Antiviral activity of pacific oyster (Crassostrea gigas) hemolymph against a human coronavirus
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Abstract
ABSTRACT Coronaviruses can cause severe respiratory infections in humans. In this study we assessed the antiviral activity of Pacific oyster ( Crassostrea gigas ) hemolymph against a human coronavirus, HCoV-229E. An eight-fold reduction in infectivity of HCoV-229E on Huh-7 cells was observed in the presence of 10% C. gigas hemolymph. Antiviral activity of C. gigas hemolymph positively correlated with its concentration and appears to be active during an intracellular stage of HCoV-229E infection.
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- europepmc
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