Anics full organ simulations with a sex-specific dimension
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This paper presents cardiac and uterine simulations using the Alya code, incorporating hormonal influences for sex-specific behavior and demonstrating virtual clinical trials for drug safety and patient-specific reproductive health studies.
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Abstract
The current state of the art simulations on cardiac and uterine simulations will be presented employing the BSC’s finite elements code: Alya. An overview of the different scales at which we are solving the sub-cellular to full organ physics will be explained, including the aspects of hormonal influence on sex-specific functional behaviour. The creation of an in-silico human clinical trial will be employed to demonstrate the use of virtual human populations to assess drug cardiac safety. Furthermore, some of the simulations created to study female reproductive health will be shown, towards the use of patientspecific simulations to study endometriosis and infertility.
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- openalex
- last seen: 2026-05-11T08:17:14.631231+00:00
License: CC0
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