Clear Cell Ovarian Carcinoma Following Long‐Term Tamoxifen Use

T. Scott Jennings, Mary E. Haddad, Mary Haddad, Timothy M. Smith
The breast journal · 1999 · vol. 5(2) , pp. 132–135 · doi:10.1046/j.1524-4741.1999.00137.x · PMID:11348273 · W1991695890
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Abstract

A case of clear cell ovarian cancer and endometriosis in a postmenopausal patient following adjuvant tamoxifen for breast cancer is presented. Immunohistochemistry demonstrated the tumor to be positive for progesterone receptor protein but not estrogen receptor protein; the endometriosis was positive for both proteins. Literature review reveals this to be the first report of both clear cell ovarian cancer and endometriosis following tamoxifen use, and the third report of epithelial ovarian cancer associated with tamoxifen.

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endometriosis

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