Ectopic decidua and metastatic squamous carcinoma: Presentation in a single pelvic lymph node

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AI-generated summary by claude@2026-06, 2026-06-07

This case report describes a single pelvic lymph node containing both ectopic decidua and metastatic squamous carcinoma, highlighting key morphologic features to distinguish these two entities.

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Abstract

The presence of ectopic decidua in pelvic lymph nodes from patients with squamous carcinoma of the cervix makes evaluation for metastatic disease difficult due to the light microscopic similarity between decidua and sheets of squamous epithelial cells. A patient is present in whom decidualized endometriosis was intimately associated with metastatic moderately differentiate squamous carcinoma in a single pelvic lymph node. This phenomenon afforded an excellent opportunity to study the unique morphologic features that distinguish these two entities. A prior report of this kind was not found. In the absence of obvious squamous differentiation (i.e., intercellular bridges, dyskeratosis, and keratin "pearl" formation), as is frequently the case with squamous carcinoma of the cervix, the light microscopic features that are most useful in distinguishing squamous carcinoma from decidua include the presence of well-defined nests of cohesive cells, nuclear hyperchromasia, and cellular pleomorphism.

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Condition tags

endometriosis

MeSH descriptors

Carcinoma, Squamous Cell Choristoma Decidua Lymph Nodes Uterine Cervical Neoplasms Adult Carcinoma, Squamous Cell Carcinoma, Squamous Cell Choristoma Choristoma Female Humans Lymphatic Metastasis Lymph Node Excision Lymph Nodes Neoplasm Invasiveness Pregnancy Uterine Cervical Neoplasms Uterine Cervical Neoplasms

Citation neighborhood

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References (5)

Cited by (5)

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