IRREVERSIBLE BICYCLIC INHIBITORS OF TYROSINE KINASES

1999
OA: closed

Abstract

The present invention provides compounds that are irreversible inhibitors of tyrosine kinases of formula (I) or (II). Also provided is a method of treating cancer, restenosis, atherosclerosis, endometriosis, and psoriasis and a pharmaceutical composition that comprises a compound that is an irreversible inhibitor of tyrosine kinases. In formulas (I) and (II), Z, X, Y or R are as defined in the description.

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europepmc
last seen: 2026-07-08T06:14:57.058073+00:00