Design and Validation of an IoT-Based Blood Pressure Monitoring System for Rabbits

Telemedicine, driven by the Internet of Things (IoT) and next-generation mobile networks, is essential for managing cardiovascular diseases, where hypertension remains the primary risk factor. In preclinical research, rabbits are superior biological models compared to rodents due to their human-like lipid metabolism. However, conventional blood pressure monitoring in this species is hindered by significant limitations: existing systems are non-portable, lack real-time capabilities, and often necessitate terminal procedures (euthanasia). To address these challenges, this study presents a portable, minimally invasive monitoring system utilizing a pressure transducer in the central auricular artery. The device integrates IoT technology for digital signal processing and seamless wireless data transmission to cloud platforms. This development enables continuous, real-time hemodynamic tracking throughout the experimental period without requiring permanent tethering to desktop hardware. By reducing invasiveness and enhancing data mobility, this system provides a robust framework for the preclinical evaluation of antihypertensive agents and cardiovascular mechanisms, bridging the gap between edge computing and remote clinical diagnostics.