IVF Stimulation Protocols and Outcomes in Women with Endometriosis

Jwal Banker, Henrique D’Allagnol, Juan A. García-Velasco
In: Endometriosis-related Infertility · 2024 · pp. 199–207 · doi:10.1007/978-3-031-50662-8_15 · W4392309798
book-chapter OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

Endometriosis presents challenges for fertility, and while various IVF stimulation protocols like long, antagonist, and PPOS exist, none are definitively superior, though early intervention is beneficial.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This 2024 chapter reviews how different ovarian stimulation approaches for IVF in women with endometriosis compare in outcomes, focusing on long (GnRH agonist) versus antagonist protocols and newer progesterone-primed only (PPOS) strategies, alongside the impact of advances like embryo vitrification. It synthesizes evidence suggesting that no single protocol has been proven superior, while noting that antagonist regimens are shorter and described as safer, and PPOS may offer safety and cost/compliance advantages. A key caveat stated is that the evidence base remains unsettled—ongoing debate persists—and protocol comparisons may not yield a clear winner across studies. This paper is centrally about endometriosis — it reviews IVF stimulation protocol choices (long vs antagonist vs PPOS) and their reported outcomes in women with endometriosis.

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endometriosis

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License: CC0 · commercial use OK