Addressing the increasing incidence of allergic diseases in young working individuals and their effective management with sublingual immunotherapy in Mumbai

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Background: Allergic disease are on an increase in office workers and students, due to increasing climate change and environmental exposure Objective: To define the role of the skin prick test in identifying common inhalant allergens in allergic rhinitis patients and selecting the allergens for optimum sublingual immunotherapy Methods: : 773 patients were tested in Mumbai from November 2018 to December 2023 by skin prick test. Sublingual Immunotherapy was initiated in 301 patients. Pre and post-therapy SNOT22 symptom score was noted for 3-6 months in a subset of 50 patients. Results: : It was found that 52% were in the age group 20-40 with almost equal male /female ratio, 95% had primarily allergic rhinitis, house dust mites 84%, with pollen to be second, 63% each being Prosopis and A maranthus. 40% opted for sublingual immunotherapy, out of which results of a subset of 35 %( 50) in the first 6 months, showed significant improvement verified by statistical analysis Conclusion: Allergic rhinitis is fairly prevalent in both office workers and students due to dust exposure, and poor environmental hygiene. Important allergens are House dust mites and pollen are the major allergens. Skin prick test is the method of choice for diagnosis and selection of allergens. Sublingual immunotherapy is the safest and most effective way of symptom control.
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Addressing the increasing incidence of allergic diseases in young working individuals and their effective management with sublingual immunotherapy in Mumbai | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 23 July 2025 V1 Latest version Share on Addressing the increasing incidence of allergic diseases in young working individuals and their effective management with sublingual immunotherapy in Mumbai Author : Anita Babtiwale 0000-0003-4445-7072 [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.175327226.68654169/v1 Published International Journal Of Community Medicine And Public Health Version of record Peer review timeline 146 views 102 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Background: Allergic disease are on an increase in office workers and students, due to increasing climate change and environmental exposure Objective: To define the role of the skin prick test in identifying common inhalant allergens in allergic rhinitis patients and selecting the allergens for optimum sublingual immunotherapy Methods: 773 patients were tested in Mumbai from November 2018 to December 2023 by skin prick test. Sublingual Immunotherapy was initiated in 301 patients. Pre and post-therapy SNOT22 symptom score was noted for 3-6 months in a subset of 50 patients. Results: It was found that 52% were in the age group 20-40 with almost equal male /female ratio, 95% had primarily allergic rhinitis, house dust mites 84%, with pollen to be second, 63% each being Prosopis and A maranthus. 40% opted for sublingual immunotherapy, out of which results of a subset of 35 %( 50) in the first 6 months, showed significant improvement verified by statistical analysis Conclusion: Allergic rhinitis is fairly prevalent in both office workers and students due to dust exposure, and poor environmental hygiene. Important allergens are House dust mites and pollen are the major allergens. Skin prick test is the method of choice for diagnosis and selection of allergens. Sublingual immunotherapy is the safest and most effective way of symptom control. Supplementary Material File (dr anita babtiwale allergic rhinitis and slit study.docx) Download 78.38 KB Information & Authors Information Version history V1 Version 1 23 July 2025 Peer review timeline Published International Journal Of Community Medicine And Public Health Version of Record 30 Apr 2026 Published Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords allergy diagnosis allergy treament environment and hygiene hypothesis immunotherapy and tolerance induction immunotherapy vaccines and mechanisms Authors Affiliations Anita Babtiwale 0000-0003-4445-7072 [email protected] Apollo Specialty Hospitals Pvt Ltd View all articles by this author Metrics & Citations Metrics Article Usage 146 views 102 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Anita Babtiwale. Addressing the increasing incidence of allergic diseases in young working individuals and their effective management with sublingual immunotherapy in Mumbai. 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