Metabolic engineering for provitamin D3 biosynthesis in tomato

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Abstract

Abstract Providing adequate vitamin D3 for the human diet is a long-standing goal of crop breeding because most plants have relatively low levels of this nutrient naturally. Using CRISPR-Cas9 editing of the tomato genome, we increased provitamin D3 levels in tomato fruits to up to 1 mg per 100 grams dry weight. Use of this provitamin D3 tomato could ameliorate widespread vitamin D deficiencies around the world.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00
unpaywall
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License: CC-BY-4.0