Hierarchical composition of reliable recombinase logic devices
preprint
OA: closed
CC-BY-NC-ND-4.0
Abstract
We provide a systematic framework for engineering reliable recombinase logic devices by hierarchical composition of well-characterized, optimized recombinase switches. We apply this framework to build a recombinase logic device family supporting up to 4-input Boolean logic. This work will support the predictable engineering of several classes of recombinase devices to reliably control cellular behavior.
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Source provenance
- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00
- unpaywall
- last seen: 2026-05-30T02:00:01.510937+00:00
License: CC-BY-NC-ND-4.0