The Clinical Study on Endometriosis combined with infertile women endocrine
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Abstract
objective to explore endometriosis merger infertility women autoantibodies immune and endocrine hormone levels.Methods selected our hospital from January 2012 to December 2014 120 examples of intrauterine membrane endometriosis(EMS) and infertility patients,and depending on the type of disease in patients,divided into pure with infertility group(group A),38 cases,pure endometriosis group(group B) merger of 42 cases of endometriosis and infertility group 40 cases(AB),and 40 cases of healthy checkup,as control group,took chemical immunofluorescence method for determination of T(testosterone) in groups of patients serum,INS(insulin) and E2(estradiol),PRL(prolactin),FSH(follicle-stimulating hormone) and LH(luteinizing hormone) level,and took with ELISA enzyme immune method for determination of each group were AOAb(ovarian) antibodies,ACAb(anti cardiolipin antibody),ASAb(antisperm antibody),HCGAb(resistance to fluff gonadotropin) antibodies and EMAb(resistance to endometrial antibody)positive.Results patients of group AB with PRL,INS,T,E2 levels were significandy higher than that of group A and group B,the difference was statistically significant(P 0.05),FSH and LH level difference three groups was not significant(P0.05),the difference was not statistically significance,group A and the control group in patients with serum PRL level was significantly lower than that of group B(P 0.05),other indicators has no marked difference(P 0.05);Antibody total positive rate of group AB was obviously higher than that of the other three groups(P 0.05),the rate of positive of antibody of differences between group A and group B was not statistically significant(P 0.05).Conclusion the main factors that cause endometriosis patients with infertility may be due to a endometriosis immune imbalance of T,E2,PRL and endocrine abnormalities,through the analysis of the level of endocrine research,which aims to provide a reliable basis for clinical.
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- last seen: 2026-06-10T17:14:06.276822+00:00
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