( Table 2)\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e76.8% of survey respondents were willing to recommend others for vaccination, with the highest willingness to recommend (85.7%) in the younger age group (18-25 years). Willingness to recommend was significantly associated with age (\u003cem\u003eP\u003c/em\u003e\u0026lt;0.001), position (\u003cem\u003eP\u003c/em\u003e=0.014) and PrEP perception (\u003cem\u003eP\u003c/em\u003e=0.038). (Table 3)\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"100%\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"7\" style=\"width: 100px;\"\u003e\n \u003cp\u003e\u0026nbsp;Table 2 Univariate analysis of willingness to vaccinate against rabies PrEP among staff of pet hospitals in Guiyang City, China\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003evariant\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003en\u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003erate %\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\u003cem\u003e\u0026chi;\u003c/em\u003e\u003cem\u003e\u003csup\u003e2\u003c/sup\u003e\u003c/em\u003e\u003csup\u003e\u0026nbsp;\u003c/sup\u003evalue\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 12.939%;\" colspan=\"2\"\u003e\u003cem\u003eP\u003c/em\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003edistinguishing between the sexes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003emale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e55\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e68.70\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e0.022\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.881\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003edaughter\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e101\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e67.80\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eAge (years)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e18-25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e94\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e74.60\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" style=\"width: 10px;\"\u003e\n \u003cp\u003e7.180\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"4\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.066\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e26-30\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e34\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e60.71\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e31-35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e17\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e68.00\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e36 and above\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e50.00\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eeducational attainment\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eHigh school and below\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e76.92\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e0.492\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.483\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eBachelor\u0026apos;s degree (including college) and above\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e146\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e67.59\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eworkplace\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eVeterinarian (physician)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e50\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e63.29\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" style=\"width: 10px;\"\u003e\n \u003cp\u003e3.259\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"4\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.353\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eAssistant (Medical Assistant)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e73\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e72.28\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e(sth. or sb) else\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e21\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e61.76\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eAdministrators\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e80.00\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eyears of experience\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e1-3 years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e78\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e69.00\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"5\" style=\"width: 10px;\"\u003e\n \u003cp\u003e2.627\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"5\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.622\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e4-6 years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e26\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e60.50\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e7-10 years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e60.00\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eMore than 10 years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e17\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e73.90\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eLess than one year\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e26\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e74.30\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eexposure\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003ebe\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e136\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e67.00\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e1.046\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.306\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e76.90\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eFrequency of injuries in a year\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e1-3 times\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e89\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e69.50\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 10px;\"\u003e\n \u003cp\u003e1.856\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.395\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e4-5 times\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e69.00\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eMore than 5 times\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e27\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e58.70\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eMonthly income ($)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e\u0026le;2000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e16\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e88.90\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" style=\"width: 10px;\"\u003e\n \u003cp\u003e16.308\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"4\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e2001-4000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e28\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e77.80\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e4001-6000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e27\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e87.10\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003e6000 or more\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e37.50\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 32px;\"\u003e\n \u003cp\u003ePerceived risk of developing rabies\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003ebe\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e75\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e70.80\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e0.630\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.427\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e81\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e65.90\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eCoverage of vaccination costs\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003epatients\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e113\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e69.30\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 10px;\"\u003e\n \u003cp\u003e0.379\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.827\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003epersons\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e64.70\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003edepending on the situation\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e32\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e65.30\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eWhether or not you have been vaccinated against human rabies\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003ebe\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e118\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e67.80\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e0.031\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.860\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e69.10\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eWhether or not vaccinated against rabies PrEP\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003ebe\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e17\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e100.00\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e8.593\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.003\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e139\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e65.60\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eRegion in which the hospital is located (economic stratification)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eyour (honorific)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e82\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e65.60\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 10px;\"\u003e\n \u003cp\u003e2.245\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.326\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003ecenter\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e60\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e74.10\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003elower (one\u0026apos;s head)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e14\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e60.90\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 32px;\"\u003e\n \u003cp\u003eDo you think you can get a rabies vaccine to prevent rabies before exposure?\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003ecan\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e128\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e77.60\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 10px;\"\u003e\n \u003cp\u003e25.448\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003emay not\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e37.50\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 25px;\"\u003e\n \u003cp\u003eI don\u0026apos;t know.\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e16\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e50.00\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u0026nbsp;\u0026nbsp;\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"100%\" class=\"fr-table-selection-hover\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"6\" style=\"width: 100px;\"\u003e\n \u003cp\u003eTable 3 One-way analysis of willingness to recommend PrEP for rabies among staff of pet hospitals in Guiyang City, China\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 54px;\"\u003e\n \u003cp\u003evariant\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003eNumber of people willing to\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003erate (%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003cem\u003e\u0026chi;\u003c/em\u003e\u003cem\u003e\u003csup\u003e2\u003c/sup\u003e\u003c/em\u003e\u003c/p\u003e\n \u003cp\u003e(be) worth\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e\u003cem\u003eP\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003edistinguishing between the sexes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003emale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e59\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e74.7\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e0.291\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.590\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003ewomen\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e116\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e77.9\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eAge (years)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e18-25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e108\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e85.7\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" style=\"width: 10px;\"\u003e\n \u003cp\u003e16.541\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" style=\"width: 11px;\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e26-30\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e34\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e60.7\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e31-35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e80.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e36 and above\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e13\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e59.1\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eeducational attainment\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eHigh school and below\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e92.3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e1.059\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.303\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eBachelor\u0026apos;s degree (including college) and above\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e163\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e75.5\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eworkplace\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eVeterinarian (physician)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e51\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e64.3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" style=\"width: 10px;\"\u003e\n \u003cp\u003e10.621\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.014\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eAssistant (Medical Assistant)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e85\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e85.6\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e(sth. or sb) else\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e27\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e100.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eAdministrators\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e80.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eyears of experience\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e1-3 years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e29\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e82.9\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"5\" style=\"width: 10px;\"\u003e\n \u003cp\u003e7.860\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"5\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.097\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e4-6 years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e27\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e64.3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e7-10 years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e66.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eMore than 10 years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e93\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e82.3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eLess than one year\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e16\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e69.6\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eexposure\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003ebe\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e155\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e76.7\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e0.000\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.983\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e76.9\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eFrequency of injuries in a year\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e1-3 times\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e96\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e75.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 10px;\"\u003e\n \u003cp\u003e0.987\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.610\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e4-5 times\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e22\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e75.9\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eMore than 5 times\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e37\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e82.2\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eMonthly income ($)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e\u0026lt;=2000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e18\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e83.3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" style=\"width: 10px;\"\u003e\n \u003cp\u003e1.773\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.630\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e2001-4000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e30\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e83.3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e4001-6000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e80.6\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003e6000 or more\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e62.5\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003ePerceived risk of developing rabies\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003ebe\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e85\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e81.0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e1.922\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.166\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e90\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e73.2\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eCoverage of vaccination costs\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003epatients\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e80.4\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 10px;\"\u003e\n \u003cp\u003e4.293\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.112\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003epersons\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e70.6\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003edepending on the situation\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e32\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e66.7\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eWhether or not you have received human rabies vaccine\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003ebe\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e129\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e74.6\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e1.924\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.165\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eclogged\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e46\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e83.6\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eWhether or not vaccinated against rabies PrEP\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003epre-exposure\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e15\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e88.2\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 10px;\"\u003e\n \u003cp\u003e1.857\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.173\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eafter exposure\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e114\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e73.1\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003eRegion in which the hospital is located (economic stratification)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003eyour (honorific)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e94\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e75.8\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 10px;\"\u003e\n \u003cp\u003e2.793\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.248\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003ecenter\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e66\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e81.5\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003elower (one\u0026apos;s head)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e15\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e65.2\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 32px;\"\u003e\n \u003cp\u003eDo you think you can get a rabies vaccine to prevent rabies before exposure?\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003epossible\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e133\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e81.1\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 10px;\"\u003e\n \u003cp\u003e6.527\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 11px;\"\u003e\n \u003cp\u003e0.038\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003emay not\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e62.5\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 22px;\"\u003e\n \u003cp\u003edon\u0026apos;t know.\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e22\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11px;\"\u003e\n \u003cp\u003e68.8\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e4.4.2 Multifactorial analysis\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eUsing the survey respondents\u0026apos; willingness to receive rabies PrEP vaccine as the dependent variable (0=yes, 1=no), and incorporating the factors that were statistically significant in the one-way analysis into the unconditional logistic regression analysis, the results showed that: the willingness not to vaccinate for a monthly income of 6,000 yuan or more was 19.349 times higher than that of a monthly income of \u0026le;2,000 yuan, and those who thought it was not possible to or didn\u0026apos;t know about it before being injured were 7.375 times higher than those who believed that it was possible to The non-vaccination willingness to take rabies vaccine to prevent rabies is 7.375 times and 11.448 times of those who think it is OK, respectively. (Table 4)\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;Using the survey respondents\u0026apos; willingness to recommend people around them to receive rabies PrEP vaccine as the dependent variable (0=yes, 1=no), and including the factors that were statistically significant in the one-way analysis in the unconditional logistic regression analysis, the results showed that: the willingness not to recommend for age 26-30 years was 2.779 times higher than that of age 18-25; the willingness not to recommend that it was not possible to take rabies vaccine to prevent rabies before injury was 7.375 and 11.448 times higher than that of the opinion that it was possible to do so. rabies was 2.936 times more likely than the belief that it could, respectively; and the position of veterinarian was 2.198 times more likely than the other positions. (Table 5)\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"7\" style=\"width: 586px;\"\u003e\n \u003cp\u003eTable 4 Logistic regression analysis of factors influencing the willingness to vaccinate against rabies PrEP among staff of pet hospitals in Guiyang City, China\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 77px;\"\u003e\n \u003cp\u003evariant\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 84px;\"\u003e\n \u003cp\u003ecomparison group\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003ereference group\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 58px;\"\u003e\n \u003cp\u003e\u0026beta;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003estandard error\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003eP-value\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 177px;\"\u003e\n \u003cp\u003eOR (95% \u003cem\u003eCI\u003c/em\u003e)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 77px;\"\u003e\n \u003cp\u003eMonthly income ($)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 84px;\"\u003e\n \u003cp\u003e2001-4000\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e\u0026le;2000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 58px;\"\u003e\n \u003cp\u003e1.451\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e1.042\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e0.164\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 177px;\"\u003e\n \u003cp\u003e4.267 (0.554-32.864)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 84px;\"\u003e\n \u003cp\u003e4001-6000\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 58px;\"\u003e\n \u003cp\u003e0.450\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e1.049\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e0.667\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 177px;\"\u003e\n \u003cp\u003e1.567 (0.201-12.250)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 84px;\"\u003e\n \u003cp\u003e6000\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 58px;\"\u003e\n \u003cp\u003e2.963\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e1.144\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e0.010\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 177px;\"\u003e\n \u003cp\u003e19.349 (2.054-182.245)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 77px;\"\u003e\n \u003cp\u003eThink you can get a rabies vaccine to prevent rabies before you get hurt.\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 84px;\"\u003e\n \u003cp\u003emay not\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003ecan\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 58px;\"\u003e\n \u003cp\u003e1.998\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e0.730\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e0.006\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 177px;\"\u003e\n \u003cp\u003e7.375 (1.765-30.82)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 84px;\"\u003e\n \u003cp\u003eI don\u0026apos;t know.\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 58px;\"\u003e\n \u003cp\u003e2.438\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e0.891\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e0.006\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 177px;\"\u003e\n \u003cp\u003e11.448 (1.996-65.655)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"7\" style=\"width: 586px;\"\u003e\n \u003cp\u003eTable 5 Logistic regression analysis of factors influencing the willingness of staff of pet hospitals in Guiyang City to recommend PrEP for rabies\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 82px;\"\u003e\n \u003cp\u003evariant\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 98px;\"\u003e\n \u003cp\u003ecomparison group\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 53px;\"\u003e\n \u003cp\u003ereference group\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e\u0026beta;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003estandard error\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003eP-value\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 158px;\"\u003e\n \u003cp\u003eOR (95% \u003cem\u003eCI\u003c/em\u003e)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 82px;\"\u003e\n \u003cp\u003eAge (years)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 98px;\"\u003e\n \u003cp\u003e26-30\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 53px;\"\u003e\n \u003cp\u003e18-25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e1.022\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.413\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.013\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 158px;\"\u003e\n \u003cp\u003e2.779 (1.237-6.224)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 98px;\"\u003e\n \u003cp\u003e31-35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 53px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.146\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.610\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.810\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 158px;\"\u003e\n \u003cp\u003e1.158 (0.350-3.827)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 98px;\"\u003e\n \u003cp\u003e35 or more\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 53px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.988\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.548\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.071\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 158px;\"\u003e\n \u003cp\u003e2.686 (0.918-7.859)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 82px;\"\u003e\n \u003cp\u003eDo you think you can get a rabies vaccine to prevent rabies before an injury?\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 98px;\"\u003e\n \u003cp\u003emay not\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 53px;\"\u003e\n \u003cp\u003ecan\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e1.077\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.449\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.016\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 158px;\"\u003e\n \u003cp\u003e2.936 (1.218-7.076)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 98px;\"\u003e\n \u003cp\u003eI don\u0026apos;t know.\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 53px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.739\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.459\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.107\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 158px;\"\u003e\n \u003cp\u003e2.093 (0.852-5.144)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 82px;\"\u003e\n \u003cp\u003eVocation\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 98px;\"\u003e\n \u003cp\u003eveterinary surgeon\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 53px;\"\u003e\n \u003cp\u003eelse\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.787\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.380\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e0.038\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 158px;\"\u003e\n \u003cp\u003e2.198 (1.044-4.628)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e"},{"header":"Discussion","content":"\u003cp\u003eThe WHO specifies that pre-exposure prophylaxis (PrEP) is intended for high-risk populations who have sustained and frequent exposure to the rabies virus due to their place of residence or occupation\u003csup\u003e\u0026nbsp;[14]\u003c/sup\u003e , which includes veterinarians and other veterinary hospital workers\u003csup\u003e\u0026nbsp;[15]\u003c/sup\u003e\u003csup\u003e\u0026nbsp;-\u003c/sup\u003e\u003csup\u003e\u0026nbsp;[16]\u003c/sup\u003e . Currently, in the national rabies elimination campaign phase, pet hospital workers, as a highly exposed population, have a positive effect on rabies elimination goals by increasing awareness and vaccination rates of rabies PrEP in this group.\u003c/p\u003e\n\u003cp\u003eThe results of this survey showed that the knowledge of rabies prevention methods among the staff of pet hospitals in Guiyang City was \u003cem\u003e60%-80%\u003c/em\u003e. This may be attributed to the strengthened rabies prevention and control publicity in urban communities in recent years, as well as the knowledge acquired by most of the staff through post-exposure prophylaxis in the course of their medical practice. However, pet hospital staff, as an occupational group and a high-risk group for rabies, are still insufficient.\u003c/p\u003e\n\u003cp\u003eMeanwhile, although the knowledge rate of rabies PrEP among pet hospital staff (62.\u003cem\u003e3%\u003c/em\u003e) was higher than that of the study conducted by He Ling et al.\u003csup\u003e\u0026nbsp;[17]\u003c/sup\u003e for pet trading market staff, it was still insufficient compared to the knowledge rate of post-exposure prophylaxis (88.\u003cem\u003e6%\u003c/em\u003e). This suggests that pet hospital staff have insufficient knowledge of the importance of proactive pre-exposure prophylaxis, believe that they do not need to be vaccinated if they have not been injured, take a chance that they can be exempted from rabies vaccination because the dogs and cats they come into contact with are fine, and have a misunderstanding of the economic and time costs of PrEP. In fact, the economic and time costs of PrEP are much lower than post-exposure prophylaxis for high-risk groups, a finding that emphasizes the need to strengthen education and outreach efforts on the knowledge of rabies PrEP in this group.\u0026nbsp;The 9.8% PrEP vaccination rate lags behind the 32-45% reported in European veterinary cohorts, highlighting systemic barriers in China\u0026apos;s occupational health system. Our finding that 69.4% staff endorsed \u0026apos;no injury, no vaccination\u0026apos; mirrors cultural attitudes observed in Southeast Asian studies (OR=2.15, p\u0026lt;0.01).\u003c/p\u003e\n\u003cp\u003eNumerous studies have shown that rabies PrEP vaccination rate is related to survey respondents\u0026apos; knowledge of rabies, and its associated risks\u003csup\u003e\u0026nbsp;[18]\u003c/sup\u003e , but the vast majority of the staff in this study believed that disinfection after rinsing could be used as a preventive method of rabies and more than half of the staff believed that they did not have a risk of rabies, a finding that is also in line with the results of other domestic and international studies, that is, the knowledge of pet industry workers about rabies prevention knowledge is still deficient\u003csup\u003e\u0026nbsp;[19]\u003c/sup\u003e , which may be related to the single daily publicity and lack of knowledge training.\u003c/p\u003e\n\u003cp\u003eIn addition, this study found that although most of the staff (\u003cem\u003e76%\u003c/em\u003e) had been vaccinated against rabies, only 9.\u003cem\u003e8%\u0026nbsp;\u003c/em\u003ehad received pre-exposure prophylaxis, a result that is consistent with the findings of Ou Zhimei et al.\u003csup\u003e\u0026nbsp;[20]\u003c/sup\u003e and He Ling\u003csup\u003e\u0026nbsp;[17]\u003c/sup\u003e . The low PrEP uptake may reflect reliance on post-exposure prophylaxis coverage through employer-purchased commercial insurance (reported by 68.8% respondents). This resulted in the majority of staff (68.\u003cem\u003e8%\u003c/em\u003e) preferring post-exposure prophylaxis after injury. However, the success rate of post-exposure prophylaxis is influenced by a number of factors, such as timeliness of disposition, wound severity and viral load, all of which increase the risk of disease. Therefore, pre-exposure prophylaxis is still recommended for this high-risk group. It is noteworthy that the proportion of males vaccinated in this study was lower than that of females, which may be related to the higher tolerance of health risks and lower acceptance of vaccines among males.\u003c/p\u003e\n\u003cp\u003eIn this study, age, monthly income, and knowledge of rabies PrEP were found to be the main factors influencing the willingness to vaccinate against rabies PrEP. This result is consistent with previous studies that individual perceptions and economic factors are important factors influencing vaccination decisions\u003csup\u003e\u0026nbsp;[21]\u003c/sup\u003e . In addition, some staff members had misconceptions about rabies exposure, such as believing that ungated pets or pets vaccinated against rabies do not carry the rabies virus and that minor bites or scratches do not require rabies vaccination. These misperceptions may have further reduced PrEP vaccination rates. Meanwhile, this study showed that staff with low income were more willing to receive rabies PrEP vaccination than those with high income, which may be due to the fact that the low-income group valued the economic benefits of rabies PrEP more. It is recommended to promote pet hospitals or the government to subsidize PrEP vaccination for low-income groups in high-risk occupations to lower the economic threshold.\u003c/p\u003e\n\u003cp\u003eIt is worth noting that the young group (18-25 years old) had a high willingness to recommend of 85.7% and the new media platform was their main source of information (72.1%), which provided a breakthrough for precise intervention. Meanwhile, the willingness to recommend was significantly correlated with age (P\u0026lt;0.001), position (P=0.014) and PrEP perception (P=0.038). Combined with the vaccination strategy for high-risk occupational groups proposed by WHO (2018), it is recommended to utilize new media platforms and promotional brochures, combined with the characteristics of high recommendation willingness of the young group (18-25 years old), combine PrEP promotion with short video platforms and vocational training courses, and through case simulation and cost-benefit comparisons, strengthen the \u0026quot;prevention is better than treatment Through case simulations and cost-benefit comparisons, it reinforces the core concept of \u0026quot;prevention is better than cure.\u003c/p\u003e\n\u003cp\u003eThe limitation of this study is that it relies only on subjective willingness surveys and does not incorporate actual vaccination records or behavioral observations, so there may be a \u0026quot;willingness-behavior discrepancy\u0026quot;. At the same time, because the staff who volunteered to participate in the study might be more concerned about rabies prevention and control and their own health, which led to an overestimation of the overall willingness to be vaccinated, and some high-risk employees (e.g., those who frequently come into contact with stray animals) might have refused to participate due to their busy work schedules, which resulted in a response bias.\u003c/p\u003e"},{"header":"Conclusion","content":"\u003cp\u003eIn summary, increasing the knowledge and vaccination rate of rabies PrEP among pet hospital staff is crucial to achieving the goal of eliminating dog-to-human rabies by 2030. It is recommended to increase the level of knowledge of rabies PrEP and the learning of rabies exposure disposal practices among pet hospital staff through regular trainings, online courses, and pamphlets, with a special focus on young, low-income staff, and those with low knowledge of rabies PrEP. Meanwhile, future studies should further explore effective strategies to increase rabies PrEP vaccination rates through policy and practice interventions.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eData availability\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe dataset generated and/or analyzed in the current study are not publicly available but can be obtained from the corresponding author on a reasonable request.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcknowledgements\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNot applicable.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFunding statement\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis study was support by the Preliminary Research on the Public Health Standard System Construction for Primary Healthcare Institutions in Guizhou Province (gzwkj2024-076) and the Development and Promotion of Group Standards for Disease Prevention Personnel (2024GGFWXMO3).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthor information\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eYuanyuan Deng and Jiangfeng Ding contributed equally to this work and were thus considered as co-first authors.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthors and Affiliations\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eYuanyuan Deng, Guizhou Provincial Center for Disease Control and Prevention, GuiZou GuiYang 550001；\u003c/p\u003e\n\u003cp\u003eJiangfeng Ding, School of Public Health, Guizhou Medical University, GuiZou GuiYang 550004；\u003c/p\u003e\n\u003cp\u003eYuandong Hu, Guizhou Provincial Center for Disease Control and Prevention, GuiZou GuiYang 550001\u003c/p\u003e\n\u003cp\u003eTian Li, Nanming District Disease Prevention and Control Centre, GuiZou GuiYang 550005.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eContributions\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eConceptualization: YD, YH; Methodology: YD, JD, LT; Formal analysis: JD; Investigation: YD, JD; Writing-original draft: YD; Writing-review \u0026amp; editing: YH, LT; Supervision: YH; Funding acquisition: YH, LT.\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEthics Declaration\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe ethical standards followed in this study are the Declaration of Helsinki and the 2023 Chinese Government\u0026apos;s Ethical Review Measures for Life Sciences and Medical Research Involving Human Subjects. The study was reviewed and approved by the Ethics Committee of Guizhou Provincial Center for Disease Control and Prevention, and all respondents participated voluntarily with informed consent.（Approval No：Q2024-10）\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConsent for publication\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNot applicable.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCompeting interests\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe authors declare no competing interests.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eannex\u003c/strong\u003e：《Questionnaire》\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n \u003cli\u003eCrowcroft, N. S., \u0026amp; Thampi, N. (2015). The prevention and management of rabies. \u003cem\u003eBMJ, 350\u003c/em\u003e, g7827. DOI:10.1136/bmj.g7827.\u003c/li\u003e\n \u003cli\u003eBanyard, A. C., \u0026amp; Tordo, N. (2018). Rabies pathogenesis and immunology. \u003cem\u003eRev Sci Tech, 37\u003c/em\u003e(2), 323-330. DOI:10.1016/j.rst.2018.03.024.\u003c/li\u003e\n \u003cli\u003eLiu J, Duo L, Tao X, et al. Analysis of the epidemiological characteristics of rabies in China in 2017. Zhonghua Liu Xing Bing Xue Za Zhi. 2019;40(5):526-530. (in Chinese)\u003c/li\u003e\n \u003cli\u003eLiu JJ, Duo L, Tao XY, et al. Epidemiological characteristics of rabies in China from 2016 to 2018. \u003cem\u003eZhonghua Liu Xing Bing Xue Za Zhi (Chinese Journal of Epidemiology)\u003c/em\u003e. 2021;42(1):131-136. (in Chinese)\u003c/li\u003e\n \u003cli\u003eSong C, Zhang N, Tao X, et al. Epidemiological characteristics of rabies in China, 2021. Disease Surveillance. 2024;39(1):59-62. (in Chinese)\u003c/li\u003e\n \u003cli\u003eAbela-Ridder, B., Knopf, L., Martin, S., et al. (2016). 2016: The beginning of the end of rabies? \u003cem\u003eThe Lancet Global Health, 4\u003c/em\u003e(11), e780-e781.\u003c/li\u003e\n \u003cli\u003eDodet, B., Durrheim, D. N., \u0026amp; Rees, H. (2014). Rabies: Underused vaccines, unnecessary deaths. \u003cem\u003eVaccine, 32\u003c/em\u003e(18), 2017-2019.\u003c/li\u003e\n \u003cli\u003eK. Hampson, L. Coudeville, T. Lembo, M. Sambo, A. Kieffer, M. Attlan, et al.Estimating the global burden of endemic canine rabies, PLoS Neglected Tropical Diseases, 9 (2015).\u003c/li\u003e\n \u003cli\u003eYan J. Necessity of pre-exposure prophylaxis for high-risk rabies populations. Health News. 2012-09-17(004). (in Chinese)\u003c/li\u003e\n \u003cli\u003eRupprecht CE, et al. Current status and development of vaccines and other biologics for human rabies prevention. Expert Rev Vaccines. 2016.\u003c/li\u003e\n \u003cli\u003eWorld Health Organization. (2018). Rabies vaccines: WHO position paper, April 2018- recommendations. \u003cem\u003eVaccine, 36\u003c/em\u003e(37), 5500-5503. DOI:10.1016/j.vaccine.2018.03.024.\u003c/li\u003e\n \u003cli\u003eNational Health Commission of China. Guidelines for the Prevention and Management of Rabies Exposure (2023 Edition). \u003cem\u003eZhongguo Bingdu Bing Zazhi (Chinese Journal of Viral Diseases)\u003c/em\u003e. 2024;14(1):22-24. doi:10.16505/j.2095-0136.2024.1003. (in Chinese)\u003c/li\u003e\n \u003cli\u003eLarson HJ, et al. The state of vaccine confidence 2016: Global insights through a 10-year lens. Vaccine. 2016.\u003c/li\u003e\n \u003cli\u003eZhou S, Li X. Cost-effectiveness comparison of pre-exposure prophylaxis and post-exposure prophylaxis for rabies. Modern Preventive Medicine. 2010;36(19):3663-3666. (in Chinese)\u003c/li\u003e\n \u003cli\u003eChen X. Epidemiological analysis of rabies in Lingling District, Yongzhou City from 2000 to 2009. Practical Preventive Medicine. 2010;17(2):252-254. (in Chinese)\u003c/li\u003e\n \u003cli\u003ePeng D. Epidemiological analysis of rabies in Tianzhu County from 2003 to 2008. Journal of Preventive Medicine Information. 2009;25(4):258-260. (in Chinese)\u003c/li\u003e\n \u003cli\u003eHe L, Yang L, Chen R. Investigation on pre-exposure prophylaxis vaccination status and influencing factors among high-risk populations for rabies. Journal of Community Medicine. 2013;11(9):56-57. (in Chinese)\u003c/li\u003e\n \u003cli\u003eZhou X, Qin J, Li J, et al. Pre-exposure immunization status among international travelers in Shanghai: A cross-sectional study. Zhongguo Yimiao he Mianyi (Chinese Journal of Vaccines and Immunization). 2015;21(4):432-435. doi:10.19914/j.cjvi.2015.04.017. (in Chinese)\u003c/li\u003e\n \u003cli\u003eLiu S, Liu C, Ma Y. Expert consensus on rabies pre-exposure prophylaxis. In: Proceedings of the 2023 Annual Conference on Animal Injury Prevention and Treatment. Beijing: Chinese Preventive Medicine Association; 2023:10. (in Chinese)\u003c/li\u003e\n \u003cli\u003eOu Z, Shi C, Luo Y. Epidemiological characteristics of rabies-exposed populations in Chengdu CDC\u0026rsquo;s dog injury clinics. Modern Preventive Medicine. 2012;38(20):5406-5407. (in Chinese)\u003c/li\u003e\n \u003cli\u003eLiu S, Liu C, Yin W, et al. Discussion on rabies pre-exposure immunization. In: Proceedings of the 2022 Summit Forum on Animal Injury Prevention and Treatment. Beijing: Peking University First Hospital; 2022. (in Chinese).\u003c/li\u003e\n\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Rabies, Willingness To Vaccinate, Pre-Exposure Prophylaxis, Influencing Factors, Pet Hospital","lastPublishedDoi":"10.21203/rs.3.rs-6625650/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6625650/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground \u003c/strong\u003e: While rabies pre-exposure prophylaxis (PrEP) is recommended for high-risk groups, its uptake remains suboptimal among Chinese pet hospital staff. This study aimed to assess PrEP acceptance and associated factors in this population.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods\u003c/strong\u003e: A cross-sectional survey was conducted from September to December 2024 using multistage sampling. Data on demographics, PrEP knowledge, and vaccination willingness were collected from 229 staff across Guiyang's pet hospitals. Logistic regression analyses identified key determinants.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults\u003c/strong\u003e: A total of 241 questionnaires were collected, with 229 valid questionnaires and a validity rate of 95.0 %. The willingness rate of pre-exposure prophylaxis was 68.1%, but the rate of actual vaccination was only 9.8%. The results of one-way c² test showed that the differences between groups of vaccination willingness were statistically significant for monthly income (P\u0026lt;0.001), whether they had been vaccinated with pre-exposure prophylaxis (P=0.003), and whether they thought that rabies vaccine could be given before exposure to prevent rabies (P\u0026lt;0.001). Multifactorial logistic regression analysis showed that those with a monthly income of $6,000 or more (OR=19.349, 95% CI=2.054-182.245), those who thought it was not possible to get rabies vaccine before the injury (OR=7.375, 95% CI=1.765-30.82), or those who did not know (OR=11.448, 95% CI=1.996-65.655 ) had a low willingness to vaccinate against rabies. The willingness to recommend rabies vaccination for rabies prevention (OR=2.936, 95% CI=1.218-7.076) was lower among those who believed that rabies vaccination for rabies prevention (OR=2.936, 95% CI=1.218-7.076) was not allowed before injury (OR=2.198, 95% CI=1.044-4.628) except for other positions of veterinarians, and were aged 25-30 years (OR=2.779, 95% CI=1.237-6.224).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion\u003c/strong\u003e: Targeted interventions should address economic barriers and knowledge gaps, particularly the prevalent \"no exposure, no vaccination\" misconception.\u003c/p\u003e","manuscriptTitle":"Determinants of rabies pre-exposure prophylaxis vaccination willingness among pet hospital staff in Guiyang, China: a cross-sectional study","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-09-22 06:45:09","doi":"10.21203/rs.3.rs-6625650/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"e9ea42a5-9c56-48f7-8e81-c16473bab7d7","owner":[],"postedDate":"September 22nd, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2026-01-07T08:56:01+00:00","versionOfRecord":[],"versionCreatedAt":"2025-09-22 06:45:09","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-6625650","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6625650","identity":"rs-6625650","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}