IMPROVING THE QUALITY OF DIAGNOSIS OF THE SPREAD OF OVARIAN ENDOMETRIOSIS

The article examines the diagnosis of ovarian endometriosis, which is a chronic, estrogen-dependent, progressive disease. The article deeply discloses the history of the discovery and study of endometriosis; the works of such scientists as Russel W.W., Sampson J.A., Scott R.B., Ranney B., Noble A.D., DmowskiW.P., Gebel H.M., Braun D.P. and others are discussed in the article. It was found that endometriosis is defined as the presence of endometrial glands and stroma-like lesions outside the uterus. The authors noted that endometriosis can undergo malignant transformation; however, it is still not possible to identify intermediate precursors. The authors concluded that the development of reliable biomarkers can provide a positive result in the early detection of endometriosis-associated ovarian cancer. To date, the most promising specific potential biomarker of endometriosis is miRNAs, discovered relatively recently. The search for a biomarker or a set of biomarkers is still open.