Experience of Serious Intestinal Hemorrhage and Perforation in Small Bowel Lymphoma: A Case Report

Abstract Background: There have been several reports of complications of small bowel lymphoma, such as bleeding, obstruction, and perforation, which require emergency surgery. It is hardly showed complication of bleeding and wound dehiscence for diffuse large B cell lymphoma with distal ileum involvement, which needed urgent surgery and medical management. Chemotherapy is also important when treating small bowel lymphoma, but complications such as bleeding and perforation should always be kept in mind.Case presentation: A 65 year-old man with stage III diffuse large B-cell lymphoma of the activated-B cell (ABC) type with distal ileum involvement experienced both intestinal bleeding and perforation during the course of treatment. As the patient was diagnosed with stage III disease, resection before chemotherapy was not considered due to the resulting delay in chemotherapy, which necessitated sufficient tissue healing. Conclusion: As shown in this case, complications such as bleeding and perforation should always be considered for the treatment of small bowel lymphoma, and surgery is necessary in this situation. After surgery of the small bowel, subsequent chemotherapy could cause the wound dehiscence and perforation; therefore, adequate recovery time should be given before chemotherapy.