Ovarian stripping versus cystectomy: recurrence of endometriosis and pregnancy rate

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Cystectomy for ovarian endometrioma showed significantly lower recurrence of the condition and pain, and a higher pregnancy rate compared to stripping, with fewer specimens showing adjacent healthy ovarian tissue.

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This study compared ovarian stripping versus cystectomy for women with unilateral ovarian endometrioma >3 cm, all of whom received the same postoperative GnRH analog therapy; participants were 25–40 years old with regular menses, normal semen, and confirmed tubal patency, with exclusions including adenomyosis and deep endometriosis. Over 2 years, ultrasonographic endometrioma recurrence was 55.6% after stripping versus 15.4% after cystectomy, and symptomatic recurrence was 53.3% versus 21.8%, respectively, with both differences statistically significant. Spontaneous pregnancy rates were lower after stripping (4.4%) than after cystectomy (22.3%), while stripping was associated with a smaller proportion of specimens showing adjacent healthy ovarian tissue (26.6% vs 50%), though the paper’s conclusion favors cystectomy. This paper is centrally about endometriosis—specifically surgical technique (stripping vs cystectomy) for ovarian endometrioma with measured recurrence and pregnancy outcomes.

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Abstract

PURPOSE: To compare two different surgical techniques, stripping or cystectomy, in patients treated with the same post-operative medical therapy in terms of recurrence of endometrioma, recurrence of pain and spontaneous pregnancy rate within 2 years from surgery. METHODS: The inclusion criteria of this study were: (1) 25-40 years old; (2) ovarian endometrioma more than 3 cm of diameter detected by transvaginal ultrasonography (3) regular menstrual cycle (4) post-operative treatment with GnRH analogs, (5) tubal patency assessed by laparoscopic chromopertubation (6) normal human semen characteristics. Exclusion criteria were uterine myoma, previous medical treatment for endometriosis, presence of adenomyosis, previous surgery of ovarian endometrioma, multiple cysts, bilateral involvement, co-existence of deep endometriosis. Patients were assigned to two study groups: group A (N = 45) patients undergoing stripping technique and group B (N = 64) patients undergoing cystectomy technique for ovarian endometrioma. RESULTS: In group B the percentage of ultrasonographic recurrence (15.4 %, N = 15) is much lower than in group A (55.6 %, N = 25). (p value 0.001). In group B the percentage of symptomatic recurrence (21.8 %, N = 14) is much lower than in group A (53.3 %, N = 24) (p value 0.001). Spontaneous pregnancy rate in group A patients was of 4.4 % (N = 2) and in group B 22.3 % (N = 21), (p value 0.0072). However, the percentage of specimen with adjacent healthy ovarian tissue was lower in group A (26.6 %) than in group B (50 %) (p value 0.01). CONCLUSIONS: Among the different treatment options for surgical treatment of ovarian endometrioma, in our experience cystectomy appears to be the most appropriate treatment, both in terms of recurrence and pregnancy rate.
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Abstract

Purpose To compare two different surgical techniques, stripping or cystectomy, in patients treated with the same post-operative medical therapy in terms of recurrence of endometrioma, recurrence of pain and spontaneous pregnancy rate within 2 years from surgery.

Methods

The inclusion criteria of this study were: (1) 25–40 years old; (2) ovarian endometrioma more than 3 cm of diameter detected by transvaginal ultrasonography (3) regular menstrual cycle (4) post-operative treatment with GnRH analogs, (5) tubal patency assessed by laparoscopic chromopertubation (6) normal human semen characteristics. Exclusion criteria were uterine myoma, previous medical treatment for endometriosis, presence of adenomyosis, previous surgery of ovarian endometrioma, multiple cysts, bilateral involvement, co-existence of deep endometriosis. Patients were assigned to two study groups: group A (N = 45) patients undergoing stripping technique and group B (N = 64) patients undergoing cystectomy technique for ovarian endometrioma.

Results

In group B the percentage of ultrasonographic recurrence (15.4 %, N = 15) is much lower than in group A (55.6 %, N = 25). (p value 0.001). In group B the percentage of symptomatic recurrence (21.8 %, N = 14) is much lower than in group A (53.3 %, N = 24) (p value 0.001). Spontaneous pregnancy rate in group A patients was of 4.4 % (N = 2) and in group B 22.3 % (N = 21), (p value 0.0072). However, the percentage of specimen with adjacent healthy ovarian tissue was lower in group A (26.6 %) than in group B (50 %) (p value 0.01).

Conclusions

Among the different treatment options for surgical treatment of ovarian endometrioma, in our experience cystectomy appears to be the most appropriate treatment, both in terms of recurrence and pregnancy rate. Similar content being viewed by others

References

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Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Moscarini, M., Milazzo, G.N., Assorgi, C. et al. Ovarian stripping versus cystectomy: recurrence of endometriosis and pregnancy rate. Arch Gynecol Obstet 290, 163–167 (2014). https://doi.org/10.1007/s00404-014-3158-z Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-014-3158-z

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Condition tags

endometriosischronic_pelvic_painadenomyosisendometrioma

MeSH descriptors

Cystectomy Endometriosis Gynecologic Surgical Procedures Ovarian Diseases Pregnancy Rate Adult Endometriosis Endometriosis Female Gonadotropin-Releasing Hormone Humans Laparoscopy Ovarian Diseases Pelvic Pain Pelvic Pain Pregnancy Recurrence Treatment Outcome Ultrasonography

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