Analysis of the relationship between endometriosis and ovarian cancer

Objective To explore the relationship between ovarian cancer and endometriosis by analyzing the cases of ovary cancer with endometriosis.Methods 362 patients with primary ovarian cancer between January 2003 and December 2010 were analyzed retrospectively.Among the 362 cases,17 originated from endometriosis(group A),16 were found to have CO-existing ovarian endometriosis(group B),and the remaining 329 had no ovarian endometriosis at all(group C).Results The incidence of stage Ⅱ in group A and group B was 70.6% and 56.2%,and incidence of stage Ⅲ in group C was 47.7%.All three groups had a subtype of serious carcinoma.ConclusionsThe diagnosis of malignant change of endometriosis may be associated with the degree and classification of ovary cancer.Patients of endometriosis-associated epithelial ovarian carcinoma,especially patients with tumors arising from endometriosis,were found to be younger,having a better survival and were mostly diagnosed with the subtype of clear-cell and endometrio-carcinoma.There is a compact relationship between endometriosis and ovarian cancer,especially clear cell carcinoma and endometrio-carcinoma.Endometriosis causes a high risk for ovarian cancer.