Effects of PKF 115–584 on total and active forms of MMP-2 and MMP-9.

A, B: Total and active forms of MMP-2 in non-treated and PKF 115–584–treated epithelial (A) and stromal (B) cells of endometriotic tissue and matched eutopic endometrium of patients with endometriosis. C, D: Total and active forms of MMP-9 in non-treated and PKF 115–584–treated epithelial (C) and stromal (D) cells of endometriosis and matched eutopic endometrium of patients with endometriosis. Values are normalized to the total protein content of the culture supernatants. Results are presented as the mean +SEM. Endo: endometriosis, EE: matched eutopic endometrium. Endo: (epithelial cells: n = 6, stromal cells: n = 6). EE: (epithelial cells: n = 6, stromal cells: n = 6). a: p<.05 versus PKF 115–584–treated endometrial epithelial or stromal cells.