Endometriose mit Ureterbeteiligung

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This report details two cases of histologically confirmed endometriosis affecting the ureter and causing uronephrosis, highlighting the rarity and delayed diagnosis of this condition.

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This paper presents two case reports of women with histologically confirmed endometriosis involving the ureter, which resulted in significant hydronephrosis. The first patient underwent laparoscopic diagnosis followed by percutaneous nephrostomy and ureteral reimplantation via a psoas-hitch technique after resection of the affected segment. The second patient required an open laparotomy for adhesion lysis and salpingectomy, alongside urological intervention including partial ureteral resection and reconstruction using the same psoas-hitch method. The authors conclude that ureteral involvement is a rare manifestation occurring in one to two percent of patients, often leading to delayed diagnosis due to its asymptomatic nature or rarity, necessitating individualized treatment plans based on age and fertility desires. This paper is centrally about endometriosis — specifically deep infiltrating endometriosis affecting the urinary tract and requiring multidisciplinary surgical management.

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Abstract

INTRODUCTION: Endometriosis is a benign proliferation of discarded or ectopic endometrial mucus membranes which retain the histological features and biological reactions of uterine mucus membranes. This tissue is not capable of independent proliferation but is subject to the influence of estrogen progesterone. In this report we describe the clinical course of two patients with histologically proven endometriosis with participation of the uteral region and uronephrosis. CASE REPORT 1: Left-sided uronephrosis was diagnosed in a 36-year-old female during a sonographic examination for hypertension. Our gynaecologists obtained histological proof of endometriosis by laparoscopy. Two days after the laparoscopic detection of foci of endometriosis in the intestine, Douglas' pouch, ovaries as well as in the region of the left terminal ureter, a left percutaneous renal fistula was created under sonographic and radiological control. After resection of the afflicted section of the ureter, implantation of a new left ureter was performed by means of a psoas-hitch plasty. CASE REPORT 2: A 30-year-old female presented with a months-long history of dyspareunia, pain on palpation of the Douglas' pouch, occasional pain on bowel movements and back pain. In addition she had been trying for years to become pregnant. On sonography renal congestion grade III was detected. After admission and appropriate preparation, one week later an open laparotomy with lysis of intestinal as well as uterine adhesions, salpingectomy and, by the urologist, partial left uteral resection with new implantation by the psoas-hitch technique. CONCLUSIONS: Endometriosis of the urinary tract is a rare occurrence affecting 1 - 2 % of all endometriosis patients with the urinary bladder being the most commonly affected site. Endometriosis with involvement of the ureter is often diagnosed very late because of the rareness of this situation and its asymptomatic course. An individual therapy plan depending first of all on the patient's age, desire for children, and the extent of the endometriosis foci should always be attempted.
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Subscribe to RSS DOI: 10.1055/s-2006-932161 Endometriose mit Ureterbeteiligung Erlanger Erfahrungen am Beispiel zweier KasuistikenEndometriosis Involving the UreterThe Erlangen Experience Exemplified by Two Case ReportsPublication History Publication Date: 09 February 2007 (online) Zusammenfassung Einleitung: Die Endometriose ist eine gutartige Wucherung versprengter bzw. ektoper Endometriumschleimhaut, die die histologischen Merkmale und biologischen Reaktionen der Uterusschleimhaut beibehalten hat. Es handelt sich dabei um Gewebe, das nicht zu selbständiger Proliferation befähigt ist, sondern dem Einfluss von Östrogen und Progesteron unterliegt. In dieser Arbeit werden die Krankheitsverläufe von zwei unserer Patientinnen mit histologisch nachgewiesener Endometriose mit Beteiligung im Harnleiterbereich mit Harnstauungsnieren dargestellt. Fallbericht 1: Bei einer 36-jährigen Patientin wurde im Rahmen einer Hypertonieabklärung sonographisch eine Harnstauungsniere links diagnostiziert. Durch unsere Gynäkologen konnte durch eine Laparoskopie histologisch eine Endometriose festgestellt werden. Zwei Tage nach dem laparoskopischen Nachweis von Endometrioseherden im Darm, Douglasraum, an den Ovarien, sowie im Bereich des terminalen Harnleiters links erfolgte die perkutane Nierenfistelanlage links, ultraschall- und radiologisch kontrolliert. Urologisch wurde nach Resektion des befallenen Ureterabschnittes eine Harnleiterneueinpflanzung links mit Psoas-Hitch-Plastik durchgeführt. Fallbericht 2: Eine 30-jährige Patientin klagte seit Monaten über Dyspareunie, Druckschmerzen im Douglasraum, gelegentliche Defäkationsschmerzen und Kreuzschmerzen. Außerdem bestand seit Jahren ein unerfüllter Kinderwunsch. Ein Nierenaufstau III. Grades wurde sonographisch nachgewiesen. Nach stationärer Aufnahme und entsprechender Vorbereitung erfolgte eine Woche später eine offene Laparotomie mit Adhäsiolyse des Darmes, sowie des Ovars, Salpingektomie und urologischerseits nach partieller Ureterresektion eine Harnleiterneueinpflanzung in Psoas-Hitch-Technik links. Schlussfolgerung: Die Endometriose des Harntraktes ist mit 1 - 2 % der von der Endometriose betroffenen Patientinnen eine seltene Erkrankung, wobei die Harnblase der häufigste Lokalisationsort ist. Eine Endometriose mit Harnleiterbeteiligung wird oft sehr spät diagnostiziert, da asymptomatische Verläufe und die Seltenheit dieses Krankheitsbildes häufig zu einer verspäteten Diagnoseerhebung führen. Es sollte stets ein individuelles Therapiemanagement angestrebt werden, das in erster Linie vom Alter der Patientin, bestehendem Kinderwunsch und von der Ausdehnung des Endometrioseherdes abhängig ist. Abstract Introduction: Endometriosis is a benign proliferation of discarded or ectopic endometrial mucus membranes which retain the histological features and biological reactions of uterine mucus membranes. This tissue is not capable of independent proliferation but is subject to the influence of estrogen progesterone. In this report we describe the clinical course of two patients with histologically proven endometriosis with participation of the uteral region and uronephrosis. Case Report 1: Left-sided uronephrosis was diagnosed in a 36-year-old female during a sonographic examination for hypertension. Our gynaecologists obtained histological proof of endometriosis by laparoscopy. Two days after the laparoscopic detection of foci of endometriosis in the intestine, Douglas' pouch, ovaries as well as in the region of the left terminal ureter, a left percutaneous renal fistula was created under sonographic and radiological control. After resection of the afflicted section of the ureter, implantation of a new left ureter was performed by means of a psoas-hitch plasty. Case Report 2: A 30-year-old female presented with a months-long history of dyspareunia, pain on palpation of the Douglas' pouch, occasional pain on bowel movements and back pain. In addition she had been trying for years to become pregnant. On sonography renal congestion grade III was detected. After admission and appropriate preparation, one week later an open laparotomy with lysis of intestinal as well as uterine adhesions, salpingectomy and, by the urologist, partial left uteral resection with new implantation by the psoas-hitch technique. Conclusions: Endometriosis of the urinary tract is a rare occurrence affecting 1 - 2 % of all endometriosis patients with the urinary bladder being the most commonly affected site. Endometriosis with involvement of the ureter is often diagnosed very late because of the rareness of this situation and its asymptomatic course. An individual therapy plan depending first of all on the patient's age, desire for children, and the extent of the endometriosis foci should always be attempted. Schlüsselwörter Endometriose - Ureterbeteiligung - Ureterneueinpflanzung - Psoas-Hitch Key words endometriosis - uretal involvement - uretal reimplantation - psoas hitch Literatur - 1 El Kahder K, Guille F, Patard J J, Mhidia A, Ziade J, Manunta A, Lobel B. Ureteral reimplantation on psoas bladder:long term results. Acta Urol Belg. 1998; 66 (4) 15-20 - 2 Haag P, Hahnart N, Müller M. Gynäkologie und Urologie für Studium und Praxis. 1. Auflage. 2003/2004: 50-52 - 3 Horn L C, Do Minh M, Stolzenburg J U. Intrinsic form of ureteral endometriosis causing ureteral obstruction and partial loss of kidney function. Urologia internationalis. 2004; 73 (2) 181-184 - 4 Jubanyik K J, Comite F. Extrapelvic endometriosis. Obstet Gynecol Clin North Am. 1997; 24 411-440 Dr. med. Vahudin Zugor Friedrich-Alexander-Universität Erlangen-Nürnberg Urologische Klinik mit Poliklinik Krankenhausstr. 12 D-91054 Erlangen Phone: 0049-9131-853 36 83 Fax: 0049-9131-853 48 51 Email: [email protected]

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Condition tags

dyspareuniaendometriosis

MeSH descriptors

Endometriosis Ureteral Diseases Adult Dyspareunia Dyspareunia Dyspareunia Endometriosis Endometriosis Female Humans Hydronephrosis Hydronephrosis Hydronephrosis Postoperative Complications Postoperative Complications Ureter Ureter Ureteral Diseases Ureteral Diseases Ureteral Obstruction

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